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Non-sterile compounding

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Presentation on theme: "Non-sterile compounding"— Presentation transcript:

1 Non-sterile compounding
PTCE Practice Questions

2 Question 1 Which of the following establishes standards of quality, strength, purity, packaging, and labeling for compounded medications? USP-NF FDA ASHP DEA

3 Question 1 Which of the following establishes standards of quality, strength, purity, packaging, and labeling for compounded medications? USP-NF FDA ASHP DEA

4 Question 2 The storage temperature definition for a freezer is
-30°C to 0°C -20°C to -10°C 8°C to 15°C 30°C to 40°C

5 Question 2 The storage temperature definition for a freezer is
2°C to 8°C- Cold -20°C to -10°C - Freezer 8°C to 15°C - Cool 30°C to 40°C - Warm

6 Question 3 The minimum weighable quantity for a class III balance is
120 mg 500 mL 120 mL 500 mg

7 Question 3 The minimum weighable quantity for a class III balance is
120 mg 500 mL 120 mL 500 mg Check your units! You can immediately get rid of “ml” answers!

8 Question 4 Metric weights used for weighing ingredients using a class III balance should be handled with Water Fingers Forceps oil

9 Question 4 Metric weights used for weighing ingredients using a class III balance should be handled with Water Fingers Forceps oil

10 Question 5 Quantities less than 120 mg may be measured using a/an
Arrest Aliquot Calibration Sensitivity

11 Question 5 Quantities less than 120 mg may be measured using a/an
Arrest Aliquot Calibration Sensitivity Aliquot- a portion of the whole

12 Question 6 ______________ is the term for triturating a powdered drug with a solvent in which it is insoluble to reduce it’s particle size Suspension Trituration Emulsion Levigation

13 Question 6 ______________ is the term for triturating a powdered drug with a solvent in which it is insoluble to reduce it’s particle size Suspension A 2 phase system with uniform dispersion of finely divided solid drug particles in a continuous phase of solid, liquid, or gas in which the drug has minimum solubility. Trituration Using a mortar and pestle to grind a drug solid to reduce particle size, or to mix two or more solids together Emulsion Mixture of 2 or more liquids that are normally immiscible Levigation The trituration of a powdered drug with a solvent in which the drug is insoluble to reduce the particle size of the drug

14 Question 7 The appropriate flavoring for a metallic tasting drug is
Mint Orange Cinnamon Anise

15 Question 7 The appropriate flavoring for a metallic tasting drug is
Mint Orange Cinnamon Anise

16 Question 7 Taste Flavor Salty
Cinnamon, Raspeberry, Orange, Butterscotch Sweet Fruit, berry, vanilla Bitter Cocoa, chocolate, mint, cherry, walnut Sour/Acid Fruit, citrus, cherry Oily Wintergreen, peppermint, lemon, anise Metallic Mint, Marshallow

17 Question 8 A two-phase system consisting of a finely divided solid dispersed in a liquid is a/an Suspension Emulsion Solution Trituration

18 Question 8 A two-phase system consisting of a finely divided solid dispersed in a liquid is a/an Suspension Formulation in which the drug does not completely dissolve in the liquid Emulsion Mixture of 2 liquids that do not mix with eat other; one liquid is dispersed through the other by mixing and using an emulsifier for stability. Solution A clear liquid made up of one or more substances dissolved in a solvent Trituration The process of grinding powders to reduce particle size

19 Question 9 ____________ are thickening agents used in the preparation of suspensions Electrolytes Preservatives Flocculating agents Suspending agents

20 Question 9 ____________ are thickening agents used in the preparation of suspensions Electrolytes Substances that in solution form ions that conduct an electrical current Preservatives A substance used to preserve materials against decay Flocculating agents Electrolytes used in the prepartion of suspensions to form particles that can be easily redispersed Suspending agents A substance added to promote particle suspension or dispersion

21 Question 10 The punch method is used to prepare Tablets Capsules
Suppositories Emulsions

22 Question 10 The punch method is used to prepare Tablets Capsules
Suppositories Emulsions

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24 Question 11 Which of the following is not a characteristic of an absorption base? Anhydrous Difficult to spread Nongreasy Nonwashable

25 Question 11 Which of the following is not a characteristic of an absorption base? Anhydrous Difficult to spread Nongreasy Nonwashable Which of these things is not like the other? (of a substance, especially a crystalline compound) containing no water- anhydrous

26 Question 12 If a pharmacy technician is using the continental (dry gum) method, what would he or she be compounding? Capsules Emulsions Suppositories Syrups

27 Question 12 If a pharmacy technician is using the continental (dry gum) method, what would he or she be compounding? Capsules Emulsions Suppositories Syrups An emulsion is a mixture of two or more liquids that are normally immiscible (unmixable or unblendable). May be compounded by dry gum, wet gum, or emulsion method

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29 Question 13 What technique is used in mixing two ingredients of unequal quantities? Blending Geometric dilution Levigation Spatulation

30 Question 13 What technique is used in mixing two ingredients of unequal quantities? Blending An act of combining two substances Geometric dilution Levigation Trituration of a powder drug with a solvent in which the drug is insoluble with the solvent Trituration- a process of rubbing, grinding, or pulverizing a powder to create fine particles Spatulation Mixing powders using a spatula in a mortar, an ointment slab, or a plastic bag; it is a process which ingredients may liquefy upon mixing; there is no reduction in particle size

31 Question 14 Which of the following ointment bases is anhydrous?
Oleaginous Water-oil emulsion base Oil-water base Water-miscible base

32 Question 14 Which of the following ointment bases is anhydrous?
Oleaginous Water-oil emulsion base Contains water Oil-water base Water-miscible base Miscible- forming a homogenous mixture when added together **Anhydrous = containing no water rich in, covered with, or producing oil; oily or greasy = oleaginous

33 Question 15 Which of the following is a disadvantage of liquid dosage forms? Easier to swallow than a solid dosage form for many patients Uniformity and flexibility of dosage form in dosing Effective more quickly than a solid dosage form because the drug is already dissolved May require preservatives to prevent bacteria or mold from developing

34 Question 15 Which of the following is a disadvantage of liquid dosage forms? Easier to swallow than a solid dosage form for many patients Uniformity and flexibility of dosage form in dosing Effective more quickly than a solid dosage form because the drug is already dissolved May require preservatives to prevent bacteria or mold from developing A liquid dosage form may require preservatives to prevent bacteria or mold from developing. All of the other choices are advantages of liquid dosage forms.

35 Question 16 Which of the following factors would least likely affect a medication that is in an amber-colored container? Humidity Light Temperature Dosage Form Amber vials protect the medication from light. The other factors would not necessarily be affected by the color of the container.

36 Question 16 Which of the following factors would least likely affect a medication that is in an amber-colored container? Humidity Light Temperature Dosage Form Amber vials protect the medication from light. The other factors would not necessarily be affected by the color of the container.

37 Question 17 Which of the following is not an advantage of a solid dosage form? Convenient for self-medication Takes a longer time for the medication to take effect Easy to package and dispense Lacks taste or smell Prepared quicker with heat

38 Question 17 Which of the following is not an advantage of a solid dosage form? Convenient for self-medication Takes a longer time for the medication to take effect Easy to package and dispense Lacks taste or smell Prepared quicker with heat

39 Question 18 Which dosage form is contained in a gelatin shell? Capsule
Effervescent salts Pastilles Suppositories Prepared quicker with heat

40 Question 18 Which dosage form is contained in a gelatin shell? Capsule
Effervescent salts Pastilles Suppositories Prepared quicker with heat

41 Question 19 How do ampules differ from vials?
Ampules can be used multiple times Ampules remain a close system upon breaking Ampules require the use of a filter needle Vials require the use of a filter needle Prepared quicker with heat

42 Question 19 How do ampules differ from vials?
Ampules can be used multiple times Ampules remain a close system upon breaking Ampules require the use of a filter needle Vials require the use of a filter needle Prepared quicker with heat

43 Question 20 Which of the following auxiliary labels should be affixed to a reconstituted medication? For ophthalmic use For otic use Refrigerate Shake Well Prepared quicker with heat

44 Question 20 Which of the following auxiliary labels should be affixed to a reconstituted medication? For ophthalmic use For otic use Refrigerate Shake Well Prepared quicker with heat


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