The relative efficacy of topical non-steroidal anti-inflammatory drugs and capsaicin in osteoarthritis: a network meta-analysis of randomised controlled.

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Presentation transcript:

The relative efficacy of topical non-steroidal anti-inflammatory drugs and capsaicin in osteoarthritis: a network meta-analysis of randomised controlled trials M.S.M. Persson, J. Stocks, D.A. Walsh, M. Doherty, W. Zhang Osteoarthritis and Cartilage Volume 26, Issue 12, Pages 1575-1582 (December 2018) DOI: 10.1016/j.joca.2018.08.008 Copyright © 2018 The Author(s) Terms and Conditions

Fig. 1 PRISMA flow diagram. Results of the systematic literature search for placebo-controlled trials of topical NSAIDs and capsaicin in OA. Osteoarthritis and Cartilage 2018 26, 1575-1582DOI: (10.1016/j.joca.2018.08.008) Copyright © 2018 The Author(s) Terms and Conditions

Fig. 2 Risk of bias assessment. Risk of bias scores for all studies included in the overall analysis. Osteoarthritis and Cartilage 2018 26, 1575-1582DOI: (10.1016/j.joca.2018.08.008) Copyright © 2018 The Author(s) Terms and Conditions

Fig. 3 Trial network diagram. Nodes (circles) are weighted to represent the number of participants using each intervention. The solid lines represent the direct comparisons of the treatments in RCTs. The dotted line represents indirect comparisons generated through the NMA. The lines are weighted to represent the number of comparisons. Osteoarthritis and Cartilage 2018 26, 1575-1582DOI: (10.1016/j.joca.2018.08.008) Copyright © 2018 The Author(s) Terms and Conditions