From: Using Alcohol as a Standard to Assess the Degree of Impairment Induced by Sedative and Analgesic Drugs Used in Ambulatory Surgery Anesthes. 1995;82(1):53-59.

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From: Using Alcohol as a Standard to Assess the Degree of Impairment Induced by Sedative and Analgesic Drugs Used in Ambulatory Surgery Anesthes. 1995;82(1):53-59. Figure Legend: Figure 1. Effects of 2 mg/70 kg midazolam (square), 70 mg/70 kg propofol (circle), and 50 micro gram/70 kg fentanyl (triangle) on DSST performance (top), short-term memory (middle), and VAS “sedated” ratings (bottom) relative to placebo (diamond) and 56 g/70 kg alcohol that produced a mean blood alcohol concentration of 0.11%(i.e., 15 min after injection). The alcohol effects are denoted by the shaded area in each of the graphs, with the mean being the center line and the outermost lines representing plus/minus 1 SEM. Closed symbols represent statistically significant differences from placebo at a given time. Asterisks represent drug effects that are both statistically significant from placebo and do not differ significantly from the alcohol effects that were associated with a blood alcohol concentration (BAC) of 0.11%. Date of download: 10/30/2017 Copyright © 2017 American Society of Anesthesiologists. All rights reserved.