Non-sterile compounding

Slides:



Advertisements
Similar presentations
Drug Forms and Routes of Administration. Before FDA approval Rx company must clearly state in what form or forms the drug will be manufactured Rx company.
Advertisements

Solutions.
Extemporaneous Compounding
Nonsterile Pharmaceutical Compounding
PREPARATION.
CREAMS MS.WAJIHA IFFAT OBJECTIVES: After the end of this topic, the student will be able to : Define creams Classify creams Method of preparation prepare.
Chocolate Ganache.
DRUG DOSAGE FORMS Dr.Abdul Latif Mahesar.
MIXTURES.
dispersed system Liquid preparations containing undissolved or immiscible drug distributed throughout a vehicle. In these preparations, the substance.
PRINCIPLES OF COMPOUNDING Terrick Andey College of Pharmacy & Pharmaceutical Sciences Florida A&M University February 2013.
Semisolid Dosage Forms
Unit 3 Solutions Chemistry
Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved. The Pharmacy Technician: Foundations and Practices.
COS 2.0, 2.1, 2.2, 2.3 IDENTIFY SOLUTIONS IN TERMS OF COMPONENTS, SOLUBILITY, CONCENTRATION, AND CONDUCTIVITY. COMPARE SATURATED, UNSATURATED AND SUPERSATURATD.
Preparation in Pharmacy of Hospital
Desiccation ,sublimation & tirturation
When a substance dissolves, it goes into solution. A solution is a mixture in which the particles of one substance are evenly mixed with the particles.
Chapter 6 Solutions, Acids, and Bases
Properties of Matter Chapter 2 & 8. “Properties of Matter” Matter is anything that has mass and occupies space. –Matter is made of atoms which are the.
COMPOUNDING CHAPTER 8.
Kh. Sadique Faisal Asst. Lecturer Northern University Bangladesh
Weighing Dr. Amani M. Elsayed. Learning Objectives Upon completion of this exercise, you should be able to: Define percentage error and state the percentage.
1 Suspension 1. 2  Suspension:  Suspension: A suspension is a two-phase system consisting of a finely divided solid particles dispersed in liquid, or.
Formulation of suspensions Flocculating agents Suspending/ thicking agents Wetting agents Dispersing agents Preservatives Organoleptic additives.
 Trituration – reducing substances to fine particles by rubbing or grinding them with a mortar and pestle or on an ointment slab.  Geometric dilution.
1.  Chapter 8 covers pages  Objective  Explain need for compounding  Know equipment needed for compounding  Know techniques for compounding.
Notes:Color Guide Gold : Important concept. Write this down. Orange : Definition. Write this down. Blue : Important information, but you do not need to.
PREPARATION OF OINTMENTS. Selection of The Appropriate Base Selection of the base to use in the formulation of an ointment depends on careful assessment.
Non Sterile Pharmaceutical Compounding. Chapter Topics Sterile and nonsterile compounding Laws, regulations, and standards Regulations of pharmacy personnel.
Compounding. COMPOUNDINGCOMPOUNDING Compounding: the preparation, mixing, assembling and packaging or labeling of a drug or device. Extemporaneous Compounding:
POWDERS. Powders as a Dosage Form Powders are prepared either as dusting powders which are applied locally, dentifrices, products for reconstitution,
Chapter 15: Nonsterile Compounding and Repackaging
Chapter 7.  A heterogeneous mixture is a nonuniform blend of 2 or more substances  Examples of heterogeneous mixtures:  fruit salad  salsa  granite.
Compounding Chapter 9.
{ Medical Review Doses and Terminology Part 2.  Solid dosage forms which have been crushed to make a fine powder  Can be used internally or externally.
Solutions Formed when substances dissolve in other substances
Dispersed Systems. Dispersed system:  It is liquid preparations containing undissolved or immiscible drug distributed throughout a vehicle.  The substance.
Extemporaneous Compounding The process by which solutions, suspensions, ointments, creams, powders, suppositories, and capsules are prepared.
Unit 3 Solutions Chemistry
A Pharmaceutical powder is a mixture of finely divided drugs or chemicals in a dry form that may be intended for internal (oral powders) or external (topical.
Pharmacy Technician Compounding.
Ointments, Creams, Pastes, and Gels
Drug Forms and Routes of Administration
Solutions, Suspensions, and Emulsions
Solid dosage forms Tablets
Capsules, Tablets, and Powders
PHARMACY TECHNICIAN CHAPTER TEN.
Practicum in Pharmacy Technician
Unit 3 Solutions Chemistry
Unit 3 Solutions Chemistry
Non-Sterile Compounding
Mr. Kinton Honors Chemistry
Mr. Kinton Honors Chemistry
Types of Mixtures.
Lab -7- Capsules.
PREPARATION OF OINTMENTS
With your neighbor… Explain why saltwater is a mixture and NOT a compound. Hint: Look back at your notes from the PowerPoint.
Lab 3 Industrial pharmacy
Mixing and Homogenization Lab (1) Shahen S. Mohammed MSc pharmaceutics
Selected Calculations in Contemporary Compounding
Lab -7- Capsules.
Pharmaceutical Technology
POWDER AND GRANULES FADHILAH FAIROZA FATIN HUSNA
Unit 3 Solutions Chemistry
Aromatic Water By Assistant lect. Nora Zawar
Key Ideas What is a heterogeneous mixture?
Aromatic Water By Assistant lect. Nora Zawar
Unit 3 Solutions Chemistry
External Preparations Ointment
Presentation transcript:

Non-sterile compounding PTCE Practice Questions

Question 1 Which of the following establishes standards of quality, strength, purity, packaging, and labeling for compounded medications? USP-NF FDA ASHP DEA

Question 1 Which of the following establishes standards of quality, strength, purity, packaging, and labeling for compounded medications? USP-NF FDA ASHP DEA

Question 2 The storage temperature definition for a freezer is -30°C to 0°C -20°C to -10°C 8°C to 15°C 30°C to 40°C

Question 2 The storage temperature definition for a freezer is 2°C to 8°C- Cold -20°C to -10°C - Freezer 8°C to 15°C - Cool 30°C to 40°C - Warm

Question 3 The minimum weighable quantity for a class III balance is 120 mg 500 mL 120 mL 500 mg

Question 3 The minimum weighable quantity for a class III balance is 120 mg 500 mL 120 mL 500 mg Check your units! You can immediately get rid of “ml” answers!

Question 4 Metric weights used for weighing ingredients using a class III balance should be handled with Water Fingers Forceps oil

Question 4 Metric weights used for weighing ingredients using a class III balance should be handled with Water Fingers Forceps oil

Question 5 Quantities less than 120 mg may be measured using a/an Arrest Aliquot Calibration Sensitivity

Question 5 Quantities less than 120 mg may be measured using a/an Arrest Aliquot Calibration Sensitivity Aliquot- a portion of the whole

Question 6 ______________ is the term for triturating a powdered drug with a solvent in which it is insoluble to reduce it’s particle size Suspension Trituration Emulsion Levigation

Question 6 ______________ is the term for triturating a powdered drug with a solvent in which it is insoluble to reduce it’s particle size Suspension A 2 phase system with uniform dispersion of finely divided solid drug particles in a continuous phase of solid, liquid, or gas in which the drug has minimum solubility. Trituration Using a mortar and pestle to grind a drug solid to reduce particle size, or to mix two or more solids together Emulsion Mixture of 2 or more liquids that are normally immiscible Levigation The trituration of a powdered drug with a solvent in which the drug is insoluble to reduce the particle size of the drug

Question 7 The appropriate flavoring for a metallic tasting drug is Mint Orange Cinnamon Anise

Question 7 The appropriate flavoring for a metallic tasting drug is Mint Orange Cinnamon Anise

Question 7 Taste Flavor Salty Cinnamon, Raspeberry, Orange, Butterscotch Sweet Fruit, berry, vanilla Bitter Cocoa, chocolate, mint, cherry, walnut Sour/Acid Fruit, citrus, cherry Oily Wintergreen, peppermint, lemon, anise Metallic Mint, Marshallow

Question 8 A two-phase system consisting of a finely divided solid dispersed in a liquid is a/an Suspension Emulsion Solution Trituration

Question 8 A two-phase system consisting of a finely divided solid dispersed in a liquid is a/an Suspension Formulation in which the drug does not completely dissolve in the liquid Emulsion Mixture of 2 liquids that do not mix with eat other; one liquid is dispersed through the other by mixing and using an emulsifier for stability. Solution A clear liquid made up of one or more substances dissolved in a solvent Trituration The process of grinding powders to reduce particle size

Question 9 ____________ are thickening agents used in the preparation of suspensions Electrolytes Preservatives Flocculating agents Suspending agents

Question 9 ____________ are thickening agents used in the preparation of suspensions Electrolytes Substances that in solution form ions that conduct an electrical current Preservatives A substance used to preserve materials against decay Flocculating agents Electrolytes used in the prepartion of suspensions to form particles that can be easily redispersed Suspending agents A substance added to promote particle suspension or dispersion

Question 10 The punch method is used to prepare Tablets Capsules Suppositories Emulsions

Question 10 The punch method is used to prepare Tablets Capsules Suppositories Emulsions

Question 11 Which of the following is not a characteristic of an absorption base? Anhydrous Difficult to spread Nongreasy Nonwashable

Question 11 Which of the following is not a characteristic of an absorption base? Anhydrous Difficult to spread Nongreasy Nonwashable Which of these things is not like the other? (of a substance, especially a crystalline compound) containing no water- anhydrous

Question 12 If a pharmacy technician is using the continental (dry gum) method, what would he or she be compounding? Capsules Emulsions Suppositories Syrups

Question 12 If a pharmacy technician is using the continental (dry gum) method, what would he or she be compounding? Capsules Emulsions Suppositories Syrups An emulsion is a mixture of two or more liquids that are normally immiscible (unmixable or unblendable). May be compounded by dry gum, wet gum, or emulsion method

Question 13 What technique is used in mixing two ingredients of unequal quantities? Blending Geometric dilution Levigation Spatulation

Question 13 What technique is used in mixing two ingredients of unequal quantities? Blending An act of combining two substances Geometric dilution Levigation Trituration of a powder drug with a solvent in which the drug is insoluble with the solvent Trituration- a process of rubbing, grinding, or pulverizing a powder to create fine particles Spatulation Mixing powders using a spatula in a mortar, an ointment slab, or a plastic bag; it is a process which ingredients may liquefy upon mixing; there is no reduction in particle size

Question 14 Which of the following ointment bases is anhydrous? Oleaginous Water-oil emulsion base Oil-water base Water-miscible base

Question 14 Which of the following ointment bases is anhydrous? Oleaginous Water-oil emulsion base Contains water Oil-water base Water-miscible base Miscible- forming a homogenous mixture when added together **Anhydrous = containing no water rich in, covered with, or producing oil; oily or greasy = oleaginous

Question 15 Which of the following is a disadvantage of liquid dosage forms? Easier to swallow than a solid dosage form for many patients Uniformity and flexibility of dosage form in dosing Effective more quickly than a solid dosage form because the drug is already dissolved May require preservatives to prevent bacteria or mold from developing

Question 15 Which of the following is a disadvantage of liquid dosage forms? Easier to swallow than a solid dosage form for many patients Uniformity and flexibility of dosage form in dosing Effective more quickly than a solid dosage form because the drug is already dissolved May require preservatives to prevent bacteria or mold from developing A liquid dosage form may require preservatives to prevent bacteria or mold from developing. All of the other choices are advantages of liquid dosage forms.

Question 16 Which of the following factors would least likely affect a medication that is in an amber-colored container? Humidity Light Temperature Dosage Form Amber vials protect the medication from light. The other factors would not necessarily be affected by the color of the container.

Question 16 Which of the following factors would least likely affect a medication that is in an amber-colored container? Humidity Light Temperature Dosage Form Amber vials protect the medication from light. The other factors would not necessarily be affected by the color of the container.

Question 17 Which of the following is not an advantage of a solid dosage form? Convenient for self-medication Takes a longer time for the medication to take effect Easy to package and dispense Lacks taste or smell Prepared quicker with heat

Question 17 Which of the following is not an advantage of a solid dosage form? Convenient for self-medication Takes a longer time for the medication to take effect Easy to package and dispense Lacks taste or smell Prepared quicker with heat

Question 18 Which dosage form is contained in a gelatin shell? Capsule Effervescent salts Pastilles Suppositories Prepared quicker with heat

Question 18 Which dosage form is contained in a gelatin shell? Capsule Effervescent salts Pastilles Suppositories Prepared quicker with heat

Question 19 How do ampules differ from vials? Ampules can be used multiple times Ampules remain a close system upon breaking Ampules require the use of a filter needle Vials require the use of a filter needle Prepared quicker with heat

Question 19 How do ampules differ from vials? Ampules can be used multiple times Ampules remain a close system upon breaking Ampules require the use of a filter needle Vials require the use of a filter needle Prepared quicker with heat

Question 20 Which of the following auxiliary labels should be affixed to a reconstituted medication? For ophthalmic use For otic use Refrigerate Shake Well Prepared quicker with heat

Question 20 Which of the following auxiliary labels should be affixed to a reconstituted medication? For ophthalmic use For otic use Refrigerate Shake Well Prepared quicker with heat