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A. W. A. Baltzer, M. D. , C. Moser, M. D. , S. A. Jansen, M. D. , R

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Presentation on theme: "A. W. A. Baltzer, M. D. , C. Moser, M. D. , S. A. Jansen, M. D. , R"— Presentation transcript:

1 Autologous conditioned serum (Orthokine) is an effective treatment for knee osteoarthritis 
A.W.A. Baltzer, M.D., C. Moser, M.D., S.A. Jansen, M.D., R. Krauspe, M.D.  Osteoarthritis and Cartilage  Volume 17, Issue 2, Pages (February 2009) DOI: /j.joca Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Patient disposition. Flow chart showing screening and inclusion of patients. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 WOMAC scores (0–10 scale) as a function of time and treatment group 2 years after the last trial injections. (a) Valid-for-efficacy-population (N=188): patients who did not receive subsequent pharmacological or surgical treatment for OA (ACS: N=76; HA: N=56; saline: N=56). Figure shows mean±SE. *P<0.05 for the comparison ACS vs HA and saline; ‡P>0.05 for the comparison HA vs saline. (b) Intention-to-treat (LOCF) population (N=310): overall cohort with last value carried forward in patients who received subsequent therapies. Figure shows mean±SE. *P<0.05 for the comparison ACS vs HA and saline; ‡P>0.05 for the comparison HA vs saline. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2008 Osteoarthritis Research Society International Terms and Conditions


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