1. of Cranberry seed extract together with
Benefits of Taking AstaCran®
The POWER
of Cranberry seed extract together with
the super-antioxidant AstaXanthin

2. Advantages of AstaCran®
AstaCran® has extremely good stability
NO harmful solvent residues
Flaxseed and fish oils have a very short shelf life
These oils actually become rancid in short time and can (in some cases) become carcinogenic
No other supplement provides such a balanced ratio of essential fatty acids
AstaCran ® is derived from highly-renewable and safe sources

3. Advantages of AstaCran®
Source of balanced EFA’s
Super Antioxidant
Aids in maintaining cardiovascular health
Aids with cholesterol management
Protects skin and eyes from photic injury
Reduce risk factors associated with macular degeneration
“Anti-Aging” properties via reduction of oxidative stress
Balanced EFA’s and super antioxidant in a single dose (Savings $$)

4. AstaCran® Cranberol™ Cranberry seed extract Zanthin™
Astaxanthin complex

5. Cranberries Vaccinium macrocarpon
Cranberol™
Cranberry seed extract
Cranberry seeds
Supercritical CO2 extraction method
NO harmful solvent residues
High amounts of Essential Fatty Acids (EFA’s)
Omega-3 and Omega-6
Also possesses antioxidants
High levels of Phytosterols
Cranberries Vaccinium macrocarpon

6. Cranberry Seed Extract
Super Critical CO2 extraction
Extraction performed under high
pressure using CO2 as a solvent
When extraction is complete, CO2 gas leaves NO residue (This may not be true with other commonly used solvents)
This is an exception, not the standard
Highly sustainable source of a balanced ratio of Essential Fatty Acids (EFAs)

7. Essential Fatty Acids
Polyunsaturated Fatty Acids (PUFAs) “double bond”
Omega-3 and Omega-6
Essential because your body does not produce them. Acquired from diet or food supplements
Nutritionists have found that a balanced Omega-6/Omega-3 ratio of 1:1 is best for optimal health

8. EFA’s – Omega-6 & Omega-3 The current western diet:
15:1 and higher ratio
Recommended dietary ratio:
Between 5:1 and 10:1
1:1 ratio in humans is ideal
The best supplemental source should have as close to a 1:1 ratio as possible

9. Omega-6 Linoleic acid (LA) Most commonly produced Essential
This converts in the body to gamma-Linolenic acid (GLA) and then to prostaglandins that help regulate inflammation and blood pressure, as well as heart functioning.
Linoleic acid (LA)
Most commonly produced Essential
Fatty Acid in agricultural seed oil production
Majority intake from vegetable oils
Highly unbalanced amounts of LA are bad because they promote inflammation, which can lead to many health problems
Primarily beneficial when in balance with Omega-3’s Alpha-Linoleic Acids (ALAs)

10. Omega-3 ά Linolenic acid (ALA) High concentrations of Omega-3
improves vitality of the skin
Absorption is enhanced when combined with Omega-6
As our diets have changed, Omega-3 consumption has decreased to a ratio that is associated with degenerative conditions
Omega-3 helps reduce LDL cholesterol

11. Other Sources Other EFA sources Fish and shellfish Flaxseed (linseed)
Canola oil, hemp oil, soya oil
Chia seeds, pumpkin seeds, sunflower seeds
Leafy vegetables and walnuts
AstaCran can replace ALL other supplemental EFA sources (BIG savings)

12. Cranberol™ Antioxidants
Tocopherols
Vitamin E family
Powerful antioxidant
Tocotrienols
Also a form of Vitamin E
40-60x stronger than
tocopherols as an antioxidant

13. What is an Antioxidant? An·ti·ox·i·dant
A substance (as beta-carotene or vitamin C) that inhibits oxidation or reactions promoted by oxygen, peroxides, or free radicals.
Merriam-Webster Online
It gives, takes, or traps an electron.

14. Phytosterols Phytosterols play an important role in
maintaining a healthy cholesterol level
Reduces cholesterol absorption in the intestines
Similar chemical structures that compete with cholesterol for absorption.
Significant for cardiovascular health
Beta-sitosterol
Helps reduce blood levels of cholesterol
Stigmasterol

15. Cholesterol Low Density Lipoproteins (LDL)
So called “Bad” cholesterol.
Transports cholesterol into the arteries.
High Density Lipoproteins (HDL)
So called “Good” cholesterol
Suspected to carry cholesterol from within* arteries to liver for redistribution or expulsion
*ath·er·o·ma - 1:  Fatty degeneration of the inner coat of the arteries
2:  An abnormal fatty deposit in an artery
Merriam-Webster Online

16. Cranberol™
Cranberol can aid and support a healthy cardiovascular system
Aid in maintaining healthy cholesterol levels
Aid in reduction of oxidative stress
Desirable source for a balanced ratio of EFA’s
Doesn’t turn rancid like many other sources of EFA’s

17. Zanthin® Astaxanthin complex Super-antioxidant
Prevents oxidative damage
418g Atlantic Salmon = 3mg of astaxanthin. (1 pound = grams)
Fish is becoming less desirable as a source for necessary compounds due to a concern over the rising levels of mercury, and various other heavy metals.

18. Source of Zanthin® Haematococcus microalgae Haematococcus pluvialis
Unicellular green algae
Found in Freshwater bodies
SPECIES
(3S,3’S)
(3R,3’R) & (3R,3’S)
(3R,3’R)
Yeast (Phaffia sp.)
---
<2%
>98%
Micro algae (Haematococcus)
100%
Synthetic Astaxanthin (Carophyll Pink La Roche)
25%
50%
Atlantic Salmon
78-85%
2-6%
12-17%(Schiedt et al 1981)cited in Foss 1984
Distribution of Astaxanthin stereo isomers in selected organisms (Bjerkeng1997)

19. Haematococcus Pluvialis
Potent source of astaxanthin
Highly renewable
Safe
Grown in a controlled environment

20. Other Sources Abundant in Nature (in water)
Found in Salmon, Trout, Crustaceans,
Crawfish,Pacific Cod, Scallops, Mackerel, Flounder, and other commercial seafood
Renewable

21. Astaxanthin Concentration
Species
Amount of Astaxanthin present per Kilogram
Atlantic Salmon
3 - 11mg
Sockeye Salmon mg
Rainbow Trout
1 - 13mg
Yeast (Phaffia sp.) mg
Algae (Haematococcus
pluvialis)
10, ,000mg

22. Zanthin® Astaxanthin Super-antioxidant Properties of Astaxanthin
Decreased DNA damage.
Arrests mitochondrial free radicals
Powerful Antioxidant
Crosses blood-retina barrier
Immune-modulatory activity
Provides anti-inflammatory activity
Increases strength and endurance
Protects eyes and skin from photic injury

23. ORAC – Oxygen Radical Absorbance Capacity
Antioxidant Studies
ORAC – Oxygen Radical Absorbance Capacity
AstaZanthin™ Standardized Extract
Natural Lycopene
Synthetic Astaxanthin
Natural alpha-tocopherol
Natural a-b Carotene mix
Natural Tocotrienols
Natural Lutein
Natural Beta Carotene
1.380
0.596
0.419
0.381
0.345
0.318
0.280
0.242
Anti Oxidant Studies
Naguib, Y., "Antioxidant Activities of Astaxanthin and Related Carotenoids,"Journal of Agricultural and Chemistry, v.48 (4), pp

24. Astaxanthin
Astaxanthin was times stronger than vitamin E in the lipid peroxidation of mitochondria membranes using the TBA method Inoue (1990)
Astaxanthin is 10 times stronger than zeaxanthin, lutein, beta-carotene and canthaxanthin
Astaxanthin is 100 times greater than alpha-tocopherol against active oxygen species in the thiobarbituric assay
Miki (1991)

25. Strength and Endurance
Fitness (submaximum load – Astrand method)
Strength/Explosivity (Wingate method of maximum effort)
Endurance (knee-bending technique)
Malmsted, C.L. Gustavsberg, Sweden
6 Month Treatment Pre-treatment standardized exercise tests/endurance (p<0.05)
Significant Improvement
in strength/endurance (p<0.05)
“Dietary Supplement with Astaxanthin-Rich Algal Meal Improves Muscle Endurance - A Double-blind Study on Male Students” N=40

26. Strength and Endurance
Increased Carotenoid content