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Symptomatic efficacy of avocado–soybean unsaponifiables (ASU) in osteoarthritis (OA) patients: a meta-analysis of randomized controlled trials  R. Christensen,

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Presentation on theme: "Symptomatic efficacy of avocado–soybean unsaponifiables (ASU) in osteoarthritis (OA) patients: a meta-analysis of randomized controlled trials  R. Christensen,"— Presentation transcript:

1 Symptomatic efficacy of avocado–soybean unsaponifiables (ASU) in osteoarthritis (OA) patients: a meta-analysis of randomized controlled trials  R. Christensen, M.Sc., E.M. Bartels, D.Sc., A. Astrup, M.D., Ph.D., H. Bliddal, M.D., Ph.D.  Osteoarthritis and Cartilage  Volume 16, Issue 4, Pages (April 2008) DOI: /j.joca Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Flow of RCTs included in the systematic review.
Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 Forest-plots of trials comparing ASU with placebo on pain, Lequesne, and the number of responders to treatment, respectively; size of every circle is proportional to the precision of each efficacy estimate. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

4 Fig. 3 Meta-regression relations: ESs (ESpain, ESLequesne, and ORresponders) on the vertical axis are plotted against the %hip OA patients included (A, C, and E) and trial duration (B, D, and F), respectively. Size of every circle is proportional to the precision of each efficacy estimate. The solid line indicates the predicted treatment magnitude and direction, whereas the dashed lines represent 95% CI using a REML based model. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

5 Osteoarthritis and Cartilage 2008 16, 399-408DOI: (10. 1016/j. joca
Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions


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