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Dan-Yu Lin, Zheng-Zheng Tang  The American Journal of Human Genetics 

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Presentation on theme: "Dan-Yu Lin, Zheng-Zheng Tang  The American Journal of Human Genetics "— Presentation transcript:

1 A General Framework for Detecting Disease Associations with Rare Variants in Sequencing Studies 
Dan-Yu Lin, Zheng-Zheng Tang  The American Journal of Human Genetics  Volume 89, Issue 3, Pages (September 2011) DOI: /j.ajhg Copyright © 2011 The American Society of Human Genetics Terms and Conditions

2 Figure 1 Quantile-Quantile Plots of p Values on the –log10 Scale for the Asymptotic T1, T5, Fp, and VT Tests in the Quantitative Trait Analysis of Total Cholesterol The American Journal of Human Genetics  , DOI: ( /j.ajhg ) Copyright © 2011 The American Society of Human Genetics Terms and Conditions

3 Figure 2 Quantile-Quantile Plots of p Values on the –log10 Scale for the Permutation EREC, T5, Fp, and VT Tests in the Quantitative Trait Analysis of Total Cholesterol The American Journal of Human Genetics  , DOI: ( /j.ajhg ) Copyright © 2011 The American Society of Human Genetics Terms and Conditions

4 Figure 3 Quantile-Quantile Plots of p Values on the –log10 Scale for the Asymptotic T1, T5, Fp, and VT Tests in the Binary Trait Analysis of Total Cholesterol The American Journal of Human Genetics  , DOI: ( /j.ajhg ) Copyright © 2011 The American Society of Human Genetics Terms and Conditions

5 Figure 4 Quantile-Quantile Plots of p Values on the –log10 Scale for the Bootstrap EREC, T5, Fp, and VT Tests in the Binary Trait Analysis of Total Cholesterol The American Journal of Human Genetics  , DOI: ( /j.ajhg ) Copyright © 2011 The American Society of Human Genetics Terms and Conditions


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