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Non-steroidal anti-inflammatory drugs in the oncological surgical population: beneficial or harmful? A systematic review of the literature  J.P. Cata,

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Presentation on theme: "Non-steroidal anti-inflammatory drugs in the oncological surgical population: beneficial or harmful? A systematic review of the literature  J.P. Cata,"— Presentation transcript:

1 Non-steroidal anti-inflammatory drugs in the oncological surgical population: beneficial or harmful? A systematic review of the literature  J.P. Cata, C.E. Guerra, G.J. Chang, V. Gottumukkala, G.P. Joshi  British Journal of Anaesthesia  Volume 119, Issue 4, Pages (October 2017) DOI: /bja/aex225 Copyright © 2017 The Author(s) Terms and Conditions

2 Fig 1 The PRISMA flow diagram summarizes the literature search and selection process of relevant manuscripts on non-steroidal anti-inflammatory drugs (NSAIDs) and anastomotic leaks. British Journal of Anaesthesia  , DOI: ( /bja/aex225) Copyright © 2017 The Author(s) Terms and Conditions

3 Fig 2 The PRISMA flow diagram summarizes the literature search and selection process of relevant manuscripts on non-steroidal anti-inflammatory drugs (NSAIDs) and cancer recurrence. British Journal of Anaesthesia  , DOI: ( /bja/aex225) Copyright © 2017 The Author(s) Terms and Conditions

4 Fig 3 This figure depicts potential mechanisms behind NSAIDs-induced anastomotic leaks. NSAIDs, non-steroidal anti-inflammatory drugs; COX-2, cyclooxygenase-2 enzyme; (+), favouring healing effect; (-), inhibitory healing effect. British Journal of Anaesthesia  , DOI: ( /bja/aex225) Copyright © 2017 The Author(s) Terms and Conditions

5 Fig 4 This figure illustrates the postulated mechanisms by which non-steroidal anti-inflammatory drugs (NSAIDs) administered in the perioperative period may reduce cancer recurrence. British Journal of Anaesthesia  , DOI: ( /bja/aex225) Copyright © 2017 The Author(s) Terms and Conditions


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