1. Complex Structures and Functions of Carbohydrates
Monosaccharides- single sugars
Glucose C6H12O6
Fructose
Disaccharides- double sugars
Sucrose ( table sugar)
Polysaccharides- three or more monosaccharides
Macromolecule
Starch
Glycogen
Cellulose- provides structure for plants (humans cannot digest)

2. The Ring Glucose and other monosaccharides often form ring structures#5 #1
The ring forms when a hydrogen is transferred from the hydroxyl group on the #5 carbon to the oxygen of the carbonyl group on the #1 carbon.
This allows the #1 carbon to form a bond with the oxygen attached to the #5 carbon, completing the ring.

3. Give an example of a monosaccharide.
Give an example of a disaccharide.
Give an example of a polysaccharide.
What is the molecular formula for this
sugar, and how do you know it is a sugar?

4. Condensation Reactions and Hydrolysis
Two [or more] monosaccharides may be joined by dehydration synthesis to produce larger disaccharides and polysaccharides.
Dehydration means to take water out. When dehydration synthesis occurs, something is being built, while taking water out, or producing water as a product.
XOH + HZ à XZ + HOH
Dehydration synthesis is a typical condensation reaction.
The reverse reaction of breaking up polymers is accomplished by another chemical reaction known as hydrolysis.
Hydrolysis is simply the reverse of dehydration synthesis. You add water to a molecule to break it down.
X + H2O --> HX + OH
Glucose is a very common monosaccharide that is used for cellular respiration among other things. The names of most sugars end in –ose. The carbon skeletons of monosaccharides are usually 3-7 carbon atoms long. Glucose and fructose are hexoses (six-carbons long), pentoses have five carbons, and trioses have three carbons.

5. Two glucose molecules can be joined to produce a molecule of maltose [and a molecule of water].
A glycosidic link occurs when two monosaccharides are joined by dehydration synthesis.
A second disaccharide, the common table sugar known as sucrose, is produced by combining glucose and fructose.
If dehydration synthesis continues for a long time, a long and complex carbohydrate chain called a polysaccharide is formed.

6. Polysaccharides are produced by adding more monosaccharides to the chain. Some of the most important polysaccharides are made of long polymers of glucose.
What element can be found at each corner in the ring?
In glycogen, or animal starch, the glucose units are again joined to produce long chains, but side chains are linked to the main chain.

7. What process joins two monosaccharides together?
What type of reaction is dehydration synthesis?
When two monosaccharides are joined together, what are the products?
What reaction breaks down polysaccharides?
What are the reactants in hydrolysis?
Where does a glycosidic link form?
Dehydration synthesis; condensation reaction; disaccharide, and water; hydrolysis; forms between two monosaccharides

8. Storage Polysaccharides
Chloroplast
Starch
Amylose
Amylopectin
1 m
Starch
Is a polymer consisting entirely of glucose monomers
Is the major storage form of glucose in plants
Plastids are organelles such as chloroplasts, which store starch.

9. Animals in turn eat plant materials and products.
Glycogen is the storage form of glucose in animals and humans which is analogous to the starch in plants. Glycogen is synthesized and stored mainly in the liver and the muscles
Plants make glucose and cellulose through the photosynthesis processes, and store starch primarily in their roots.
Mitochondria
Giycogen granules
Animals in turn eat plant materials and products.
0.5 m
Digestion is a form of hydrolysis where the starch is broken down into the various monosaccharides. A major product is glucose, which can be used immediately for metabolism to make energy, through the process of cellular respiration.
Glycogen
The glucose that is not used immediately is converted in the liver and muscles into glycogen for storage. Any glucose in excess of the needs for energy and storage as glycogen is converted to fat.

10. Where is most starch stored in plants?
What are plastids?
What is animal starch called, and where is it produced and stored mainly?
What process in animals can be likened to hydrolysis, and what is the main product of hydrolysis?
What is that glucose used for?
What happens if glucose exceeds energy and storage needs?
Roots; organelles like chloroplasts which produce and store small amounts of starch; glycogen, liver and muscles; digestion, glucose; cellular respiration, and energy; converted into fat

11. Another polysaccharide, cellulose, has its glucose units joined together, however, alternating glucose units are 'flip-flopped'.
Changes in the bond configuration cause changes in the final shape and function of the molecules.
Cellulose is found in plant cells, and forms the structurally strong  framework in the cell wall. It’s lattice-like structure makes it very strong indeed.

12. Cellulose is difficult to digest
Cows and other herbivores have microbes in their stomachs to facilitate this process
Humans do not!

13. Chitin, another important structural polysaccharide
Is found in the exoskeleton of arthropods
Can be used as surgical thread
(a) The structure of the
chitin monomer. O
CH2OH OH H NH C
CH3
(b) Chitin forms the exoskeleton
of arthropods. This cicada
is molting, shedding its old
exoskeleton and emerging
in adult form.
(c) Chitin is used to make a
strong and flexible surgical
thread that decomposes after
the wound or incision heals.

14. What is the structural significance of cellulose in plants?
How do herbivores digest cellulose?
What element can be found in the polysaccharide chitin, that isn’t in other carbohydrates?
Very strong for cell walls; with the help of bacteria; nitrogen

15. Complex Structures and Functions of Lipids
Fats and oils are made from two kinds of molecules:
Complex Structures and Functions of Lipids
Do you remember what fats are composed of?
glycerol (a type of alcohol)…and three
fatty acids joined to it by dehydration synthesis.
Since there are three fatty acids attached, these are known as triglycerides.
The main distinction between fats and oils is whether they’re solid or liquid at room temperature, and this is based on differences in the structures of the fatty acids they contain.

16. The Structure of fatty acids:
The “tail” of a fatty acid is a long hydrocarbon chain, making it hydrophobic.
Hydrophobic means fear of water…so the tail end of a fatty acid is nonpolar, and will not associate with water at all.
The “head” of the molecule is a carboxyl group which is hydrophilic.
Hydrophilic means water friendly…so the head end of a fatty acid will readily associate with water.
Glycerol Backbone
Fatty acids are the main component of soap, where their tails are soluble in oily dirt and their heads are soluble in water to emulsify and wash away the oily dirt. However, when the head end is attached to glycerol to form a fat, that whole molecule is hydrophobic.

17. What process joins the fatty acids to the glycerol to make fat?
The tail of a fatty acid is a nonpolar hydrocarbon. What word describes its association with water?
The head end of a fatty acid has a carboxyl group which is hydrophyllic. Describe its association with water.
What part of the fat makes the whole molecule hydrophobic?
Dehydration synthesis; hydrophobic; it freely associates with water; the glycerol backbone.

18. Saturated...or Unsaturated...that is the question
Saturated fatty acids
straight molecules
Generally solid at room temperature
Butter, lard, grease from cooked meats
Contain no double bonds between carbons
Unsaturated fatty acids
Some carbon atoms linked by a “double’ covalent bond
Generally liquid at room temperature
EX: olive oil, fish oils
Hydrogenated vegetable oils contain naturally unsaturated fatty acids that have been saturated artificially (with hydrogen) and are generally solid at room temperature
EX: margarine, vegetable shortening

19. How do you know the fat on this meat is a saturated fat?
How are the carbon bonds between saturated and unsaturated fats different?
Describe how hydrogenated unsaturated fatty acids are different from natural unsaturated fatty acids.

20. Phospholipids
Phospholipids are made from
glycerol
two fatty acids, and (in place of the third fatty acid)
The hydrocarbon tails of the fatty acids are still hydrophobic, but the phosphate group end of the molecule is hydrophilic because of the oxygens with all of their pairs of unshared electrons.
a phosphate group with some other molecule attached to its other end.
This means that phospholipids are soluble in both water and oil.
This becomes especially important as we learn about cells, and the structure of their membranes.

21. (a) Structural formula (b) Space-filling model
Structure of the
Phospholipid Bilayer
Our cell membranes are made mostly of phospholipids arranged in a double layer with the tails of the fatty acids from both layers “inside” (facing toward each other) and the heads facing “out” (toward the watery environment) on both surfaces. This protects the cell from many molecules moving across the membrane.
CH2 O P CH C
Phosphate
Glycerol
(a) Structural formula
(b) Space-filling model
Fatty acids
(c) Phospholipid
symbol
Hydrophobic tails
Hydrophilic
head
Hydrophobic
tails –
Hydrophilic head
Choline +
Figure 5.13
N(CH3)3
Inside of cell
Outside of cell

22. How are phospholipids different from other lipids, structurally?
What is the significance of the phosphate group on the phospholipid?
Why are phospholipids important in the structure of our cell membranes?
Phosphate group instead of 3rd fatty acid; makes it soluble in both fat and water; because they protect the interior of the cell from molecular movement in a disorganized fashion.

23. Steroids...otherwise known as Cholesterol
Cholesterol is not a “bad guy!” Our bodies make about 2 g of cholesterol per day, and that makes up about 85% of blood cholesterol, while only about 15% comes from dietary sources.
Cholesterol is the precursor to our sex hormones and
Steroids may be recognized by their skeleton, consisting of three fused six-membered and one five-membered ring
Vitamin D
Vitamin D is formed by the action of UV light in sunlight on cholesterol molecules that have “risen” to near the surface of the skin.
Our cell membranes contain a lot of cholesterol (in between the phospholipids) to help keep them “fluid” even when our cells are exposed to cooler temperatures.

24. Waxes Waxes are widely distributed in nature.
Cuticle
Ocotillo Cacti
The leaves and fruits of many plants have waxy coatings, which may protect them from dehydration and small predators.
Cuticle
The feathers of birds and the fur of some animals have similar coatings which serve as a water repellent.

25. Lipoproteins are clusters of proteins and lipids all tangled up together. These act as a means of carrying lipids, including cholesterol, around in our blood.
There are two main categories of lipoproteins distinguished by how compact/dense they are.
LDL or low density lipoprotein is the “bad guy,” being associated with deposition of “cholesterol” on the walls of someone’s arteries.
HDL or high density lipoprotein is the “good guy,” being associated with carrying “cholesterol” out of the blood system, and is more dense/more compact than LDL.

26. Pigments Xanthophylls and melanins
Many plant pigments, such as anthocyanins, chlorophylls A and B, carotenoids and xanthophylls are lipids.
Some lipid pigments can also appear in animals, like cichlids…and people.
Xanthophylls and melanins

27. Which is the “bad guy”, LDL or HDL, and why?
What lipid plays a key role in the “fluidity” of the cell membranes?