NCI Center for Global Health Jo Anne Zujewski, M.D. September 11, 2014 Dar es Salaam, Tanzania

2 Global Cancer Burden Cancer is a global epidemic and a leading cause of death worldwide, accounting for 7.6 million deaths or around 13% of all deaths in Worldwide, cancer now causes more deaths than HIV/AIDS, tuberculosis, and malaria combined. More than 70% of all cancer deaths occur in low- and middle-income countries.

This is for title This is for text Center for Global Health At-a-Glance The NCI Center for Global Health (CGH) was established in 2011 to: o Support NCI’s goal to advance global cancer research o Build expertise and leverage resources across nations to address the challenges of cancer o Reduce cancer deaths worldwide Center Director: Dr. Edward Trimble CGH collaborates with: U.S. government agencies Foreign governments Non-governmental organizations (NGOs) Pharmaceutical and biotechnology companies CGH and the Fogarty International Center (FIC) of the National Institutes of Health (NIH), which seeks to advance the mission of NIH internationally, work together closely to coordinate international partnerships and activities 3

This is for title This is for text CGH Vision and Mission Vision The vision of NCI’s Center for Global Health is to be a catalyst for reducing the global cancer burden through coordination, collaboration, and communication with a diverse range of international stakeholders. Mission The mission of NCI’s Center for Global Health is to create sustainable international partnerships, support programs that address global gaps in research and scientific training, and disseminate information and best practices that drive improvements in cancer research and cancer control. 4

This is for title This is for text CGH Strategic Priorities Supporting Cancer Research and Cancer Control Planning Creating and Sustaining Partnerships Monitoring Research Efforts Catalyzing Information Dissemination and Capacity Building

This is for title This is for text CGH Global Footprint

This is for title This is for text Women’s Cancer Program Goal: To advance local and global initiatives to prevent, diagnose, and treat women’s cancer by facilitating the development of a comprehensive cancer program and needed infrastructure Focus Areas: 1.Cultivating international partnerships in region 2.Providing technical assistance in breast and cervical cancer control efforts 3.Facilitating local training and research activities 4.Survivorship 5.Stigma 7

Source: GLOBOCAN 2008 via the American Cancer Society

Incidence Mortality 1.4 million cases in % of all cancers 19.3/100,000 women in East Africa 89.7/100,000 women in Western Europe 458,400 breast cancer deaths

Science, 2011 Cancer Survival Gap Breast Cancer Cervical Cancer

Stigma Cancer, and especially reproductive cancers, add a layer of discrimination onto gender, ethnicity, and poverty. Felicia Knaul, Director, Harvard Global Equity Initiative

Cancer Control Plan: Partnerships Basic and Clinical Research Education and Awareness Medical practice Cancer Control Plan Government Organizations. Academic Centers Research organizations NGO’s International Organizations Pharmaceutical and Biotechnology

Cancer Control Plan Awareness – Cancer is a critical health issue – Majority of cancer deaths in women occur in low-middle income countries, not among the rich Prevention – Common risk factors-tobacco use, unhealthy diet, excessive alcohol consumption and lack of physical activity Diagnosis: – Priority for early detection and diagnosis when cancer is at a treatable and potentially curable stage Treatment – access to affordable, effective drugs and vaccines, and to palliative care

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