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From: Isoflurane Modulation of Neuronal Nicotinic Acetylcholine Receptors Expressed in Human Embryonic Kidney Cells Anesthes. 2005;102(1):76-84. Figure Legend: Fig. 7. Concentration-response relationship for isoflurane to inhibit the activated receptors. A piezo switch was used to apply isoflurane with a complete solution exchange within 2 ms. ( A ) The concentration-dependent block by isoflurane of the current activated by 100 μm acetylcholine. ( B ) The dose-response relationship for isoflurane inhibition. ( C ) Onset and offset of block of acetylcholine currents by 84 μm and 280 μm isoflurane. Date of download: 12/18/2017 Copyright © 2017 American Society of Anesthesiologists. All rights reserved.
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