Nucleic Acids Dr. Shivani Gupta, PGGCG-11, Chandigarh.

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Presentation transcript:

Nucleic Acids Dr. Shivani Gupta, PGGCG-11, Chandigarh

DNA RNA

DNA Backbone Structure Alternate phosphate and sugar (deoxyribose), phosphate ester bonds Alternate phosphate and sugar (deoxyribose), phosphate ester bonds

DNA Backbone Structure Alternate phosphate and sugar (deoxyribose), phosphate ester bonds Alternate phosphate and sugar (deoxyribose), phosphate ester bonds

DNA RNA

DNA Primary Structure Summary Backbone (sugar+phophate with phosphate ester bonds and base or heterocyclicamine side chains Backbone (sugar+phophate with phosphate ester bonds and base or heterocyclicamine side chains

DNA RNA

DNA Double Helix Base pairing by unique hydrogen bonds Base pairing by unique hydrogen bonds C - G and A - T pairs C - G and A - T pairs

DNA Double Helix Base pairing by unique hydrogen bonds Base pairing by unique hydrogen bonds C - G and A - T pairs C - G and A - T pairs

DNA

DNA Replication Polymerase enzymes which guide replication Polymerase enzymes which guide replication

DNA Replication Polymerase enzymes which guide replication Polymerase enzymes which guide replication

DNA Replication Complementary base pairs form new strands. Complementary base pairs form new strands.

DNA

DNA

RNA Transcription In nucleus, DNA guides the synthesis of mRNA In nucleus, DNA guides the synthesis of mRNA

RNA Transcription RNA polymerase and elongation reaction RNA polymerase and elongation reaction

RNA Transcription RNA polymerase and elongation reaction RNA polymerase and elongation reaction

Types of RNA mRNA contains codons which code for amino acids. mRNA contains codons which code for amino acids.

DNA

Types of RNA rRNA - Ribosome - contains enzymes and keeps everything together rRNA - Ribosome - contains enzymes and keeps everything together

Types of RNA tRNA - Transfer RNA carries amino acid and read codons on m-RNA through its own anticodons. tRNA - Transfer RNA carries amino acid and read codons on m-RNA through its own anticodons.

Types of RNA tRNA - Transfer RNA carries amino acid and read codons on m-RNA through its own anticodons. tRNA - Transfer RNA carries amino acid and read codons on m-RNA through its own anticodons.

Protein Synthesis