Pathology Lap Pictures and Explanation POD II BLOCK Abdullah Al Garni
Prostate gland, nodular hyperplasia تــــضخــم غـــدة الـــبروســـتاتا ( الموثة )
well-circumscribed nodules
hyperplastic glands With two layers well-circumscribed nodules margin the stroma
Breast, Fibroadenoma ســــرطــــان الثــــــدي
fibroadenomanormal breast tissuewell-demarcated border
Large irregularly shaped glandular spacesfibrous stroma
columnar epithelium Delicate stroma
Breast, Invasive ductal carcinoma ســـــرطان الـــــثدي
duct-like spacesfibrous stroma
duct-like spacesfibrous stroma
Non-neoplastic ductsInvading tumor cells Fat Stroma
Tumor cells
Invasive malignant glands
Invasive squamous cell carcinoma EXAMPLE: Bronchous ســـرطـــان القصبات الهوائية
central areas of keratinization
intercellular bridges the large hyperchromatic nuclei
Lung, Metastatic Carcinoma ســـــرطان الـرئة
The lung tissue has been replaced by large sheets of malignant cells The sheets is formed of pleomorphic cells with hyperchromatic nuclei There is also extensive necrosis The characteristic architecture of the residual normal lung can be seen.
Lipoma
mature white fat cellsThe nucleus
Schwannoma
The tumor shows a mixture of two growth patterns: -In the Antoni A pattern of growth, elongated cells with cytoplasmic processes are arranged in fascicles in areas of moderate to high cellularity with little stromal matrix. The nuclear palisading can be seen. - In the Antoni B pattern of growth, the tumor is less densely cellular with a loose meshwork of cells along with microcysts and myxoid changes. In both areas, the cytology of the individual cells is similar, with elongated cell shape and regular oval nuclei A A B B
Black arrow: Antoni A ; blue arrow: Antoni B
Bone, osteosarcoma ســـــرطان العـــظـــم
Spicules of tumor bone malignant osteoblasts that have produced spicules of bone surrounded by osteoid matrix (( characteristic of osteosarcomas)) External information
Mitosis
eosinophilic osteoid
Uterus, leiomyosarcoma ســـــرطان الــــرحم
high cellularity
High (N/C ratio) enlarged nuclei
Heart, acute myocardial infarction احتشاء عضلة القلب
coagulative necrosis (SCAR)
neutrophils
Coagulative necrosis Granulation tissue
Myocardial infarct, old احتشاء عضلة القلب, كبار السن
(SCAR) fibroblasts
Pulmonary edema تورم الرئة
Congested alveolar septa Intra-alveolar transudate