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Details of the binding sites of tetracycline and edeine

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Presentation on theme: "Details of the binding sites of tetracycline and edeine"— Presentation transcript:

1 Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3
Details of the binding sites of tetracycline and edeine. All images show the σA weighted difference density at contour levels ranging from 3.2 to 2.2σ for tetracycline, and 3.2σ for both edeine and the RNA base pair induced upon its binding. (A) Stereo view of Tet‐1. (B) Mono view of Tet‐2. (C) Mono view of Tet‐3. (D) Stereo view of Tet‐4 and ‐6. (E) Left: stereo view of Tet‐5. Right: chemical structure of tetracycline. (F) Left: stereo view of the binding site of edeine. Right: chemical structure of edeine. IF THIS IMAGE HAS BEEN PROVIDED BY OR IS OWNED BY A THIRD PARTY, AS INDICATED IN THE CAPTION LINE, THEN FURTHER PERMISSION MAY BE NEEDED BEFORE ANY FURTHER USE. PLEASE CONTACT WILEY'S PERMISSIONS DEPARTMENT ON OR USE THE RIGHTSLINK SERVICE BY CLICKING ON THE 'REQUEST PERMISSIONS' LINK ACCOMPANYING THIS ARTICLE. WILEY OR AUTHOR OWNED IMAGES MAY BE USED FOR NON-COMMERCIAL PURPOSES, SUBJECT TO PROPER CITATION OF THE ARTICLE, AUTHOR, AND PUBLISHER. EMBO J, Volume: 20, Issue: 8, Pages: , First published: 17 April 2001, DOI: ( /emboj/ )

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