1. Applied Research and Innovation Activities A.Olshevskiy, 107th Session of JINR Scientific Council 18 February 2010

2. Applied Research and Innovation Activities General Framework and Partnership Technology Transfer Center JINR innovation projects Summary

3. General Agreement on Collaboration Moscow 13 February 2009 JINR and Kurchatov Institute Signed by M.V.Kovalchuk, Director of the Russian Scientific Centre - Kurchatov Institute, and A.N.Sissakian, Director of the Joint Institute for Nuclear Research, and aimed at consolidation of intellectual potential and establishment of the International Nanotechnology Innovation Centre of CIS countries on the basis of JINR and Kurchatov Institute with employment of the possibilities of the Special Economic Zone in Dubna

4. JINR and Rosnano Established Collaboration

5. Special Economic Zone at Dubna JINR Projects: SEZ Residents  Dubna-Sistema Managing Company (OJSC)  DViN (Ltd)  CYCLONE (Ltd)  InterGrafika (Ltd)  INNA (Ltd)  Scientific Production Center ASPECT (CJSC)  VNITEP Plus (Ltd)  NANO KASKAD (CJSC)  Scientific Production Association Vostok (Ltd)

6.  Regional Venture Foundation managed by Troika-Dialog  VTB-Assets Management A team of high-skilled specialists takes part in establishment of the centre. JINR actively implements programmes of private- intergovernmental partnership with the world’s leading manufacturers of products in particular areas (IBA, Belgium; Vacuum Praha, Czech Rep.; IST, Germany; Canberra Industries, the United States; etc.) and with Russian and foreign investment and venture companies. JINR Projects and Business Partners Agreement on Strategic Partnership  JSFC Sistema (2004)  JSFC Sistema (2004)

7. Dubna Nanocentre Project, spin-off JINR Anchor participants Internal demand for services Trackpore Technology Interlab INNA Machine time Placement and maintenance of equipment Nanocentre II. NIIPA, DMZ, ERA, Equipment Machine time SEZ Strategic customer RTI Business incubator in SEZ $ $ $ $ $ $ of spin off sales services options Building Nanocentre Management Company Services, work, technologies, product Programme committe management quoting Market customers m2m2 Startup companies RVK seed investment foundation Equipment on the basis of anchor participants (Equipment =avaitable+ ROSNANO)

8. DirectionsIon Radiation Electronic components, nano composites Biology Nanostructures: analysis –metrology – certification Nanotechnology in composite industry Technology and Competence Radiation-ion technologies of polimeric materials; Track electronic techologies; Ion implantation Radiation hardness tests Colloid synthesis of nano-particles: quantum dots, composites, functional elements and materials, Development and integration of detector systems equipment on their basis Nano- and Bio- technologies Neutron difractometry at the IBR; Electron microscopy; Spectroscopy X- ray analysis; Elemental analysis Optimization of technology; Pilot production; Tests; Certifications ParticipantsJINR (FLNR);JINR (DLNP), Institute of applied acoustics, INNA, SILA InterlabJINR (FLNP); ERA, Inst. of applied acoustics APATEK Dubna Nanocenter. Technologic directions

9. Nanocenter equipment installed at JINR JINR in Dubna Nanocentre Rosnano Transfer Technology Centre(ТТC) (Funds ~ 140 mln. rubles) JINR Preserves its equipment installs and uses ROSNANO equipment ; JINR has 50% operation time quote Equipment purchased by Rosnano ~ 450 mln. rub Projects: «Radiation-ion technologies» «Detectors». JINR equipment JINR, RTI-Sistema, IT, Insider Funding Beam time Financial resources Projects: Membranes; TEST Heat conductors; Composite on basis of track membranes; DETECTORS: МAPD; GaAs pixel detectors

10. Ion Track Technology Irradiation of Polymer Foils with Heavy Ions Etching of the Illuminated Foil Ion Track Blind Hole FoilsIon Track Membrane Size Comparision – a Human Hair and Micropores in an Ion Track Foil

11. Development and tests of pixel semiconductor detectors GaAs pixel detectors Micropixel Avalanche Photo Diodes

12. APPLIED RESEARCHES WITH NEUTRONS  Biomonitoring of atmospheric deposition of heavy metals and other elements (Project REGATA)  Control of quality and safety of foodstuffs, grown in industrially contaminated areas of RF and South Africa (grant of SA)  Assessment of different ecosystems and their impact on human health  Biotechnologies: development of new pharmaceuticals and cleaning the environment from toxic elements (biosorption)  NAA for the technological process of synthesis of diamonds and NB (boron nitride)  Analysis of archaeological and museum objects from Russian and other countries  NAA for decommissioning of Nuclear Power Plants and utilization of industrial wastes. Life SciencesMaterial Science

13. DViN Project Explosives and drugs detector on the basis of portable 14-MeV neutron generator with the built-in silicon α detector,  detectors (BGO) and identification system based on the neural network method Stationary explosives identification system Stationary explosives and drugs identification system Portable explosives detector

14. Proton Therapy at Phasotron Proton Therapy at Phasotron YearNo of accelerator runs No of patients treated 199923 2000 436 2001 549 2002 434 2003 684 2004690 2005124 2006Fire accident---- 2007784 2008687 20097106 Total48595 Diseases treated Meningiomas – 112 pts Chordomas, chordosarkomas – 19 pts Gliomas – 33 pts Acoustic Neurinomas – 7 pts Astrocytomas – 24 Paragangliomas – 5 pts Pituitary Adenomas – 17 pts AVMs – 60 pts Brain and other metastasis – 53 pts Other head and neck tumors – 134 pts Melanomas – 7 pts Skin diseases – 42 pts Carcinoma metastasis of the lung – 9 pts Breast cancer – 44 pts Prostate Adenomas – 1 pt Sarcomas – 9 pts Other – 19 pts

15. Development of hadron therapy equipment 1) Projects in ROSNANO: а) ID1143: Centre for Nanotechnologies in Nuclear Medicine б) ID1142: Centre for Production of High-Technology Equipment for Nuclear Medicine and Nanoindustry Specialized assembly and test centre constructed 2) Pilot Project of the Nuclear Medicine Centre for Russian oncology clinics Nuclear Medicine Center Project Assembly and test centre

16. Development of accelerator technique A project of the C400 superconducting cyclotron for particle energy 400 MeV/n (С6+, He2+) and proton energy 265 MeV is developed in cooperation with IBA. It is planned to be built at GANIL (France) FLNR Cyclotrons design and production for Member States (Kazakhstan, Slovakia) and innovation companies (Nanocascade project with Rosnano) DLNP has developed in cooperation with IBA С235-V3 proton cyclotron for proton therapy and С400 superconducting cyclotron for carbon therapy

17. NANOGRID Such a distributed computational system will be created with the key- participation of RSC “Kurchatov Institute, Moscow State University and Joint Institute for Nuclear Research JINR is actively involved in a number of European, Russian and Regional GRID projects aimed at providing the global infrastructure for fundamental and applied research: WLCG: (Worldwide LHC Computing GRID) EGEE: (The Enabling Grids for E-sciencE) RDIG: Russian Data Intensive GRID СКИФ-ГРИД Дубна-ГРИД

18. Summary Wide program of applied research complements the fundamental investigations performed at JINR The innovation policy of JINR is based on the use of its unique technology offers, services and R&D opportunities Partnership in innovation activities should be extended especially taking into account requests of JINR Member States