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A systematic review of the efficacy and general safety of antibodies to NGF in the treatment of OA of the hip or knee  T.J. Schnitzer, J.A. Marks  Osteoarthritis.

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Presentation on theme: "A systematic review of the efficacy and general safety of antibodies to NGF in the treatment of OA of the hip or knee  T.J. Schnitzer, J.A. Marks  Osteoarthritis."— Presentation transcript:

1 A systematic review of the efficacy and general safety of antibodies to NGF in the treatment of OA of the hip or knee  T.J. Schnitzer, J.A. Marks  Osteoarthritis and Cartilage  Volume 23, Pages S8-S17 (January 2015) DOI: /j.joca Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Phase II efficacy data; standard mean change [95% CI] in WOMAC pain compared to baseline by dosing group. Osteoarthritis and Cartilage  , S8-S17DOI: ( /j.joca ) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 Phase III efficacy data; standard mean change [95% CI] in WOMAC pain compared to baseline by dosing group. Osteoarthritis and Cartilage  , S8-S17DOI: ( /j.joca ) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

4 Fig. 3 Withdrawals due to AEs; odds ratio [95% CI] by treatment groups. Osteoarthritis and Cartilage  , S8-S17DOI: ( /j.joca ) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

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