1. GO-Slim term Cluster frequency cytoplasm 1944 out of 2727 genes, 71.3% 70 out of 97 genes, 72.2% 0.08995522 62 out of 72 genes, 86.1% 0.001430266 39 out of 58 genes, 67.2% 0.08917783 52 out of 58 genes, 89.7% 0.0004678739 41 out of 48 genes, 85.4% 0.01075426 34 out of 46 genes, 73.9% 0.1236741 19 out of 33 genes, 57.6% 0.03379099 20 out of 26 genes, 76.9% 0.1485376 13 out of 21 genes, 61.9% 0.1155542 10 out of 18 genes, 55.6% 0.06832044 2 out of 3 genes, 66.7% 0.4380005 nucleus 1207 out of 2727 genes, 44.3% 40 out of 97 genes, 41.2% 0.0692697 33 out of 72 genes, 45.8% 0.0918465 17 out of 58 genes, 29.3% 0.007081259 32 out of 58 genes, 55.2% 0.0256985 27 out of 48 genes, 56.3% 0.02842495 22 out of 46 genes, 47.8% 0.1047755 9 out of 33 genes, 27.3% 0.01997058 8 out of 26 genes, 30.8% 0.06176291 8 out of 21 genes, 38.1% 0.1506139 1 out of 18 genes, 5.6% 0.0003727414 0.1730197 membrane 668 out of 2727 genes, 24.5% 22 out of 97 genes, 22.7% 0.08947322 17 out of 72 genes, 23.6% 0.1098251 11 out of 58 genes, 19% 0.07969468 21 out of 58 genes, 36.2% 0.01464886 12 out of 48 genes, 25% 0.1327332 8 out of 46 genes, 17.4% 0.07770693 7 out of 33 genes, 21.2% 0.152552 5 out of 26 genes, 19.2% 0.1591873 3 out of 21 genes, 14.3% 0.1241136 7 out of 18 genes, 38.9% 0.07641487 1 out of 3 genes, 33.3% 0.4192006 mitochondrion 621 out of 2727 genes, 22.8% 19 out of 97 genes, 19.6% 0.07650206 15 out of 72 genes, 20.8% 0.1075161 17 out of 58 genes, 29.3% 0.05878285 18 out of 58 genes, 31.0% 0.03914431 11 out of 48 genes, 22.9% 0.1370778 12 out of 46 genes, 26.1% 0.116477 9 out of 33 genes, 27.3% 0.1292514 8 out of 26 genes, 30.8% 0.1080309 6 out of 21 genes, 28.6% 0.1573451 4 out of 18 genes, 22.2% 0.2216058 0.460446 cellular component unknown 382 out of 2727 genes, 14.0% 15 out of 97 genes, 15.5% 0.1042347 5 out of 72 genes, 6.9% 0.02966687 10 out of 58 genes, 17.2% 0.1092581 0.0001428894 4 out of 48 genes, 8.3% 0.09734407 6 out of 46 genes, 13.0% 0.170418 9 out of 33 genes, 27.3% 0.02101395 4 out of 26 genes, 15.4% 0.2091171 7 out of 21 genes, 33.3% 0.01462822 7 out of 18 genes, 38.9% 0.006260992 1 out of 3 genes, 33.3% 0.3109622 plasma membrane 278 out of 2727 genes, 10.2% 9 out of 97 genes, 9.3% 0.1341363 9 out of 72 genes, 12.5% 0.1169195 5 out of 58 genes, 8.6% 0.1703097 16 out of 58 genes, 27.6% 9.906001e-05 5 out of 48 genes, 10.4% 0.1867906 3 out of 46 genes, 6.5% 0.1579044 4 out of 33 genes, 12.1% 0.1967487 2 out of 26 genes, 7.7% 0.2565334 1 out of 21 genes, 4.8% 0.2491131 5 out of 18 genes, 27.8% 0.02303992 0.7241969 endomembrane system 212 out of 2727 genes, 7.8% 5 out of 97 genes, 5.2% 0.1063926 7 out of 72 genes, 9.7% 0.1327814 1 out of 58 genes, 1.7% 0.04346365 5 out of 58 genes, 8.6% 0.1804606 3 out of 48 genes, 6.3% 0.2142044 5 out of 46 genes, 10.9% 0.1418856 1 out of 33 genes, 3.0% 0.1918094 1 out of 26 genes, 3.8% 0.2672345 1 out of 21 genes, 4.8% 0.3240116 2 out of 18 genes, 11.1% 0.2542373 0.7843651 endoplasmic reticulum 193 out of 2727 genes, 7.1% 4 out of 97 genes, 4.1% 0.09311298 7 out of 72 genes, 9.7% 0.1118303 0.01351131 3 out of 58 genes, 5.2% 0.1939212 1 out of 48 genes, 2.1% 0.1064398 5 out of 46 genes, 10.9% 0.1205272 3 out of 33 genes, 9.1% 0.2152458 3 out of 26 genes, 11.5% 0.1710152 2 out of 21 genes, 9.5% 0.2619177 4 out of 18 genes, 22.2% 0.027172 0.8022838 mitochondrial envelope 198 out of 2727 genes, 7.3% 5 out of 97 genes, 5.2% 0.1267612 2 out of 72 genes, 2.8% 0.06727862 5 out of 58 genes, 8.6% 0.1720558 6 out of 58 genes, 10.3% 0.11842 3 out of 48 genes, 6.3% 0.2242971 3 out of 46 genes, 6.5% 0.228957 1 out of 33 genes, 3.0% 0.2142023 2 out of 26 genes, 7.7% 0.2820655 2 out of 21 genes, 9.5% 0.2655105 0.25634820.7975422 ribosome 192 out of 2727 genes, 7.0% 6 out of 97 genes, 6.2% 0.1589539 23 out of 72 genes, 31.9% 1.392438e-10 5 out of 58 genes, 8.6% 0.1672112 4 out of 58 genes, 6.9% 0.2044022 4 out of 48 genes, 8.3% 0.1943047 4 out of 46 genes, 8.7% 0.1884632 5 out of 33 genes, 15.2% 0.05275634 1 out of 26 genes, 3.8% 0.2953035 3 out of 21 genes, 14.3% 0.1248565 0.26755750.8032343 nucleolus 176 out of 2727 genes, 6.5% 5 out of 97 genes, 5.2% 0.1573473 10 out of 72 genes, 13.9% 1.775883e-05 1 out of 58 genes, 1.7% 0.08186191 2 out of 58 genes, 3.4% 0.1636418 2 out of 48 genes, 4.2% 0.2188206 6 out of 46 genes, 13.0% 0.04639154 1 out of 33 genes, 3.0% 0.2516428 0.1750105 1 out of 21 genes, 4.8% 0.3578097 0.29975550.8185458 chromosome 153 out of 2727 genes, 5.6% 5 out of 97 genes, 5.2% 0.1795237 2 out of 72 genes, 2.8% 0.1402314 4 out of 58 genes, 6.9% 0.1880863 1 out of 58 genes, 1.7% 0.1193756 4 out of 48 genes, 8.3% 0.1530262 3 out of 46 genes, 6.5% 0.2259371 1 out of 33 genes, 3.0% 0.2920537 1 out of 26 genes, 3.8% 0.3453083 1 out of 21 genes, 4.8% 0.372463 0.3525060.8408951 site of polarized growth 132 out of 2727 genes, 4.8% 3 out of 97 genes, 3.1% 0.1576862 1 out of 72 genes, 1.4% 0.100761 2 out of 58 genes, 3.4% 0.2418832 2 out of 58 genes, 3.4% 0.2418832 1 out of 48 genes, 2.1% 0.224944 0.1000739 2 out of 33 genes, 6.1% 0.2675614 0.27359490.35138780.4082208 1 out of 3 genes, 33.3% 0.1315906 cytoskeleton 145 out of 2727 genes, 5.3% 6 out of 97 genes, 6.2% 0.1575892 0.01854557 2 out of 58 genes, 3.4% 0.2198019 5 out of 58 genes, 8.6% 0.1079785 0.07092549 2 out of 46 genes, 4.3% 0.2660514 2 out of 33 genes, 6.1% 0.2762479 0.2399513 1 out of 21 genes, 4.8% 0.3756759 0.3728253 1 out of 3 genes, 33.3% 0.1431054 Golgi apparatus 107 out of 2727 genes, 3.9% 4 out of 97 genes, 4.1% 0.2022744 2 out of 72 genes, 2.8% 0.2403127 2 out of 58 genes, 3.4% 0.2729763 2 out of 58 genes, 3.4% 0.2729763 2 out of 48 genes, 4.2% 0.2780361 1 out of 46 genes, 2.2% 0.2984684 0.26477130.35147350.4300969 2 out of 18 genes, 11.1% 0.1242674 0.8868066 cellular bud 101 out of 2727 genes, 3.7% 3 out of 97 genes, 3.1% 0.2185753 0.0636721 3 out of 58 genes, 5.2% 0.198875 1 out of 58 genes, 1.7% 0.2494989 1 out of 48 genes, 2.1% 0.3022589 0.1736314 2 out of 33 genes, 6.1% 0.22631 0.3731176 1 out of 21 genes, 4.8% 0.4513447 0.505861 1 out of 3 genes, 33.3% 0.1031072 vacuole 183 out of 2727 genes, 3.0% 4 out of 97 genes, 4.1% 0.109111 3 out of 72 genes, 4.2% 0.1491484 0.01702304 1 out of 58 genes, 1.7% 0.07265079 4 out of 48 genes, 8.3% 0.1873739 3 out of 46 genes, 6.5% 0.2333072 2 out of 33 genes, 6.1% 0.2775238 0.1628860.2312347 2 out of 18 genes, 11.1% 0.2275341 0.8118233 cell wall 70 out of 2727 genes, 2.6% 2 out of 97 genes, 2.1% 0.2627113 7 out of 72 genes, 9.7% 0.001711684 4 out of 58 genes, 6.9% 0.04438276 7 out of 58 genes, 12.1% 0.0004885197 1 out of 48 genes, 2.1% 0.3654413 2 out of 46 genes, 4.3% 0.2192189 1 out of 33 genes, 3.0% 0.3711599 1 out of 26 genes, 3.8% 0.3505743 0.5780284 1 out of 18 genes, 5.6% 0.2984265 0.9249253 extracellular region 66 out of 2727 genes, 2.4% 1 out of 97 genes, 1.0% 0.2219628 3 out of 72 genes, 4.2% 0.1575416 2 out of 58 genes, 3.4% 0.2486122 5 out of 58 genes, 8.6% 0.0097231 0.3053224 3 out of 46 genes, 6.5% 0.07462957 3 out of 33 genes, 9.1% 0.03651012 1 out of 26 genes, 3.8% 0.3432678 0.59665150.64249280.9291105 cytoplasmic membrane- bounded vesicle 51 out of 2727 genes, 1.9% 1 out of 97 genes, 1.0% 0.2971247 1 out of 72 genes, 1.4% 0.3555227 0.3306487 2 out of 48 genes, 4.2% 0.1667574 0.41655040.53433850.61070650.67170680.71113340.9449173 microtubule organizing center 61 out of 2727 genes, 2.2% 1 out of 97 genes, 1.0% 0.2464688 0.1919193 2 out of 58 genes, 3.4% 0.2358736 4 out of 58 genes, 6.9% 0.03037727 0.3343806 2 out of 46 genes, 4.3% 0.1930001 0.47188440.5538069 1 out of 21 genes, 4.8% 0.3005144 0.66464570.9343597 peroxisome 54 out of 2727 genes, 2% 3 out of 97 genes, 3.1% 0.1776371 2 out of 72 genes, 2.8% 0.2509993 5 out of 58 genes, 8.6% 0.004377619 0.30960410.37965680.39542850.514806 1 out of 26 genes, 3.8% 0.3144533 0.65601110.69687420.9417417 can not be mapped to a GO slim term 15 out of 2727 genes, 0.6% 0.58001630.66870670.7237471 0.7656194 1 out of 46 genes, 2.2% 0.2003149 0.83268590.86582510.89024510.90520410.983583 cell cortex 97 out of 2727 genes, 3.6% 4 out of 97 genes, 4.1% 0.1947821 0.07115377 1 out of 58 genes, 1.7% 0.2615801 2 out of 58 genes, 3.4% 0.2780432 0.17309490.186337 2 out of 33 genes, 6.1% 0.2187938 0.38825290.46606130.5199581 1 out of 3 genes, 33.3% 0.09932574 Hyphal tip 32 out of 2727 genes, 1.2% 0.31169020.42265050.5006104 2 out of 58 genes, 3.4% 0.1179153 1 out of 48 genes, 2.1% 0.3275286 0.5783726 1 out of 33 genes, 3.0% 0.2679885 0.73467620.77973520.80804360.9651953 Cellular component

2. GO-Slim termCluster frequency regulation of biological process 723 out of 2727 genes, 26.5% 24 out of 97 genes, 24.7% 0.08765662 19 out of 72 genes, 26.4% 0.1075577 7 out of 58 genes, 12.1% 0.003916686 20 out of 58 genes, 34.5% 0.04449496 17 out of 48 genes, 35.4% 0.0474458 12 out of 46 genes, 26.1% 0.1337743 8 out of 33 genes, 24.2% 0.1540724 3 out of 26 genes, 11.5% 0.04011472 5 out of 21 genes, 23.8% 0.1934844 2 out of 18 genes, 11.1% 0.07740047 1 out of 3 genes, 33.3% 0.4297944 organelle organization 580 out of 2727 genes, 21.3% 18 out of 97 genes, 18.6% 0.08391737 12 out of 72 genes, 16.7% 0.07722191 10 out of 58 genes, 17.2% 0.1026475 12 out of 58 genes, 20.7% 0.1289601 9 out of 48 genes, 18.8% 0.1339023 8 out of 46 genes, 17.4% 0.1240838 6 out of 33 genes, 18.2% 0.1277373 5 out of 26 genes, 19.2% 0.1895361 5 out of 21 genes, 23.8% 0.1937745 0.013305460.4878784 transport 514 out of 2727 genes, 18.8% 14 out of 97 genes, 14.4% 0.05870324 18 out of 72 genes, 25% 0.04689415 2 out of 58 genes, 3.4% 0.0004455719 14 out of 58 genes, 24.1% 0.07409093 11 out of 48 genes, 22.9% 0.1067861 11 out of 46 genes, 23.9% 0.09554217 3 out of 33 genes, 9.1% 0.06882279 6 out of 26 genes, 23.1% 0.1590595 2 out of 21 genes, 9.5% 0.1407456 4 out of 18 genes, 22.2% 0.2081727 0.5342909 response to stress 489 out of 2727 genes, 17.9% 20 out of 97 genes, 20.6% 0.08017397 14 out of 72 genes, 19.4% 0.1131963 10 out of 58 genes, 17.2% 0.1375848 11 out of 58 genes, 19% 0.1312539 14 out of 48 genes, 29.2% 0.02021737 14 out of 46 genes, 30.4% 0.01485237 4 out of 33 genes, 12.1% 0.1372345 10 out of 26 genes, 38.5% 0.007527067 3 out of 21 genes, 14.3% 0.2192618 4 out of 18 genes, 22.2% 0.1995483 1 out of 3 genes, 33.3% 0.362559 RNA metabolic process 415 out of 2727 genes, 15.2% 11 out of 97 genes, 11.3% 0.06837149 14 out of 72 genes, 19.4% 0.07435793 4 out of 58 genes, 6.9% 0.02974152 6 out of 58 genes, 10.3% 0.09365102 9 out of 48 genes, 18.8% 0.1181468 9 out of 46 genes, 19.6% 0.107793 3 out of 33 genes, 9.1% 0.1356002 3 out of 26 genes, 11.5% 0.2061198 1 out of 21 genes, 4.8% 0.1170505 0.05070540.6092875 biological process unknown 438 out of 2727 genes, 16.1% 15 out of 97 genes, 15.5% 0.1118509 6 out of 72 genes, 8.3% 0.02481678 16 out of 58 genes, 27.6% 0.009598395 2 out of 58 genes, 3.4% 0.002193818 4 out of 48 genes, 8.3% 0.05762602 10 out of 46 genes, 21.7% 0.1115576 12 out of 33 genes, 36.4% 0.00251817 2 out of 26 genes, 7.7% 0.1249969 5 out of 21 genes, 23.8% 0.1323176 4 out of 18 genes, 22.2% 0.1759869 1 out of 3 genes, 33.3% 0.3397189 response to chemical stimulus 406 out of 2727 genes, 14.9% 18 out of 97 genes, 18.6% 0.06408205 12 out of 72 genes, 16.7% 0.1162264 9 out of 58 genes, 15.5% 0.143591 13 out of 58 genes, 22.4% 0.03889899 6 out of 48 genes, 12.5% 0.1541787 10 out of 46 genes, 21.7% 0.06562541 3 out of 33 genes, 9.1% 0.1427457 6 out of 26 genes, 23.1% 0.09980627 2 out of 21 genes, 9.5% 0.2178142 2 out of 18 genes, 11.1% 0.2576659 1 out of 3 genes, 33.3% 0.3237673 filamentous growth 309 out of 2727 genes, 11.3% 11 out of 97 genes, 11.3% 0.1290855 9 out of 72 genes, 12.5% 0.1360816 3 out of 58 genes, 5.2% 0.05911826 7 out of 58 genes, 12.1% 0.1581699 6 out of 48 genes, 12.5% 0.1678329 4 out of 46 genes, 8.7% 0.1729487 0.01843363 4 out of 26 genes, 15.4% 0.1756073 2 out of 21 genes, 9.5% 0.2752622 3 out of 18 genes, 16.7% 0.1960521 1 out of 3 genes, 33.3% 0.2674454 cell cycle 285 out of 2727 genes, 10.5% 8 out of 97 genes, 8.2% 0.1119302 2 out of 72 genes, 2.8% 0.01163136 3 out of 58 genes, 5.2% 0.08027861 8 out of 58 genes, 13.8% 0.110055 4 out of 48 genes, 8.3% 0.1814118 4 out of 46 genes, 8.7% 0.1898618 5 out of 33 genes, 15.2% 0.1350463 3 out of 26 genes, 11.5% 0.2355304 1 out of 21 genes, 4.8% 0.2411221 0.13621740.7180022 cellular protein modification process 270 out of 2727 genes, 9.9% 6 out of 97 genes, 6.2% 0.06944819 2 out of 72 genes, 2.8% 0.01612208 4 out of 58 genes, 6.9% 0.146511 5 out of 58 genes, 8.6% 0.1750819 4 out of 48 genes, 8.3% 0.1915518 4 out of 46 genes, 8.7% 0.197991 1 out of 33 genes, 3.0% 0.1152413 3 out of 26 genes, 11.5% 0.2305648 1 out of 21 genes, 4.8% 0.2583171 0.15214950.7313201 can not be mapped to a GO slim term 231 out of 2727 genes, 8.5% 9 out of 97 genes, 9.3% 0.1353777 3 out of 72 genes, 4.2% 0.07942263 8 out of 58 genes, 13.8% 0.06043604 10 out of 58 genes, 17.2% 0.01359665 0.01374115 1 out of 46 genes, 2.2% 0.07133886 3 out of 33 genes, 9.1% 0.2345379 0.09902022 2 out of 21 genes, 9.5% 0.2815265 4 out of 18 genes, 22.2% 0.0453398 0.7667152 ribosome biogenesis 214 out of 2727 genes, 7.8% 5 out of 97 genes, 5.2% 0.1035427 19 out of 72 genes, 26.4% 1.007096e-06 1 out of 58 genes, 1.7% 0.04190712 4 out of 58 genes, 6.9% 0.1966774 3 out of 48 genes, 6.3% 0.2125371 7 out of 46 genes, 15.2% 0.03994138 3 out of 33 genes, 9.1% 0.2286232 0.1182373 1 out of 21 genes, 4.8% 0.3218861 0.22858520.7824946 response to drug 186 out of 2727 genes, 6.8% 4 out of 97 genes, 4.1% 0.1041856 6 out of 72 genes, 8.3% 0.1504297 4 out of 58 genes, 6.9% 0.2046059 5 out of 58 genes, 8.6% 0.1616452 3 out of 48 genes, 6.3% 0.230284 2 out of 46 genes, 4.3% 0.2155032 1 out of 33 genes, 3.0% 0.2343496 3 out of 26 genes, 11.5% 0.1630499 0.22555330.2792286 1 out of 3 genes, 33.3% 0.177785 translation 198 out of 2727 genes, 7.3% 4 out of 97 genes, 4.1% 0.08561055 25 out of 72 genes, 34.7% 5.087252e-12 2 out of 58 genes, 3.4% 0.1269139 6 out of 58 genes, 10.3% 0.11842 5 out of 48 genes, 10.4% 0.1359777 4 out of 46 genes, 8.7% 0.1929839 3 out of 33 genes, 9.1% 0.2190525 2 out of 26 genes, 7.7% 0.2820655 1 out of 21 genes, 4.8% 0.3382901 0.25634820.7975422 DNA metabolic process 172 out of 2727 genes, 6.3% 4 out of 97 genes, 4.1% 0.1278617 3 out of 72 genes, 4.2% 0.167278 3 out of 58 genes, 5.2% 0.216753 2 out of 58 genes, 3.4% 0.1707613 5 out of 48 genes, 10.4% 0.1039964 3 out of 46 genes, 6.5% 0.2333162 1 out of 33 genes, 3.0% 0.2586472 2 out of 26 genes, 7.7% 0.2721687 2 out of 21 genes, 9.5% 0.2433182 1 out of 18 genes, 5.6% 0.3761539 0.8224038 vesicle-mediated transport 165 out of 2727 genes, 6.1% 6 out of 97 genes, 6.2% 0.1686464 2 out of 72 genes, 2.8% 0.1171211 1 out of 58 genes, 1.7% 0.09834476 3 out of 58 genes, 5.2% 0.2226173 4 out of 48 genes, 8.3% 0.1687106 1 out of 46 genes, 2.2% 0.1666261 1 out of 33 genes, 3.0% 0.2709684 1 out of 26 genes, 3.8% 0.3311506 1 out of 21 genes, 4.8% 0.3657096 0.3239780.8291845 carbohydrate metabolic process 157 out of 2727 genes, 5.8% 9 out of 97 genes, 9.3% 0.05314433 6 out of 72 genes, 8.3% 0.1144271 9 out of 58 genes, 15.5% 0.003724666 7 out of 58 genes, 12.1% 0.02989341 2 out of 48 genes, 4.2% 0.2455402 2 out of 46 genes, 4.3% 0.2537995 3 out of 33 genes, 9.1% 0.176704 6 out of 26 genes, 23.1% 0.002433068 0.2865194 1 out of 18 genes, 5.6% 0.3793936 1 out of 3 genes, 33.3% 0.1535114 protein catabolic process 130 out of 2727 genes, 4.8% 2 out of 97 genes, 2.1% 0.1000979 6 out of 72 genes, 8.3% 0.07266756 1 out of 58 genes, 1.7% 0.1693565 3 out of 58 genes, 5.2% 0.2303207 5 out of 48 genes, 10.4% 0.05102243 3 out of 46 genes, 6.5% 0.2030997 2 out of 33 genes, 6.1% 0.2657932 0.27915760.35714150.41394010.8636475 lipid metabolic process 119 out of 2727 genes, 4.4% 5 out of 97 genes, 5.2% 0.1713347 3 out of 72 genes, 4.2% 0.2309837 6 out of 58 genes, 10.3% 0.02666651 0.07309953 4 out of 48 genes, 8.3% 0.09910549 0.126190.2273383 1 out of 26 genes, 3.8% 0.3734244 2 out of 21 genes, 9.5% 0.1718262 1 out of 18 genes, 5.6% 0.3693511 0.8746726 cytoskeleton organization 113 out of 2727 genes, 4.1% 4 out of 97 genes, 4.1% 0.2031295 2 out of 72 genes, 2.8% 0.2279022 0.08364493 5 out of 58 genes, 8.6% 0.05882924 2 out of 48 genes, 4.2% 0.2789375 1 out of 46 genes, 2.2% 0.2840568 2 out of 33 genes, 6.1% 0.245844 0.33103950.4098040.46570410.8807257 pathogenesis 113 out of 2727 genes, 4.1% 7 out of 97 genes, 7.2% 0.05906744 5 out of 72 genes, 6.9% 0.1006052 4 out of 58 genes, 6.9% 0.1279831 3 out of 58 genes, 5.2% 0.2166193 0.1288019 4 out of 46 genes, 8.7% 0.08108772 1 out of 33 genes, 3.0% 0.3543611 1 out of 26 genes, 3.8% 0.3756639 0.409804 2 out of 18 genes, 11.1% 0.1336555 1 out of 3 genes, 33.3% 0.1143055 signal transduction 103 out of 2727 genes, 3.8% 3 out of 97 genes, 3.1% 0.2156428 4 out of 72 genes, 5.6% 0.1544041 2 out of 58 genes, 3.4% 0.2756573 3 out of 58 genes, 5.2% 0.2022989 1 out of 48 genes, 2.1% 0.297307 0.16760050.27852820.36576430.4441534 1 out of 18 genes, 5.6% 0.3548334 1 out of 3 genes, 33.3% 0.1049888 generation of precursor metabolites and energy 80 out of 2727 genes, 2.9% 6 out of 97 genes, 6.2% 0.04072934 2 out of 72 genes, 2.8% 0.2771062 3 out of 58 genes, 5.2% 0.1526399 6 out of 58 genes, 10.3% 0.005034715 3 out of 48 genes, 6.3% 0.1145895 1 out of 46 genes, 2.2% 0.3553586 0.3721418 2 out of 26 genes, 7.7% 0.1372095 0.5338619 1 out of 18 genes, 5.6% 0.31982 0.9145174 cell wall organization 81 out of 2727 genes, 3% 3 out of 97 genes, 3.1% 0.2313047 1 out of 72 genes, 1.4% 0.2508951 2 out of 58 genes, 3.4% 0.2727176 4 out of 58 genes, 6.9% 0.06422467 1 out of 48 genes, 2.1% 0.3473607 2 out of 46 genes, 4.3% 0.2446698 1 out of 33 genes, 3.0% 0.3757971 0.45491230.52962650.5801436 1 out of 3 genes, 33.3% 0.08395456 cytokinesis 68 out of 2727 genes, 2.5% 2 out of 97 genes, 2.1% 0.2665152 0.1584135 1 out of 58 genes, 1.7% 0.3449256 3 out of 58 genes, 5.2% 0.1197128 0.2944047 1 out of 46 genes, 2.2% 0.3708727 2 out of 33 genes, 6.1% 0.1506815 0.51704830.58726960.63382850.9270163 cellular homeostasis 78 out of 2727 genes, 2.9% 4 out of 97 genes, 4.1% 0.1585042 0.12032840.1824533 3 out of 58 genes, 5.2% 0.147395 1 out of 48 genes, 2.1% 0.3529581 4 out of 46 genes, 8.7% 0.03154431 0.3815917 1 out of 26 genes, 3.8% 0.3621493 1 out of 21 genes, 4.8% 0.3379611 4 out of 18 genes, 22.2% 0.001289646 1 out of 3 genes, 33.3% 0.08102859 hyphal growth 75 out of 2727 genes, 2.8% 1 out of 97 genes, 1.0% 0.1811171 1 out of 72 genes, 1.4% 0.2734318 1 out of 58 genes, 1.7% 0.3268325 4 out of 58 genes, 6.9% 0.05308977 1 out of 48 genes, 2.1% 0.3580932 0.27425260.39620430.48264170.55552730.6043643 1 out of 3 genes, 33.3% 0.07808871 cell development 72 out of 2727 genes, 2.6% 2 out of 97 genes, 2.1% 0.2585184 1 out of 72 genes, 1.4% 0.2847409 0.2083349 3 out of 58 genes, 5.2% 0.1310303 2 out of 48 genes, 4.2% 0.2319525 0.2890219 1 out of 33 genes, 3.0% 0.3726225 3 out of 26 genes, 11.5% 0.02539518 0.56892570.61682980.9228374 protein folding 64 out of 2727 genes, 2.3% 1 out of 97 genes, 1.0% 0.2316396 10 out of 72 genes, 13.9% 3.741014e-06 0.2485258 2 out of 58 genes, 3.4% 0.2438088 3 out of 48 genes, 6.3% 0.07638488 3 out of 46 genes, 6.5% 0.07019858 1 out of 33 genes, 3.0% 0.3649007 0.5377556 2 out of 21 genes, 9.5% 0.07344799 0.65126890.9312078 cellular respiration 50 out of 2727 genes, 1.8% 3 out of 97 genes, 3.1% 0.1619568 0.2591869 2 out of 58 genes, 3.4% 0.1993197 1 out of 58 genes, 1.7% 0.3740903 2 out of 48 genes, 4.2% 0.1630192 1 out of 46 genes, 2.2% 0.370371 0.5410077 1 out of 26 genes, 3.8% 0.302302 0.67701780.71594740.9459774 interspecies interaction between organisms 61 out of 2727 genes, 2.2% 2 out of 97 genes, 2.1% 0.2760911 4 out of 72 genes, 5.6% 0.05440682 1 out of 58 genes, 1.7% 0.3600176 3 out of 58 genes, 5.2% 0.09949271 0.3343806 1 out of 46 genes, 2.2% 0.3748492 0.4718844 2 out of 26 genes, 7.7% 0.09441079 0.6207347 1 out of 18 genes, 5.6% 0.275493 0.9343597 biofilm formation 53 out of 2727 genes, 1.9% 3 out of 97 genes, 3.1% 0.1738808 3 out of 72 genes, 4.2% 0.1133814 1 out of 58 genes, 1.7% 0.3717324 1 out of 58 genes, 1.7% 0.3717324 0.3865964 1 out of 46 genes, 2.2% 0.3731188 1 out of 33 genes, 3.0% 0.3450592 2 out of 26 genes, 7.7% 0.07641617 0.66120380.7015970.9427994 conjugation 49 out of 2727 genes, 1.8% 1 out of 97 genes, 1.0% 0.3070997 1 out of 72 genes, 1.4% 0.3604431 0.345453 2 out of 58 genes, 3.4% 0.3745813 0.4156185 1 out of 46 genes, 2.2% 0.3691669 0.5477575 1 out of 26 genes, 3.8% 0.2990477 0.6823687 1 out of 18 genes, 5.6% 0.2389097 1 out of 3 genes, 33.3% 0.05202341 nucleus organization 36 out of 2727 genes, 1.3% 0.2691587 1 out of 72 genes, 1.4% 0.375186 1 out of 58 genes, 1.7% 0.3637465 1 out of 58 genes, 1.7% 0.3637465 1 out of 48 genes, 2.1% 0.3434167 2 out of 46 genes, 4.3% 0.1005196 0.64329250.70671740.75570110.78665930.9609024 cell adhesion 29 out of 2727 genes, 1.1% 4 out of 97 genes, 4.1% 0.01495519 2 out of 72 genes, 2.8% 0.3643399 1 out of 58 genes, 1.7% 0.3403158 0.53434850.5958995 1 out of 46 genes, 2.2% 0.3062245 0.7012349 1 out of 26 genes, 3.8% 0.2133485 0.79823660.82444080.9684234 Cell budding 23 out of 2727 genes, 0.8% 2 out of 97 genes, 2.1% 0.150007 0.5390476 1 out of 58 genes, 1.7% 0.3067471 0.6086653 1 out of 48 genes, 2.1% 0.2757184 0.67510820.75490120.17891460.83650130.85818270.9749011 growth of unicellular organism as a thread of attached cells 35 out of 2727 genes, 1.3% 1 out of 97 genes, 1.0% 0.3651584 0.38966080.4689681 1 out of 58 genes, 1.7% 0.3612923 1 out of 48 genes, 2.1% 0.3398102 0.54924850.65127620.71360960.76164260.79195470.9619744 Vitamin metabolic process 22 out of 2727 genes, 0.8% 0.44935470.553788 1 out of 58 genes, 1.7% 0.2997261 1 out of 58 genes, 1.7% 0.2997261 2 out of 48 genes, 4.2% 0.04981289 0.68678740.7642245 2 out of 26 genes, 7.7% 0.01691241 0.84304620.86393160.9759836 Pseudohyphal growth 17 out of 2727 genes, 0.6% 0.53926010.63366510.6931158 1 out of 58 genes, 1.7% 0.2575998 0.73875280.74821320.81254110.84930020.87650890.89322580.9814077 Biological process

3. GO-Slim term Cluster frequency molecular function unknown 650 out of 2727 genes, 23.8% 19 out of 97 genes, 19.6% 0.06125701 10 out of 72 genes, 13.9% 0.01416744 18 out of 58 genes, 31.0% 0.051425 3 out of 58 genes, 5.2% 0.0001167355 6 out of 48 genes, 12.5% 0.023726 17 out of 46 genes, 37% 0.01642314 11 out of 33 genes, 33.3% 0.0682042 2 out of 26 genes, 7.7% 0.02640552 7 out of 21 genes, 33.3% 0.1124611 5 out of 18 genes, 27.8% 0.1919409 0.4416767 hydrolase activity 451 out of 2727 genes, 16.5% 11 out of 97 genes, 11.3% 0.0436196 14 out of 72 genes, 19.4% 0.09651415 6 out of 58 genes, 10.3% 0.06778559 11 out of 58 genes, 19% 0.1187687 13 out of 48 genes, 27.1% 0.02336686 8 out of 46 genes, 17.4% 0.1530125 3 out of 33 genes, 9.1% 0.1084242 7 out of 26 genes, 26.9% 0.0715602 2 out of 21 genes, 9.5% 0.1850561 1 out of 18 genes, 5.6% 0.1372302 2 out of 3 genes, 66.7% 0.06840771 transferase activity 367 out of 2727 genes, 13.5% 12 out of 97 genes, 12.4% 0.1179196 9 out of 72 genes, 12.5% 0.1384322 9 out of 58 genes, 15.5% 0.1307759 7 out of 58 genes, 12.1% 0.1525229 5 out of 48 genes, 10.4% 0.1516608 4 out of 46 genes, 8.7% 0.1234196 2 out of 33 genes, 6.1% 0.1076281 3 out of 26 genes, 11.5% 0.228976 2 out of 21 genes, 9.5% 0.244503 2 out of 18 genes, 11.1% 0.2750335 0.6480466 protein binding 349 out of 2727 genes, 12.8% 11 out of 97 genes, 11.3% 0.1167167 12 out of 72 genes, 16.7% 0.08042734 2 out of 58 genes, 3.4% 0.01209097 13 out of 58 genes, 22.4% 0.01586873 8 out of 48 genes, 16.7% 0.1141001 5 out of 46 genes, 10.9% 0.172544 4 out of 33 genes, 12.1% 0.1883665 1 out of 26 genes, 3.8% 0.107702 4 out of 21 genes, 19.0% 0.1569353 0.084311780.6629946 oxidoreductase activity 250 out of 2727 genes, 9.2% 12 out of 97 genes, 12.4% 0.07100929 4 out of 72 genes, 5.6% 0.104433 12 out of 58 genes, 20.7% 0.003487253 6 out of 58 genes, 10.3% 0.1636815 3 out of 48 genes, 6.3% 0.1763552 5 out of 46 genes, 10.9% 0.1737108 2 out of 33 genes, 6.1% 0.2256463 8 out of 26 genes, 30.8% 0.001306258 3 out of 21 genes, 14.3% 0.1821218 5 out of 18 genes, 27.8% 0.01565049 0.7493321 RNA binding 213 out of 2727 genes, 7.8% 6 out of 97 genes, 6.2% 0.1381624 10 out of 72 genes, 13.9% 0.02848397 3 out of 58 genes, 5.2% 0.1680364 4 out of 58 genes, 6.9% 0.1972378 7 out of 48 genes, 14.6% 0.04600534 4 out of 46 genes, 8.7% 0.201333 4 out of 33 genes, 12.1% 0.1445962 3 out of 26 genes, 11.5% 0.1917091 1 out of 21 genes, 4.8% 0.3229512 0.23023360.7834295 DNA binding 197 out of 2727 genes, 7.2% 9 out of 97 genes, 9.3% 0.1055553 1 out of 72 genes, 1.4% 0.02421609 4 out of 58 genes, 6.9% 0.203564 5 out of 58 genes, 8.6% 0.1712994 4 out of 48 genes, 8.3% 0.1974424 5 out of 46 genes, 10.9% 0.125239 2 out of 33 genes, 6.1% 0.2708714 3 out of 26 genes, 11.5% 0.1754085 1 out of 21 genes, 4.8% 0.3392634 0.25818510.798489 structural molecule activity 191 out of 2727 genes, 7.0% 3 out of 97 genes, 3.1% 0.0532019 23 out of 72 genes, 31.9% 1.249784e-10 3 out of 58 genes, 5.2% 0.19635 6 out of 58 genes, 10.3% 0.1100181 2 out of 48 genes, 4.2% 0.1960894 4 out of 46 genes, 8.7% 0.1876446 4 out of 33 genes, 12.1% 0.1201419 0.150018 1 out of 21 genes, 4.8% 0.3449501 0.26947010.8041857 transporter activity 172 out of 2727 genes, 6.3% 7 out of 97 genes, 7.2% 0.147586 3 out of 72 genes, 4.2% 0.167278 0.02192557 6 out of 58 genes, 10.3% 0.08607299 5 out of 48 genes, 10.4% 0.1039964 5 out of 46 genes, 10.9% 0.09468276 0.1149695 2 out of 26 genes, 7.7% 0.2721687 0.253255 4 out of 18 genes, 22.2% 0.01917101 0.8224038 can not be mapped to a GO slim term 124 out of 2727 genes, 4.5% 8 out of 97 genes, 8.2% 0.04096868 1 out of 72 genes, 1.4% 0.1181286 3 out of 58 genes, 5.2% 0.2269756 1 out of 58 genes, 1.7% 0.1845147 2 out of 48 genes, 4.2% 0.276412 2 out of 46 genes, 4.3% 0.278387 3 out of 33 genes, 9.1% 0.1272763 0.2965059 1 out of 21 genes, 4.8% 0.3779939 0.43155550.8696496 enzyme regulator activity 126 out of 2727 genes, 4.6% 3 out of 97 genes, 3.1% 0.1708903 4 out of 72 genes, 5.6% 0.190598 0.06244003 3 out of 58 genes, 5.2% 0.2282662 5 out of 48 genes, 10.4% 0.04653579 1 out of 46 genes, 2.2% 0.2525982 2 out of 33 genes, 6.1% 0.2618981 1 out of 26 genes, 3.8% 0.3695814 4 out of 21 genes, 19.0% 0.01192453 2 out of 18 genes, 11.1% 0.153542 1 out of 3 genes, 33.3% 0.1261909 ligase activity 105 out of 2727 genes, 3.9% 2 out of 97 genes, 2.1% 0.1646952 4 out of 72 genes, 5.6% 0.158398 4 out of 58 genes, 6.9% 0.1122534 6 out of 58 genes, 10.3% 0.01638219 5 out of 48 genes, 10.4% 0.0260731 0.1617747 2 out of 33 genes, 6.1% 0.2333263 3 out of 26 genes, 11.5% 0.05979517 0.43707140.49212550.8888398 peptidase activity 68 out of 2727 genes, 2.5% 1 out of 97 genes, 1.0% 0.2124829 0.1584135 1 out of 58 genes, 1.7% 0.3449256 2 out of 58 genes, 3.4% 0.2530294 2 out of 48 genes, 4.2% 0.2216792 2 out of 46 genes, 4.3% 0.2138014 2 out of 33 genes, 6.1% 0.1506815 1 out of 26 genes, 3.8% 0.3470544 0.58726960.63382850.9270163 lipid binding 65 out of 2727 genes, 2.4% 3 out of 97 genes, 3.1% 0.2108357 2 out of 72 genes, 2.8% 0.2723219 1 out of 58 genes, 1.7% 0.3518371 1 out of 58 genes, 1.7% 0.3518371 2 out of 48 genes, 4.2% 0.213282 0.3265753 2 out of 33 genes, 6.1% 0.1425072 0.53250520.60139580.64686680.9301587 protein kinase activity 62 out of 2727 genes, 2.3% 1 out of 97 genes, 1.0% 0.2414887 0.1867362 1 out of 58 genes, 1.7% 0.358096 2 out of 58 genes, 3.4% 0.2386163 0.3283602 1 out of 46 genes, 2.2% 0.3745633 0.13418850.548406 1 out of 21 genes, 4.8% 0.66015820.9333082 lyase activity 56 out of 2727 genes, 2.1% 6 out of 97 genes, 6.2% 0.01014885 4 out of 72 genes, 5.6% 0.0435666 4 out of 58 genes, 6.9% 0.02368059 3 out of 58 genes, 5.2% 0.08503889 1 out of 48 genes, 2.1% 0.3750717 0.38193310.11721760.5815880.30314950.68751850.9396286 helicase activity 51 out of 2727 genes, 1.9% 1 out of 97 genes, 1.0% 0.2971247 3 out of 72 genes, 4.2% 0.1061996 1 out of 58 genes, 1.7% 0.3734475 0.3306487 1 out of 48 genes, 2.1% 0.3732528 2 out of 46 genes, 4.3% 0.1587601 0.5343385 1 out of 26 genes, 3.8% 0.3054685 0.67170680.71113340.9449173 nucleotidyltransferase activity 44 out of 2727 genes, 1.6% 0.20058080.30518480.3853733 3 out of 48 genes, 6.3% 0.03409655 1 out of 46 genes, 2.2% 0.360775 0.58275030.65383730.7097330.74548390.9523548 isomerase activity 44 out of 2727 genes, 1.6% 3 out of 97 genes, 3.1% 0.1355759 1 out of 72 genes, 1.4% 0.3701475 2 out of 58 genes, 3.4% 0.1747112 2 out of 58 genes, 3.4% 0.1747112 0.4549091 1 out of 46 genes, 2.2% 0.360775 0.5827503 1 out of 26 genes, 3.8% 0.2814108 0.7097330.74548390.9523548 phosphatase activity 44 out of 2727 genes, 1.6% 3 out of 97 genes, 3.1% 0.1355759 1 out of 72 genes, 1.4% 0.3701475 1 out of 58 genes, 1.7% 0.3745136 2 out of 58 genes, 3.4% 0.1747112 2 out of 48 genes, 4.2% 0.1396688 1 out of 46 genes, 2.2% 0.360775 0.5827503 1 out of 26 genes, 3.8% 0.2814108 0.7097330.7454839 1 out of 3 genes, 33.3% 0.04688953 protein binding transcription factor activity 53 out of 2727 genes, 1.9% 1 out of 97 genes, 1.0% 0.2870157 0.23882380.3164684 2 out of 48 genes, 4.2% 0.1740847 0.402350.5212386 1 out of 26 genes, 3.8% 0.3115428 0.66120380.7015979427994 Molecular function