The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication Representative images of wt and mdi1 ovarioles stained.

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The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication Representative images of wt and mdi1 ovarioles stained for ATP‐S, illustrating mitochondrial morphology. Note that mitochondria progressively clump together in mid‐ to late‐stage egg chambers of mdi1 flies. Scale bars, 10 μm. Representative images wt and mdi1 eggs stained for ATP‐S, illustrating mitochondrial morphology. Scale bars, 100 μm. High‐mag images of wt and mdi1 eggs stained for ATP‐S. Scale bars, 20 μm. Note the clumping mitochondria in eggs produced by mdi1 flies. Data information: Arrowheads point to the mitochondria that normally associate with fusome in wt and mdi1 ovarioles. Arrows point to clumped mitochondria in mdi1 ovarioles and eggs. IF THIS IMAGE HAS BEEN PROVIDED BY OR IS OWNED BY A THIRD PARTY, AS INDICATED IN THE CAPTION LINE, THEN FURTHER PERMISSION MAY BE NEEDED BEFORE ANY FURTHER USE. PLEASE CONTACT WILEY'S PERMISSIONS DEPARTMENT ON PERMISSIONS@WILEY.COM OR USE THE RIGHTSLINK SERVICE BY CLICKING ON THE 'REQUEST PERMISSIONS' LINK ACCOMPANYING THIS ARTICLE. WILEY OR AUTHOR OWNED IMAGES MAY BE USED FOR NON-COMMERCIAL PURPOSES, SUBJECT TO PROPER CITATION OF THE ARTICLE, AUTHOR, AND PUBLISHER. EMBO J, Volume: 35, Issue: 10, Pages: 1045-1057, First published: 06 April 2016, DOI: (10.15252/embj.201592994)