1. Veterinary Jeopardy! Waterford Union High School

2. Rules Each team sends one person per turn. They cannot get help from their team First to “buzz” in gets 15 seconds to answer. If the first person to buzz cannot get the answer, the second team can buzz in. Once they buzz in, they too have 15 seconds. They also cannot get help. You either gain or lose points on each turn. If no team buzzes within 10 seconds, the question ends and the answer is given.

3. $100 $200 $300 $400 $500 Termin- ology Plasmid Resistance Mech’s of Resistance Pharm, Bio, None? Immune System Vaccines

4. Terminology This is the term for usage of a drug that is different from the manufacturers instructions and not prescribed by a medical professional. Off label usage

5. Terminology This is when directions prescribed by a medical professional differ from the drug’s original instructions. Extra-label usage

6. Terminology This is the term for when a pharmaceutical becomes ineffective against its intended pathogen due to overuse, abuse, or inappropriate use. Drug/Antibiotic Resistance

7. Terminology This is the term for a drug that is used to prevent a disease by using a weakened or killed version of the pathogen. Biological or vaccine

8. Terminology This is the term for a form of resistance that the bacteria acquires by random mutation. Chromosomal resistance.

9. Plasmid Resistance This is the form of plasmid resistance in which a virus transfers the gene for resistance Transduction

10. Plasmid Resistance The form of plasmid resistance in which a gene literally “jumps” out of the genome is known as… Transposons

11. Plasmid Resistance The form of plasmid resistance that involves the formation of and exchange of genetic material over a sex pilus is known as… Conjugation

12. Plasmid Resistance The form of plasmid resistance in which bacteria absorb genes remaining from a lysed bacteria would be… Transformation

13. Plasmid Resistance -What is a plasmid? -An acquired circular piece of DNA in a bacteria that is not part of its original DNA (“extra DNA”)

14. Mech’s of Resistance The mechanism of antibiotic resistance that would include the 3 rd membrane of gram negative bacteria would be… Decreased permeability Efflux Pumps Deactivating Enzymes Altered Target Site

15. Mech’s of Resistance The mechanism of antibiotic resistance in which a non-critical portion of the bacterial cell binds the antibiotic would be.. Decreased permeability Efflux Pumps Deactivating Enzymes Altered Target Site

16. Mech’s of Resistance The mechanism of antibiotic resistance in which the antibiotic is literally broken up is caused by… Decreased permeability Efflux Pumps Deactivating Enzymes Altered Target Site

17. Mech’s of Resistance The mechanism of antibiotic resistance in which the drug is forcibly removed from the inside of the bacteria would be… Decreased permeability Efflux Pumps Deactivating Enzymes Altered Target Site

18. Mech’s of Resistance Gram-negative bacteria always use this mechanism of antibiotic resistance Decreased permeability Efflux Pumps Deactivating Enzymes Altered Target Site

19. Pharm, Bio, None? This is used to prevent a disease and is not effective if you already have had the disease. Biological

20. Pharm, Bio, None? This is used to treat a disease and does not work to prevent a disease from occuring. Pharmaceutical

21. Pharm, Bio, None? Over-use of this can lead to drug resistance. Pharmaceutical

22. Pharm, Bio, None? These provide the most reliable and effective form of livestock health management. Biological

23. Pharm, Bio, None? These provide the most reliable and effective form of livestock health management. Biological

24. Immune System This is the term for the 3-14 days it takes for a sufficient amount of antibody to be produced to fight a disease Primary response

25. Immune System These immune cells reduce the amount of antigen needed to stimulate an immune response. Memory cells

26. Immune System This is the term for the quicker, more rapid response to a pathogen after immunity stimulates the production of memory cells. Secondary Response

27. Immune System These are the predator cells that kill pathogenic bacteria and viruses. T-lymphocytes (or Killer T Cells)

28. Immune System This is the kind of immunity created by having the disease or a vaccination Active Immunity

29. Vaccines These are the kind of vaccine that are made from a less-virulent form of the pathogen. Live Vaccine

30. Vaccines This is the term for a vaccine that is made from only the antigens of the formerly-living pathogen Killed Vaccine

31. Vaccines This is the term for a vaccine that is made from a weakened version of the virulent pathogen Modified Live Vaccine

32. Vaccines This is the term for a biological made from the blood of an immune animal that provides short-term passive immunity Antiserum

33. Miscellaneous This is the term for the biological that is made from the blood of an animal that produced antibodies to bacterial toxins. Antitoxin

34. FINAL JEOPARDY Who developed the first vaccine? Edward Jenner