1. Oral Biology 5301 Bone growth and development Bone biology
Educational objectives
Exposure to basic concepts of bone biology
Correlation of basic bone biology to clinical treatment
Special considerations / implications of bone biology to dentistry

2. Clinical Correlates of Bone Growth and Development
Facial skeletal development
Maxillary development
Mandibular development

5. Clinical Correlates of Bone Growth and Development
Effect of congenital anomalies on facial growth and development
Effect of surgical correction of congenital anomalies on facial growth and development
Tooth development and retention influence on alveolar bone levels

6. Clincal Correlates of Bone Growth and Development
Orthodontic tooth movement
Bone healing following tooth extraction
Bone response to alloplastic materials
Bone healing in approximation of dental implants

7. Clinical Correlates of Bone Growth and Development
Bone grafting to treat dentoalveolar defects
Bone grafting to treat discontinuity defects
Fracture healing

8. Cellular Growth Hypertrophy Hyperplasia
Secretion of extracellular material
Interstitial growth

9. Embryologic Type of Bone
Endochondral
Intramembranous

37. Functional Matrix Theory of Growth
“Growth of the face occurs as a response to the functional need and is mediated by the soft tissue in which the bone is embedded”
Soft tissues grow, bone and cartilage react

38. Growth Control Bone is the determinant of its own growth
Cartilage is the determinant of bone growth
Soft tissue matrix is the determinant of growth
All are controlled genetically

44. Orthodontic Tooth Movement
Bone apposition and resorption
Effects on the pulp
Effects on the PDL
Effects on the tooth root

47. Effects of Periosteum Provision of undifferentiated mesechymal cells
Envelope to limit/regulate bone apposition

48. Introduction 10 y.o. female 12/98
CC:
Noticed swelling in face on left side for two weeks
HPI:
Facial swelling
Left lower lip “tingles”
No pain or change in bite

49. Examination Left lower facial swelling, without thrill/bruit
Lower vestibular swelling, L>R
No abnormal tooth mobility
Teeth vital with EPT
CN II-XII grossly intact

50. Assessment Problem list: Diff. Dx: Multilocular radiolucent lesion
Teeth vital without resorption, displacement, or mobility
Apparent cortical expansion
Diff. Dx:
Central Giant Cell Lesion
Ameloblastomic Fibroodontoma
Ameloblastoma

51. Treatment Plan Impressions for splint fabrication
Screening labs Ca, alk phos, PTH
All WNL
CT of mandible:
Multilocular radiolucents, from infer border to encompass tooth roots superiorly
Buccal and lingual cortices intact, although expansion present
Incisional bx

89. Facial Growth and Development
15 year old man
Congenital cleft lip and palate
29 surgeries to nose and lip
Significant malocclusion
Status post facial skeletal growth
Masticatory insufficiency

143. Facial Growth and Development
4 year old boy with jaw immobility
Mother concerned about failure to thrive and ability to receive dental care
Anterior open bite
Etiology unknown

165. Facial Growth and Development
7 year old boy
Condylar neoplasm resected as infant (age 2) and recurrence treated age 4
Concerns about facial growth and development