1. Cognitive Decline: A Natural Approach
Dr. Jonathan Mendoza, DC RN

2. What is Cognitive Decline?
Can be age-related deterioration in:
Ability to learn new concepts
Comprehend and interpret language
Inability to solve problems
Memory Loss
Lose train of thought
Confusion
Difficulty with communication

3. Causes of Cognitive Decline
Congenital
Infection at birth
Malnutrition
Head injury
Stroke
Lead poisoning
High Blood Pressure
Alcohol
Vitamin Deficiencies
Dementia
Alzheimer's
Parkinson's

4. Vitamin/Nutritional Deficiencies
Studies have shown a link to a deficiency in the following vitamins/nutrients:
Vitamin D
Vitamin B12
Vitamin B6
Vitamin B9
Vitamin E
Omega 3 DHA
CoQ10

5. Being Overweight
Research presented at the Annual American Academy of Neurology suggests that overeating can double the risk of cognitive decline in persons over 70
Increased caloric intake (+2,000 calories/daily) can lead to oxidative damage leading to structural changes in the brain
Restriction of caloric intake throughout life can reduce risk

6. Oxidative Stress
Body’s response to physical, mental, and emotional stress that releases free radicals
Free radicals cause damage to all components of cells such as proteins, lipids, and DNA
Causes neurological damage and has been linked to such conditions as:
Parkinson's
Alzheimer's
ALS (Lou Gehrig’s Disease)
Also linked to cardiovascular disease that causes plaque formation

7. Oxidative Stress=Inflammation
Parkinson's:
Increased methionine sulfoxide reductase; MSR will cause a decline locomotor and circadian rhythm
Alzheimer's:
shows 70% loss of locus coeruleus cells that provide norepinephrine
Decreased production of acetylcholine, important neurotransmitter that affects learning, mood, and memory
Norepinephrine and dopamine are excitatory neurotransmitters that are important in motivation, alertness, concentration and memory.

8. Parkinson’s Supplementation
S-methyl-L-cysteine (SMLC)
Helps reduce oxidation by promoting the methionine sulfoxide reuductases
Found in garlic, cabbage, and turnips
Tyrosine
Gets converted to Dopamine
CoQ10
R-alpha-lipoic acid and acetyl-L-carnitine
Helps produce Glutathione, which contains Sulfur and helps recycle antioxidants
Mucuna pruriens
Herb that can help produce dopamine
Vitamin E
Vitamin B complex
Selenium

9. Alzheimer's Supplementation
Tyrosine
Converts to Dopamine, which converts to noriepinephrine
suppress Aβ-induced production of cytokines and their phagocytosis of Aβ
S-adenosyl methionine
Found in almost every tissue in the body; helps production of neurotransmitters
Vitamin B6, B9, B12
Can lower levels of homocysteine
Huperzine
Improves cognition, behavior, ADL, and mood of Alzheimer disease patients
R-alpha-lipoic acid and acetyl-L-carnitine

10. Supplementation for Cognitive Decline
Omega 3 DHA
Curcumin
CoQ10
Astaxanthin
Regulates cytokines
Acetyl L-Carnitine
Protects against cell damage and increases muscle mass
Dimethlaminoethanol (DMAE)
Production of acetylcholine
Revesterol
Vitamin D3

11. Food to Help Boost Cognitive Ability
Blueberries
Lean meats
Pumpkin/ Sesame seeds
Almonds
Peanuts
Legumes
Apples
Bananas
Beets
Green Tea

12. Brain Exercises
We need to constantly stimulate our brains, after all the brain is a muscle as well.
Use your opposite hand to:
Brush your teeth
Use a mouse for the computer
Get dressed with your eyes closed
Physical exercise-research has constantly shown that exercise produces more neurons in the brain, thus making us smarter and raising our IQ
Spark: The Revolutionary New Science of Exercise and the Brain by Dr. John Ratey
Exercise in the morning
Yoga
Tai Chi
Learning to play a musical instrument
Painting or Drawing

13. Resources
_1_cognitive-decline-silent-strokes-stroke-program
Naturally

14. THANK YOU!! Dr. Jonathan Mendoza, DC RN Kyle Total Healthcare
Facebook.com/kyletotalhealthcare
Drdoza.wordpress.com