Zuoheng Wang, Mary Sara McPeek  The American Journal of Human Genetics 

Slides:



Advertisements
Similar presentations
Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants Martin F. Arlt, Jennifer G.
Advertisements

Nuclear and Mitochondrial DNA Analysis of a 2,000-Year-Old Necropolis in the Egyin Gol Valley of Mongolia Christine Keyser-Tracqui, Eric Crubézy, Bertrand.
Length Distributions of Identity by Descent Reveal Fine-Scale Demographic History Pier Francesco Palamara, Todd Lencz, Ariel Darvasi, Itsik Pe’er The American.
TFIIH Subunit Alterations Causing Xeroderma Pigmentosum and Trichothiodystrophy Specifically Disturb Several Steps during Transcription Amita Singh, Emanuel.
Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and.
The Novel Genetic Disorder Microhydranencephaly Maps to Chromosome 16p  
Connexin Mutations in Skin Disease and Hearing Loss David P. Kelsell, Wei-Li Di, Mark J. Houseman The American Journal of Human Genetics Volume 68, Issue.
Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation Amnon Koren, Paz Polak, James Nemesh, Jacob J. Michaelson,
Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease- Causing Point Mutations Renee P. Stokowski, David R. Cox The American.
Gene Preference in Maple Syrup Urine Disease Mary M. Nellis, Dean J. Danner The American Journal of Human Genetics Volume 68, Issue 1, Pages (January.
Alternative Splicing QTLs in European and African Populations Halit Ongen, Emmanouil T. Dermitzakis The American Journal of Human Genetics Volume 97, Issue.
A Multilocus Model of the Genetic Architecture of Autoimmune Thyroid Disorder, with Clinical Implications Veronica J. Vieland, Yungui Huang, Christopher.
Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part I: Methods and Power Analysis Douglas F. Levinson, Matthew D. Levinson, Ricardo Segurado,
Genomewide Comparison of DNA Sequences between Humans and Chimpanzees Ingo Ebersberger, Dirk Metzler, Carsten Schwarz, Svante Pääbo The American Journal.
Fragile X and X-Linked Intellectual Disability: Four Decades of Discovery Herbert A. Lubs, Roger E. Stevenson, Charles E. Schwartz The American Journal.
The Duty to Recontact: Attitudes of Genetics Service Providers Jennifer L. Fitzpatrick, Cecil Hahn, Teresa Costa, Marlene J. Huggins The American Journal.
PRIMUS: Rapid Reconstruction of Pedigrees from Genome-wide Estimates of Identity by Descent Jeffrey Staples, Dandi Qiao, Michael H. Cho, Edwin K. Silverman,
Peopling of Sahul: mtDNA Variation in Aboriginal Australian and Papua New Guinean Populations Alan J. Redd, Mark Stoneking The American Journal of Human.
The Trimmed-Haplotype Test for Linkage Disequilibrium
A Common Variant in SLC8A1 Is Associated with the Duration of the Electrocardiographic QT Interval  Jong Wook Kim, Kyung-Won Hong, Min Jin Go, Sung Soo.
Anna Middleton, J. Hewison, R.F. Mueller 
Transmission/Disequilibrium Tests for Extended Marker Haplotypes
Genetic Landscape of Eurasia and “Admixture” in Uyghurs
Public Opinion about the Importance of Privacy in Biobank Research
Anna Middleton, J. Hewison, R.F. Mueller 
Rapid Simulation of P Values for Product Methods and Multiple-Testing Adjustment in Association Studies  S.R. Seaman, B. Müller-Myhsok  The American Journal.
The Importance of Genealogy in Determining Genetic Associations with Complex Traits  Dina L. Newman, Mark Abney, Mary Sara McPeek, Carole Ober, Nancy J.
Common Variants of Large Effect in F12, KNG1, and HRG Are Associated with Activated Partial Thromboplastin Time  Lorna M. Houlihan, Gail Davies, Albert.
A Locus on Chromosome 1p36 Is Associated with Thyrotropin and Thyroid Function as Identified by Genome-wide Association Study  Vijay Panicker, Scott G.
2016 Curt Stern Award Address: From Rare to Common Diseases: Translating Genetic Discovery to Therapy1  Brendan Lee  The American Journal of Human Genetics 
Comparing Algorithms for Genotype Imputation
Meta-analysis of Genetic-Linkage Analysis of Quantitative-Trait Loci
Linkage Thresholds for Two-stage Genome Scans
Detecting and Estimating Contamination of Human DNA Samples in Sequencing and Array-Based Genotype Data  Goo Jun, Matthew Flickinger, Kurt N. Hetrick,
Estimating Kinship in Admixed Populations
Genetics, Individuality, and Medicine in the 21st Century*
The American Journal of Human Genetics 
Weight Loss after Gastric Bypass Is Associated with a Variant at 15q26
Kristina Allen-Brady, Peggy A. Norton, James M
Transethnic Genetic-Correlation Estimates from Summary Statistics
Sang Hong Lee, Naomi R. Wray, Michael E. Goddard, Peter M. Visscher 
A Weighted False Discovery Rate Control Procedure Reveals Alleles at FOXA2 that Influence Fasting Glucose Levels  Chao Xing, Jonathan C. Cohen, Eric Boerwinkle 
Value for Money? Array Genomic Hybridization for Diagnostic Testing for Genetic Causes of Intellectual Disability  Dean A. Regier, Jan M. Friedman, Carlo.
News & Notes Journal of Allergy and Clinical Immunology
Accurate Non-parametric Estimation of Recent Effective Population Size from Segments of Identity by Descent  Sharon R. Browning, Brian L. Browning  The.
Johanna Jakobsdottir, Mary Sara McPeek 
Dan-Yu Lin, Zheng-Zheng Tang  The American Journal of Human Genetics 
The SNP Endgame: A Multidisciplinary Approach*
Erratum The American Journal of Human Genetics
Template-Directed Dye-Terminator Incorporation with Fluorescence Polarization Detection for Analysis of Single Nucleotide Polymorphisms Implicated in.
On a Randomization Procedure in Linkage Analysis
Female-to-Male Breeding Ratio in Modern Humans—an Analysis Based on Historical Recombinations  Damian Labuda, Jean-François Lefebvre, Philippe Nadeau,
Long Homozygous Chromosomal Segments in Reference Families from the Centre d'Étude du Polymorphisme Humain  Karl W. Broman, James L. Weber  The American.
A Versatile Gene-Based Test for Genome-wide Association Studies
Greg L. Loeben, Theresa M. Marteau, Benjamin S. Wilfond 
Wei Pan, Il-Youp Kwak, Peng Wei  The American Journal of Human Genetics 
Victor Almon McKusick, MD, 1921–2008, In Memoriam
L-GATOR: Genetic Association Testing for a Longitudinally Measured Quantitative Trait in Samples with Related Individuals  Xiaowei Wu, Mary Sara McPeek 
Trevor J. Pemberton, Chaolong Wang, Jun Z. Li, Noah A. Rosenberg 
President's page: Presenting the 1993–1994 board of directors
Discussion The Journal of Thoracic and Cardiovascular Surgery
Jung-Ying Tzeng, Chih-Hao Wang, Jau-Tsuen Kao, Chuhsing Kate Hsiao 
Inclusion of Gene-Gene and Gene-Environment Interactions Unlikely to Dramatically Improve Risk Prediction for Complex Diseases  Hugues Aschard, Jinbo.
Common Variants of Large Effect in F12, KNG1, and HRG Are Associated with Activated Partial Thromboplastin Time  Lorna M. Houlihan, Gail Davies, Albert.
Anupama Srinivasan, Diana W. Bianchi, Hui Huang, Amy J
Harold A. Nieuwboer, René Pool, Conor V. Dolan, Dorret I
Alice S. Whittemore, Jerry Halpern 
Anna Middleton, J. Hewison, R.F. Mueller 
Hannah R. Elliott, David C. Samuels, James A. Eden, Caroline L
Sanjay Shete, Xiaojun Zhou, Christopher I. Amos 
Presentation transcript:

ATRIUM: Testing Untyped SNPs in Case-Control Association Studies with Related Individuals  Zuoheng Wang, Mary Sara McPeek  The American Journal of Human Genetics  Volume 85, Issue 5, Pages 667-678 (November 2009) DOI: 10.1016/j.ajhg.2009.10.006 Copyright © 2009 The American Society of Human Genetics Terms and Conditions

Figure 1 Association Results for Type 2 Diabetes in Framingham SHARe for the Region 10q25-q26 −log10(p value) is plotted against chromosomal location for 4,550 typed SNPs (blue circles) and 12,653 untyped SNPs (red x). The American Journal of Human Genetics 2009 85, 667-678DOI: (10.1016/j.ajhg.2009.10.006) Copyright © 2009 The American Society of Human Genetics Terms and Conditions

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2024 SlidePlayer.com Inc. All rights reserved.