1 Detecting & Responding 2 Unit 3 Biology Area of Study 2
2 Physical and Chemical Barriers to infection
3 Defence against infection: Plants
4 Defence against infection: Humans
5 Detecting ‘Self’ & ‘Non- self’ Molecules
6 Infection and Disease
7 Pathogens: Bacteria
8 Pathogens: Fungi, Yeasts, Protozoa
9 Pathogens: Arthropods & Worms
10 Pathogenic Agents: Viruses, viroids and Prions
11 Transmission of Pathogens
12 Recognition
13 Disease – Terminology 1 Infection - growth of organism within body of host Chronic disease - long-term infection Acute disease - infection occurs suddenly, is short term Parasite - organism living on or in another organism, gains benefit, provides nothing. Not necessarily pathogenic. Carrier -person lacking particular disease but host to transmittable causative agent. Host -organism or cell on or in which a specific parasite lives
14 Recognition Disease – Terminology 2 Host -second host necessary in addition to host for completion of life cycle Vector - insect or other animal transmitting pathogenic organism from host to host Virulence - degree to which an organism can cause disease Pathogen - organism able to cause disease in host
15 Recognition Disease – Terminology 3 Epidemic - many people in region develop specific infectious disease over short period Pandemic - people world-wide develop specific diseaseas it spreads from origin relatively quickly Antibiotic - naturally occurring substances that inhibit growth or destroy bacteria & other micro-organisms Designer drug - drug constructed to inhibit activity of pathogen by fitting into its active site
16 Immune Response
17 Immune System in Humans
18 Function of the immune System
19 Innate Immunity
20 Cells of Immune System
21 Non-specific response: Inflammation
22 Non-specific response: Blood Clotting
23 Non-specific response: Phagocytosis
24 Immune response: Complement
25 Specific Immunity
26 B Cells: Humoral Response
27 T Cells: Cell- Mediated Response
28 Antigens
29 Antibodies
30 Production of Antibodies
31 Antigen-Antibody Interactions
32 Disorders of the Immune Response
33 Failures of the Immune System
34 Acquired Immunity
35 Active & Passive Immunity
36 Active & Passive Immunity