DrTorabi Kerman Dental School
MIXED ODONTOGENIC TUMORS Proliferating odontogenic epithelium in a cellular ectomesenchyme Varying degree of inductive effect enamel and dentin
Ameloblastic fibroma True mixed tumor May be early developing stage of odontoma
Clinical features Younger patients Slightly more common in males Asymptomatic Larger :swelling 70%posterior mandible
Radiographic features Radiolucent: multilocular or unilocular 75% with an unerupted tooth
Histopathologic features
Treatment and prognosis Conservative surgery Recurrence rate:0-18% in some series43.5% More aggressive surgery for recurrent lesions
Ameloblastic fibro-odontoma Ameloblastic fibroma +enamel and dentin Exhibiting progressive growth
Clinical features In children mean 10 years Posterior of jaws Male =females asymptomatic
Radiographic feature Well defined radiolucent, unilocular, Calcified material (radiodensity like tooth structure) Unerupted teeth
histopathology
Treatment and prognosis Conservative curretage Exellent
Ameloblatic fibrosarcoma Mean 27.5 years 80%in mandible male> female Pain and swelling rapid clinical growth
Ill-defined radiolucency
histopathology
Treatment and prognosis Radical surgical excision Locally aggressive 20%of these patients will succumb to their tumor
odontoma The most common odontogenic tumor Prevalence >other odontogenic is Hamartoma Compound>& complex Compound : multiple,small tooth-like Complex :no anatomic shape
Clinical features First 2 decade Mean age14 Asymptomatic Large odontoma up to6 cm Maxilla>mandible Compound more in anterior maxilla,compound in posterior early:Radiolucent with rim radioopaque Developed :radioopaue
histopathology Compound :multiple structures like tooth :Enamel matrix, pulp tissue, Complex :mature tubular dentin,odontogenic epithelium,cementum May be :odontogenic cyst
Tumors of odontogenic ectomesenchyme Odntogenic myxoma: Young adults Mean:25-30 No sex predilection Mandible> Small :no symptomatic Large :painless expansion Sometimes :rapid expansion accumulation myxoid ground substance
Radiographic features Unilocular or multilocular Displaced or resorption of teeth Irregular or scalloped margin Step ladder Soap bubble
histopathology Haphazardly arranged stellate, spindle shape, round Loose myxoid stroma Hyaluronic acid,chodroitin sulfate Cells:vimentin
Treatment and prognosis Small : curettage and periodic evaluation for at least5 years Large :extensive resection Recurrence :25% Myxosarcoma :no distant metastases
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