 Aseptic conditions are conditions that ensure prevention of contamination of equipment, facilities, source of raw materials, intermediate products of viable micro-organisms and mechanical portions to ensure the sterility of the ready products. Production of drugs in aseptic conditions in pharmacies is carried out in special "clean" rooms, where air purity is standardized for content of microbes and mechanical parts.

Prepared in aseptic conditions, because at high temperatures they are destruct (barbital sodium, hexamethylenetetramine, barbamil, adrenaline hydrochloride, apomorphine hydrochloride, eufilin etc.) The solvent, filter material and tableware sterilized. The amount of water for injection at a concentration of drugs more than 3% is calculated taking into account increase factors. Ready solution released with the label "Made aseptically.

 As a general rule preparation of sterile solutions prepared solution of all stable at high temperatures substances, sterilize it, cool and add termolabile- unstable at high temperatures substance in aseptic conditions.

When heated, many of suspensions observed coarsening of the dispersed phase, which hinders their passage through a syringe needle. In this regard they are prepared in aseptic conditions in a sterile mortar from the sterilized ingredients. Therefore suspension for injections prepare, usually, with sterile powders (if they are stable at high temperatures), immediately before entering into the dosage form (in aseptic conditions) Way of introduction of suspensions for injection is only intramuscular.

 Sterilize separately all the components and mixed under aseptic conditions in sterile mortar by the rule of Deryagin. The ready suspension can not be sterilized because conglomerates are formed.  After prescription write- Addita aseptice!

Rp.: Streptocidi 6,0 Olei Persicorum 30,0 Sterilisa! Misce. Da. Signa. For intramuscular injection.

 In a dry bottle for dispensing filtered 30.0 peach oil and sterilized at 180°C 30 minutes (at 200 °C - 15 minutes or in an autoclave at 120 °C - 2 hours).

 In a sterile mortar aseptically grind streptocide 6.0 (sterilized at 150 ° C for 1 hour), first with 30 drops of 95% ethyl alcohol and then by the rule Deryagin with 3.0 oil to a maximum degree of fineness. Gradually add remaining peach oil. The drug is dispense from the label "For injection," "Shake before use", "Made aseptically”.

Date № prescription Streptocidi sterile 6,0 Olei Persicorum sterile 30,0 Addita aseptice Prepared Chacked