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From secondary to primary prevention of progressive renal disease: The case for screening for albuminuria Paul E. De Jong, Barry M. Brenner Kidney International Volume 66, Issue 6, Pages (December 2004) DOI: /j x Copyright © 2004 International Society of Nephrology Terms and Conditions
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Figure 1 The longitudinal data on glomerular filtration rate (GFR) and urinary albumin excretion in type 1 diabetes, showing that initially hyperfiltration is present. Next, in time, albumin excretion starts to rise. At that time, GFR starts to drop, to ultimately reach the level of end-stage renal failure and macroproteinuria (derived from32). The stippled area in the GFR plot indicates the normal value; the hatched area in the albuminuria plot refers to the microalbuminuria range. Kidney International , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions
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