1. Neuromuscular Relaxants as Antagonists for M2and M3Muscarinic Receptors 
Anesthes. 1998;88(3):
Figure Legend:
Figure 1. Saturation radioligand binding of3H-QNB to M2(A) or M3(B) muscarinic receptors stably transfected in Chinese hamster ovary cells.3H-QNB (0.05–3 nM) was incubated for 2 h at room temperature with 40 micro gram of membranes prepared from Chinese hamster ovary cells overexpressing the M2(A) or M3(B) muscarinic receptor in the presence or absence of 2 micro Meter atropine. Saturation of specific binding was achieved over the range of sup 3 H-QNB concentrations used (n = 3). Values are mean +/- SEM. The insets show that representative Scatchard transformations of saturation binding allowed determination of receptor affinity for3H-QNB and quantity of total receptors.
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