Nat. Rev. Cardiol. doi: /nrcardio

Slides:

Advertisements

Similar presentations

Left Ventricular Pressure-Volume Loops

Advertisements

Valve Defects /Cardiac Cycle

Ventricular Pressure loop

Paradoxical low flow and/or low gradient severe aortic stenosis despite preserved left ventricular ejection fraction: implications for diagnosis and treatment.

Left ventricle Michel Slama Amiens France. LV ventricle Ejection fraction Cardiac output Left ventricular filling pressure.

Events of the Cardiac Cycle Why did the blood flow across the valve? Desire - it wanted to Ability - it could do it Movement = Desire X Ability Flow.

Date of download: 6/29/2016 Copyright © The American College of Cardiology. All rights reserved. From: The Emerging Role of Exercise Testing and Stress.

Date of download: 7/7/2016 Copyright © The American College of Cardiology. All rights reserved. From: ACC/AHA guidelines for the management of patients.

Cardiac Function in Disease Robert A. Augustyniak, PhD

Pharmacotherapy Of Cardiovascular Disorders: Heart Failure

Management of mitral regurgitation. See legend for Fig

Figure 1 Initial management of a patient with acute heart failure

Nat. Rev. Cardiol. doi: /nrcardio

Heart - Pathophysiology

Normal physiology (control) is compared to that of acute mitral regurgitation (chordal rupture), compensated mitral regurgitation, and decompensated chronic.

Pathophysiology of valvular heart diseases

Echocardiographic modalities for evaluation and risk stratification of heart failure patients. 3D indicates 3-dimensional; EF, ejection fraction; LA, left.

Aortic valve replacement in low-flow, low-gradient aortic stenosis: Left ventricular ejection fraction matters Victor Dayan, MD, PhD, Philippe Pibarot,

Nat. Rev. Cardiol. doi: /nrcardio

Figure 10 Assessment of myocardial fibrosis

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Figure 3 Imaging characteristics of cardiac myxoma

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Figure 8 4D magnetic resonance imaging patterns

Figure 2 Echocardiographic methods to estimate left atrial pressure

Figure 4 Effects of delaying cardioprotective medications after anthracycline administration Figure 4 | Effects of delaying cardioprotective medications.

Figure 6 Speckle tracking echocardiography to

Figure 4 Doppler echocardiographic assessment

Figure 2 Results of diastolic stress testing

Ao, aorta; AR, aortic regurgitation; CFD, color-flow Doppler; LV, left ventricle; LV EDP, left ventricular end-diastolic pressure; PW, pulse-wave; SBP,

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Figure 3 A patient with aortic and mitral stenosis

Johannes Steiner et al. JACC 2017;70:

Johannes Steiner et al. JACC 2017;70:

Nat. Rev. Cardiol. doi: /nrcardio

ASSESSMENT OF MULTIVALVULAR LESION.

Figure 2 A patient with aortic stenosis and mitral regurgitation

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Figure 3 Challenges for big data applications in cardiovascular care

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Figure 3 Effects of cardiovascular medication on the fetus

Mitral Regurgitation in Ventricular Premature Contractions

Heart valve disease in general practice: a clinical overview

Figure 1 Ventricular end-diastolic pressure–volume relationship curves

Cardiac cycle DR S.PARTHASARATHY MD., DA., DNB., DIP. DIAB. PhD, FICA, IDRA, Diploma in software based statistics.

Figure 6 The haemodynamic effects of

Nat. Rev. Cardiol. doi: /nrcardio

Figure 2 Impaired mitochondrial capacity and function in heart failure

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Nat. Rev. Cardiol. doi: /nrcardio

Rick A. Nishimura et al. JACC 2014;63:e57-e185

Patrick O’Gara et al. JIMG 2008;1:

Nat. Rev. Cardiol. doi: /nrcardio

Rick A. Nishimura et al. JACC 2017;70:

Introduction; The Cardiovascular System (CVS)

Patient selection process in the present study.

David H. Harpole, MD, Stanley A. Gall, MD, Walter G. Wolfe, MD, J

Presentation transcript:

Nat. Rev. Cardiol. doi:10.1038/nrcardio.2016.57 Figure 1 Pathophysiology of combined aortic stenosis and mitral regurgitation Figure 1 | Pathophysiology of combined aortic stenosis and mitral regurgitation. Mitral valve deformation and tethering, as well as an increase in transmitral pressure gradient caused by aortic stenosis, all contribute to mitral regurgitation. Increased left ventricular (LV) afterload related to aortic stenosis, combined with mitral regurgitation, result in a decrease in forward LV stroke volume and, therefore, often to a low-flow, low-gradient pattern. Both aortic stenosis and mitral regurgitation can, in the long-term, induce LV myocardial fibrosis and dysfunction. However, the extent of LV systolic dysfunction in such cases is underestimated by LV ejection fraction owing to the LV concentric remodelling related to aortic stenosis and the retrograde flow (mitral regurgitant volume) related to mitral regurgitation. Unger, P. et al. (2016) Pathophysiology and management of multivalvular disease Nat. Rev. Cardiol. doi:10.1038/nrcardio.2016.57