Fluid and Electrolyte Balance
Electrolytes Electrolytes (sodium, potassium, chloride) help keep fluids in the proper compartments –Intracellular water –Extracellular water
Electrolytes Enable nerves to respond Signal muscles to contract
Primary electrolytes-major minerals More than 0.1 grams (or 100 mg) required per day in the diet These include: –Sodium –Potassium –Chloride –Phosphorus
Sodium: + ion of table salt (NaCl) No known human diet lacks sodium Minimum requirement about 500 mg/day –estimated safe and adequate Daily intake Average intake in US for men = 3300 mg/day(equal to 8 grams of salt/day) AI = 1500 mg/day <2400 mg/day most common rec.
Sodium Functions Scientific Method Google Image Result for Fluid balance Blood pressure Acid-base balance Nerve transmission Active transport mechanism
Hypertension Definition Diastolic Blood Pressure – > 90 mm Hg Systolic Blood Pressure – >140 mm Hg Desirable < 120/80
Hypertension and Disease Stroke –2/3rds with first stroke have HTN –7 times more likely than normal Coronary heart disease –1/2 with first MI have HTN –3 times more likely than normal End-stage Renal Failure Blindness
Blood Pressure
Risk Factors Age Ethnicity Family History Obesity
Diet and Hypertension Weight Loss Moderate weight loss Regular exercise
Diet and Hypertension Alcohol – < 1-2 servings per day –>2 servings increases risk of HTN Potassium – fruits and vegetables Fish Oils Calcium Calcium, Linus Pauling Institute's Micronutrient Information Center Calcium, Linus Pauling Institute's Micronutrient Information Center
The DASH Diet D ietary A pproaches to S top H ypertension Diet rich in –fruit –vegetable –grain products Low/non fat dairy, fish and meats
DASH-Na Conclusions DASH diet lowers BP Sodium reduction lowers BP Combination of DASH and Na reduction effects greater than separately –DASH+low-Na reduced Systolic BP by: 11.5mm Hg in HTN subjects 7.1 mm Hg in borderline HTN subjects