Management of hypertension in patients with chronic kidney disease Matthew Weir  Journal of Indian College of Cardiology  Volume 5, Pages S43-S48 (March 2015) DOI: 10.1016/j.jicc.2015.03.019 Copyright © 2015 Terms and Conditions

Fig. 1 The glomerular apparatus of the kidney. Journal of Indian College of Cardiology 2015 5, S43-S48DOI: (10.1016/j.jicc.2015.03.019) Copyright © 2015 Terms and Conditions

Fig. 2 Relationship of renal damage to blood pressure. Journal of Indian College of Cardiology 2015 5, S43-S48DOI: (10.1016/j.jicc.2015.03.019) Copyright © 2015 Terms and Conditions

Fig. 3 Estimated mean decline in glomerular filtration rate (GFR) from baseline to selected follow-up times in MDRD (Continuous line: BP125/75, dashed line: BP 140/90). Source: Peterson JC, et al. Annals of Internal Medicine 1995;123: 754–762 Journal of Indian College of Cardiology 2015 5, S43-S48DOI: (10.1016/j.jicc.2015.03.019) Copyright © 2015 Terms and Conditions

Fig. 4 Proportion of patients with end-stage renal disease in each study arm. Source: Ruggenenti, P. et. Al, Lancet 2005; 365–939–46 Journal of Indian College of Cardiology 2015 5, S43-S48DOI: (10.1016/j.jicc.2015.03.019) Copyright © 2015 Terms and Conditions

Fig. 5 Cumulative incidence of the composite primary outcome, According to baseline proteinuria status. Source: Appel LJ et al. N Engl J Med 2010; 363:918–929 Journal of Indian College of Cardiology 2015 5, S43-S48DOI: (10.1016/j.jicc.2015.03.019) Copyright © 2015 Terms and Conditions

Fig. 6 Relative risk for kidney disease progression (based on current level of systolic blood pressure and current urine protein excretion). Source: Jafar TH, et al. Ann Intern Med 2003; 139: 244–252 Journal of Indian College of Cardiology 2015 5, S43-S48DOI: (10.1016/j.jicc.2015.03.019) Copyright © 2015 Terms and Conditions

Fig. 7 Impact of quartile of achieved mean systolic blood pressure on time to renal endpoint. Source: Pohl MA, et. al. J Am Soc Nephrol 2005; 16: 3027–3037 Journal of Indian College of Cardiology 2015 5, S43-S48DOI: (10.1016/j.jicc.2015.03.019) Copyright © 2015 Terms and Conditions

Fig. 8 Natural log of the relative risk for reaching a renal endpoint by level of achieved follow-up SBP. Source: Pohl MA, et. al. J Am Soc Nephrol 2005; 16: 3027–3037 Journal of Indian College of Cardiology 2015 5, S43-S48DOI: (10.1016/j.jicc.2015.03.019) Copyright © 2015 Terms and Conditions

Fig. 9 Differences in endpoint outcomes in two groups of REIN-2 trial. Source: Ruggenenti P et al Lancet. 2005; 365: 939–946 Journal of Indian College of Cardiology 2015 5, S43-S48DOI: (10.1016/j.jicc.2015.03.019) Copyright © 2015 Terms and Conditions

Fig. 10 CV event rates and mortality in AASK. Source: Wright, JT Jr, JAMA. 2002; 288: 2421–2431 Journal of Indian College of Cardiology 2015 5, S43-S48DOI: (10.1016/j.jicc.2015.03.019) Copyright © 2015 Terms and Conditions

Fig. 11 Hazard ratio for cardiovascular and heart failure end points as functions of percent change in month-6 albuminuria. Source: De Zeeuw et al; Circulation. 2004;110:921–927 Journal of Indian College of Cardiology 2015 5, S43-S48DOI: (10.1016/j.jicc.2015.03.019) Copyright © 2015 Terms and Conditions