Nutrient deficiencies of the obese child and adolescent ML FRELUT, MD Service d'Endocrinologie et Diabétologie Pédiatriques Centre hospitalier universitaire.

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Nutrient deficiencies of the obese child and adolescent ML FRELUT, MD Service d'Endocrinologie et Diabétologie Pédiatriques Centre hospitalier universitaire de Bicêtre Hôpitaux Universitaires Paris Sud (AP-HP) France ECOG eBOOK ML Frelut

Excess fat mass + Association to several nutrients deficiencies = Double burden ECOG eBOOK ML Frelut Obesity

The keys of the diagnosis Good knowledge of the local nutritional situation Clinics Dietary recall Biological assesment ECOG eBOOK ML Frelut

Top 6 deficiencies Vitamin A Vitamin D Vitamin E Folate 3 Minerals /trace elements Iron Zinc Selenium ECOG eBOOK ML Frelut 4 vitamins

The pitfalls of the biological diagnosis Obesity is a mild inflammatory disease: impact on proteins  overestimation of ferritine  Underestimation of retinol binding protein Increased fat mass  Unknown stores of fat soluble vitamins: A, D,E ECOG eBOOK ML Frelut

Consequences of nutritional deficiencies Addition of classical consequences and Increase of complications of obesity – Cardiovascular risk – Insulin resistance – Liver damage – …. ECOG eBOOK ML Frelut