Date of download: 5/28/2016 From: Association Between Exposure to Low to Moderate Arsenic Levels and Incident Cardiovascular Disease: A Prospective Cohort.

Slides:



Advertisements
Similar presentations
Date of download: 5/28/2016 From: New Fibrate Use and Acute Renal Outcomes in Elderly Adults: A Population-Based Study Ann Intern Med. 2012;156(8):
Advertisements

Date of download: 5/28/2016 From: Effect of the Medicare Part D Coverage Gap on Medication Use Among Patients With Hypertension and Hyperlipidemia Ann.
Date of download: 5/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Serum Selenium Levels and All-Cause, Cancer, and.
Date of download: 5/29/2016 From: Systematic Review: Comparative Effectiveness and Safety of Premixed Insulin Analogues in Type 2 Diabetes Ann Intern Med.
Date of download: 5/29/2016 From: The Effect of a Lower Target Blood Pressure on the Progression of Kidney Disease: Long-Term Follow- up of the Modification.
Date of download: 5/31/2016 From: Metabolic Risk Factors Worsen Continuously across the Spectrum of Nondiabetic Glucose Tolerance: The Framingham Offspring.
Date of download: 5/31/2016 From: Benefits, Harms, and Cost-Effectiveness of Supplemental Ultrasonography Screening for Women With Dense Breasts Ann Intern.
Date of download: 6/2/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Varespladib and Cardiovascular Events in Patients.
Date of download: 6/2/2016 From: Are Metabolically Healthy Overweight and Obesity Benign Conditions?: A Systematic Review and Meta- analysis Ann Intern.
Date of download: 6/2/2016 From: Internet-Based Self-management Plus Education Compared With Usual Care in Asthma: A Randomized Trial Ann Intern Med. 2009;151(2):
Date of download: 6/3/2016 From: Mortality Rates in Elderly Patients Who Take Different Angiotensin-Converting Enzyme Inhibitors after Acute Myocardial.
Date of download: 6/3/2016 From: Chest Pain Relief by Nitroglycerin Does Not Predict Active Coronary Artery Disease Ann Intern Med. 2003;139(12):
Date of download: 6/3/2016 From: Sex, Age, and Birth Cohort Effects in Colorectal Neoplasms: A Cohort Analysis Ann Intern Med. 2010;152(11): doi: /
Date of download: 6/3/2016 From: Surgery Versus Nonsurgical Treatment of Lumbar Spinal Stenosis: A Randomized Trial Ann Intern Med. 2015;162(7):
Date of download: 6/3/2016 From: Elevated Plasma Homocysteine Level Is an Independent Predictor of Coronary Heart Disease Events in Patients with Type.
Date of download: 6/3/2016 Copyright © The American College of Cardiology. All rights reserved. From: Effects of Habitual Coffee Consumption on Cardiometabolic.
Date of download: 6/3/2016 From: Increased Incidence of Aortic Aneurysm and Dissection in Giant Cell (Temporal) Arteritis: A Population- Based Study Ann.
Date of download: 6/18/2016 From: Treatment of Anemia in Patients With Heart Disease: A Systematic Review Ann Intern Med. 2013;159(11): doi: /
Date of download: 6/21/2016 From: The Epidemiology of Prescriptions Abandoned at the Pharmacy Ann Intern Med. 2010;153(10): doi: /
Date of download: 6/21/2016 From: HIV, Age, and the Severity of Hepatitis C Virus–Related Liver Disease: A Cohort Study Ann Intern Med. 2013;158(9):
Date of download: 6/21/2016 From: Aspirin, Statins, or Both Drugs for the Primary Prevention of Coronary Heart Disease Events in Men: A Cost–Utility Analysis.
Date of download: 6/22/2016 From: Biomarkers of Inflammation and Thrombosis as Predictors of Near-Term Mortality in Patients with Peripheral Arterial Disease:
Date of download: 6/23/2016 From: Relative Effectiveness of Osteoporosis Drugs for Preventing Nonvertebral Fracture Ann Intern Med. 2008;148(9):
Date of download: 6/23/2016 From: The Anticipated Clinical and Economic Effects of 90–90–90 in South Africa Ann Intern Med. Published online May 31, 2016.
Date of download: 6/25/2016 From: Interferon Therapy Reduces the Risk for Hepatocellular Carcinoma: National Surveillance Program of Cirrhotic and Noncirrhotic.
Date of download: 6/25/2016 From: Blood Pressure and Mortality in U.S. Veterans With Chronic Kidney Disease: A Cohort Study Ann Intern Med. 2013;159(4):
Date of download: 6/26/2016 From: Comparative Effectiveness and Safety of Methods of Insulin Delivery and Glucose Monitoring for Diabetes Mellitus: A Systematic.
Date of download: 6/26/2016 From: Comparative Effectiveness of Cardiac Resynchronization Therapy With an Implantable Cardioverter- Defibrillator Versus.
Date of download: 6/26/2016 From: Cost-Effectiveness of Adding Cardiac Resynchronization Therapy to an Implantable Cardioverter- Defibrillator Among Patients.
Date of download: 6/26/2016 From: Variation in Outpatient Antibiotic Prescribing for Acute Respiratory Infections in the Veteran Population: A Cross-sectional.
Date of download: 6/27/2016 From: Should Colorectal Cancer Screening Be Considered in Elderly Persons Without Previous Screening?: A Cost-Effectiveness.
Date of download: 6/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Urinary Sodium and Potassium Excretion and Risk of.
Date of download: 6/29/2016 From: Predicting Future Functional Status for Seriously Ill Hospitalized Adults: The SUPPORT Prognostic Model Ann Intern Med.
Date of download: 7/1/2016 From: Time-Updated Systolic Blood Pressure and the Progression of Chronic Kidney Disease: A Cohort Study Ann Intern Med. 2015;162(4):
Date of download: 7/2/2016 From: An Acute Change in Lung Allocation Score and Survival After Lung Transplantation: A Cohort Study Ann Intern Med. 2013;158(9):
Date of download: 7/3/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Fibroblast Growth Factor 23 and Risks of Mortality.
Date of download: 7/6/2016 From: Can Inexpensive Signs Encourage the Use of Stairs? Results from a Community Intervention Ann Intern Med. 1998;129(5):
Date of download: 7/8/2016 From: Economic Outcomes With Anatomical Versus Functional Diagnostic Testing for Coronary Artery Disease Ann Intern Med. Published.
Date of download: 7/8/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Troponin Criteria for Myocardial Infarction After.
Date of download: 7/9/2016 Copyright © 2016 American Medical Association. All rights reserved. From: A Prospective Study of Weight Training and Risk of.
Date of download: 9/17/2016 From: Behavioral Therapy to Enable Women with Urge Incontinence to Discontinue Drug Treatment: A Randomized Trial Ann Intern.
Date of download: 9/17/2016 Copyright © 2016 American Medical Association. All rights reserved. From: The Relationship Between Magnitude of Proteinuria.
Date of download: 9/17/2016 From: Topical Treatment of Pressure Ulcers with Nerve Growth Factor: A Randomized Clinical Trial Ann Intern Med. 2003;139(8):
Date of download: 9/18/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Effect of Structured Physical Activity on Prevention.
Date of download: 9/18/2016 From: “Nonfunctional” Adrenal Tumors and the Risk for Incident Diabetes and Cardiovascular Outcomes: A Cohort Study Ann Intern.
Date of download: 9/19/2016 From: The Implications of Regional Variations in Medicare Spending. Part 2: Health Outcomes and Satisfaction with Care Ann.
Date of download: 9/19/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Glycated Hemoglobin Measurement and Prediction of.
Date of download: 9/19/2016 From: Proton-Pump Inhibitors Are Associated With Increased Cardiovascular Risk Independent of Clopidogrel Use: A Nationwide.
Date of download: 9/20/2016 From: Breast Cancer in Black Women Ann Intern Med. 1996;124(10): doi: / Age-specific.
From: Visit-to-Visit Variability of Blood Pressure and Coronary Heart Disease, Stroke, Heart Failure, and Mortality: A Cohort Study Ann Intern Med. 2015;163(5):
Ann Intern Med. 2010;153(7): doi: / Figure Legend:
Ann Intern Med. 2016;165(7): doi: /M Figure Legend:
The SPRINT Research Group
Copyright © 2011 American Medical Association. All rights reserved.
From: Perioperative Use of Dobutamine in Cardiac Surgery and Adverse Cardiac Outcome:Propensity-adjusted Analyses Anesthes. 2008;108(6): doi: /ALN.0b013e f.
Ann Intern Med. 2016;164(8): doi: /M Figure Legend:
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies  The Emerging.
Ann Intern Med. 2000;133(6): doi: / Figure Legend:
Copyright © 2011 American Medical Association. All rights reserved.
Copyright © 2008 American Medical Association. All rights reserved.
From: Opioid Prescribing After Nonfatal Overdose and Association With Repeated OverdoseA Cohort Study Ann Intern Med. 2016;164(1):1-9. doi: /M
From: The Evolving Diabetes Burden in the United States
Copyright © 2004 American Medical Association. All rights reserved.
Ann Intern Med. 2009;150(11): doi: / Figure Legend:
Copyright © 2007 American Medical Association. All rights reserved.
From: Exercise Tomographic Thallium-201 Imaging in Patients with Severe Coronary Artery Disease and Normal Electrocardiograms Ann Intern Med. 1994;121(11):
From: Low-Molecular-Weight Heparins Compared with Unfractionated Heparin for Treatment of Acute Deep Venous Thrombosis: A Cost-Effectiveness Analysis Ann.
From: Using Standardized Serum Creatinine Values in the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate.
High Dietary Glycemic Load Increases the Risk of Non–Gallstone-Related Acute Pancreatitis: A Prospective Cohort Study  Viktor Oskarsson, Omid Sadr–Azodi,
Volume 86, Issue 3, Pages (September 2014)
Presentation transcript:

Date of download: 5/28/2016 From: Association Between Exposure to Low to Moderate Arsenic Levels and Incident Cardiovascular Disease: A Prospective Cohort Study Ann Intern Med. Published online September 24, doi: / Strong Heart Study clinic visits, follow-up, and data used in the present study. * Urinary arsenic concentrations were only available for 380 participants. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Date of download: 5/28/2016 From: Association Between Exposure to Low to Moderate Arsenic Levels and Incident Cardiovascular Disease: A Prospective Cohort Study Ann Intern Med. Published online September 24, doi: / Hazard ratios for cardiovascular disease and coronary heart disease incidence and mortality, by urinary arsenic concentration (n= 3575). Solid lines represent adjusted hazard ratios based on restricted quadratic splines for the log-transformed sum of inorganic and methylated arsenic species, with knots at the 10th, 50th, and 90th percentiles (3.8, 9.7, and 24.0 µg/g creatinine, respectively). The dotted lines represent upper and lower 95% CIs. The reference was set at the 10th percentile of the arsenic distribution (3.8 µg/g creatinine). Adjustment factors were the same as those for model 2 in Tables 1 and 2. The bars represent a histogram of urinary arsenic distribution among participants (the extreme tails of the histogram were truncated because only 1 participant had a urinary arsenic level 54.6 µg/g creatinine). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Date of download: 5/28/2016 From: Association Between Exposure to Low to Moderate Arsenic Levels and Incident Cardiovascular Disease: A Prospective Cohort Study Ann Intern Med. Published online September 24, doi: / Hazard ratios for stroke incidence, by urinary arsenic concentration (n= 3575). The solid line represents the adjusted hazard ratio based on restricted quadratic splines for the log-transformed sum of inorganic and methylated arsenic species, with knots at the 10th, 50th, and 90th percentiles (3.8, 9.7, and 24.0 µg/g creatinine, respectively). The dotted lines represent upper and lower 95% CIs. The reference was set at the 10th percentile of the arsenic distribution (3.8 µg/g creatinine). Adjustment factors were the same as those for model 2 in Tables 1 and 2. The bars represent a histogram of urinary arsenic distribution among participants (the extreme tails of the histogram were truncated because only 1 participant had a urinary arsenic level 54.6 µg/g creatinine). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Date of download: 5/28/2016 From: Association Between Exposure to Low to Moderate Arsenic Levels and Incident Cardiovascular Disease: A Prospective Cohort Study Ann Intern Med. Published online September 24, doi: / Hazard ratios and 95% CIs for cardiovascular disease and coronary heart disease mortality when an interquartile range of urinary arsenic concentrations is compared, by participant characteristics at baseline (n= 3575). Hazard ratios for cardiovascular disease and coronary heart disease mortality were stratified by each subgroup of interest, and associated P values for interaction were obtained from stratified Cox proportional hazards models with log-transformed arsenic (sum of inorganic and methylated arsenic species) as a continuous variable, adjusted for the same covariates as those in model 2 in 1 and 2. The interquartile range of urinary arsenic concentrations was 5.8 to 15.7 µg/g creatinine. For cardiovascular disease and coronary heart disease mortality hazard ratios by methylation indices (below and above the median proportions of inorganic arsenic, MMA, and DMA), the data set was restricted to participants with detectable inorganic arsenic, MMA, and DMA concentrations (n = 3381). For this subset, the corresponding urinary arsenic interquartile range was 6.1 to 16.2 µg/g creatinine. DMA = dimethylarsinate; HR = hazard ratio; MMA = monomethylarsonate. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Date of download: 5/28/2016 From: Association Between Exposure to Low to Moderate Arsenic Levels and Incident Cardiovascular Disease: A Prospective Cohort Study Ann Intern Med. Published online September 24, doi: / Hazard ratios and 95% CIs for cardiovascular disease incidence when an interquartile range of urinary arsenic concentrations is compared, by participant characteristics at baseline (n= 3575). Hazard ratios for cardiovascular disease incidence (fatal and nonfatal events) were stratified by each subgroup of interest, and associated P values for interaction were obtained from stratified Cox proportional hazards models with log-transformed arsenic (sum of inorganic and methylated arsenic species) as a continuous variable, adjusted for the same covariates as those in model 2 in the main analysis. The interquartile range of urinary arsenic concentrations was 5.8 to 15.7 µg/g creatinine. For cardiovascular disease incidence hazard ratios by methylation indices (below and above median proportions of inorganic arsenic, MMA, and DMA), the data set was restricted to participants with detectable inorganic arsenic, MMA, and DMA concentrations (n = 3381). For this subset, the corresponding urinary arsenic interquartile range was 6.1 to 16.2 µg/g creatinine. DMA = dimethylarsinate; HR = hazard ratio; MMA = monomethylarsonate. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Date of download: 5/28/2016 From: Association Between Exposure to Low to Moderate Arsenic Levels and Incident Cardiovascular Disease: A Prospective Cohort Study Ann Intern Med. Published online September 24, doi: / Hazard ratios and 95% CIs for coronary heart disease incidence when an interquartile range of urinary arsenic concentrations is compared, by participant characteristics at baseline (n= 3575). Hazard ratios for coronary heart disease incidence (fatal and nonfatal events) were stratified by each subgroup of interest, and associated P values for interaction were obtained from stratified Cox proportional hazards models with log-transformed arsenic (sum of inorganic and methylated arsenic species) as a continuous variable, adjusted for the same covariates as those in model 2 in the main analysis. The interquartile range of urinary arsenic concentrations was 5.8 to 15.7 µg/g creatinine. For coronary heart disease hazard ratios by methylation indices (below and above median proportions of inorganic arsenic, MMA, and DMA), the data set was restricted to participants with detectable inorganic arsenic, MMA, and DMA concentrations (n = 3381). For this subset, the corresponding urinary arsenic interquartile range was 6.1 to 16.2 µg/g creatinine. DMA = dimethylarsinate; HR = hazard ratio; MMA = monomethylarsonate. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Date of download: 5/28/2016 From: Association Between Exposure to Low to Moderate Arsenic Levels and Incident Cardiovascular Disease: A Prospective Cohort Study Ann Intern Med. Published online September 24, doi: / Hazard ratios and 95% CIs for stroke incidence when an interquartile range of urine arsenic concentrations is compared, by participant characteristics at baseline (n= 3575). Hazard ratios for stroke incidence (fatal and nonfatal events) were stratified by each subgroup of interest, and associated P values for interaction were obtained from stratified Cox proportional hazards models with log- transformed arsenic (sum of inorganic and methylated arsenic species) as a continuous variable, adjusted for the same covariates as those in model 2 in the main analysis. The interquartile range of urine arsenic concentrations was 5.8 to 15.7 µg/g creatinine. For stroke incidence hazard ratios by methylation indices (below and above median proportions of inorganic arsenic, MMA, and DMA), the data set was restricted to participants with detectable inorganic arsenic, MMA, and DMA concentrations (n = 3381). For this subset, the corresponding urine arsenic interquartile range was 6.1 to 16.2 µg/g creatinine. DMA = dimethylarsinate; HR = hazard ratio; MMA = monomethylarsonate. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Date of download: 5/28/2016 From: Association Between Exposure to Low to Moderate Arsenic Levels and Incident Cardiovascular Disease: A Prospective Cohort Study Ann Intern Med. Published online September 24, doi: / Hazard ratios for cardiovascular disease incidence and mortality, stratified by study region. The lines represent adjusted hazard ratios based on restricted quadratic splines for the log-transformed sum of inorganic and methylated arsenic species, with knots at the 10th, 50th, and 90th percentiles (3.8, 9.7, and 24.0 µg/g creatinine, respectively). The solid lines indicate participants from Arizona, the dotted lines indicate those from the Dakotas, and the dashed lines indicate those from Oklahoma. The reference was set at the 10th percentile of the arsenic distribution (3.8 µg/g creatinine). Adjustment factors were the same as those for model 2 in Tables 1 and 2. The bars represent a histogram of urinary arsenic distribution among participants (the extreme tails of the histogram were truncated because only 1 participant had a urinary arsenic level 54.6 µg/g creatinine). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Date of download: 5/28/2016 From: Association Between Exposure to Low to Moderate Arsenic Levels and Incident Cardiovascular Disease: A Prospective Cohort Study Ann Intern Med. Published online September 24, doi: / Hazard ratios for cardiovascular disease incidence and mortality, stratified by diabetes status. The lines represent adjusted hazard ratios based on restricted quadratic splines for the log-transformed sum of inorganic and methylated arsenic species, with knots at the 10th, 50th, and 90th percentiles (3.8, 9.7, and 24.0 µg/g creatinine, respectively). The solid lines indicate participants with diabetes at baseline, and the dotted lines indicate those without diabetes at baseline. The reference was set at the 10th percentile of the arsenic distribution (3.8 µg/g creatinine). Adjustment factors were the same as those for model 2 in Tables 1 and 2. The bars represent a histogram of urinary arsenic distribution among participants (the extreme tails of the histogram were truncated because only 1 participant had a urinary arsenic level 54.6 µg/g creatinine). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2024 SlidePlayer.com Inc. All rights reserved.