1. INSECTICIDE UPDATE 2006 Alex Latchininsky and Scott Schell UW Extension Entomologists WY Commercial Pesticide Applicator Recertification School, Casper, 1/18/06

2. Disclaimer Trade or brand names used in this presentation are used only for the purpose of educational information. Trade or brand names used in this presentation are used only for the purpose of educational information. No product endorsement is implied. No product endorsement is implied.

3. Safety – First! Always wear protective gear when applying pesticides

4. Insecticide Product Labels Learn to read the small print.Learn to read the small print. Look for the ACTIVE INGREDIENT,Look for the ACTIVE INGREDIENT, NOT the brand name. One and the same active ingredient can be commercialized under multiple brand names.One and the same active ingredient can be commercialized under multiple brand names. Insecticide label is THE LAW, always follow its instructions.Insecticide label is THE LAW, always follow its instructions.

5. Bye-bye, “good” old OPs

6. Organophosphate insecticides are being phased out Chlorpyrifos (Dursban) – Sales stopped in December 2001 Diazinon – Completely withdrawn from stores in December 2004 Malathion – Under re-registration Orthene (Acephate) – limited availability

7. Organophosphates Insecticides of this chemical class were developed in the 1940s-50s from German nerve gases. Broad-spectrum poisons that inhibit cholinesterase. Hazardous for many groups of non-target organisms (honey bees, birds, fish…) Some, like ethyl parathion, are very hazardousto mammals.

8. Diazinon Diazinon was introduced in 1952. Cheap, can use it on almost everything for anything. Along with related OP insecticides it was produced and sold by the millions of pounds per year in US. A lot of sources of exposure for people.

9. Diazinon failed to comply with FQPA Food Quality Protection Act of 1996 requires re-registration of all pesticides Human Exposure, via dietary and non-dietary sources are included in a “risk cup” “The cup holds the total amount (100%) of a given pesticide that a person could be exposed to every day, for 70 years, without additional health risks.”

10. Most Common Diazinon Replacements Synthetic Pyrethroids Allethrin ( 1st generation – 1949s ) Resmethrin (2nd generation – 1960s) Permethrin (3 rd generation – 1970s) Esfenvalerate (3 rd generation) Deltamethrin (4 th generation – 1980s) Cyfluthrin (Newest 4 th generation - 1998)

11. Synthetic Pyrethroids Chemical analogs of the toxic substance present in the Pyrethrum plant (Aster family). Fast knock-down, low persistence (4-7d on foliage). Fast break-down in soil and water. Broad-spectrum (Na + channel blockers in CNS). Generally, less hazardous for mammals. Still highly hazardous for honey bees.

12. Organophosphates vs. Pyrethroids: non-target hazards Mammals Honey Bees Birds Fish Mammals Honey Bees Birds Fish Organophosphates Organophosphates *DiazinonHVHVHH *ChlorpyrifosHVHVHVH *Methyl ParathionVHVHVHVH MalathionLVHHM OrtheneMVHML Pyrethroids Pyrethroids PermethrinLVHLVH EsfenvalerateHHLVH CyfluthrinLHLH ResmethrinMHLH

13. Is Sevin® (Carbaryl) a good Diazinon replacement? Many carbaryl products are available for insect control: Sevin Lawn granules® Sevin Dust (Eliminator®) Sevin Bug Killer® Sevin Ant Bait® Sevin XLR Plus® Same mode of action as OP. Re-registration changes? Non-target hazards Mammals Honey Bees Birds Fish Diazinon H VH VH H Carbaryl M/HVH M L

14. Insect pest control products for the 21 st century

15. BIORATIONAL INSECTICIDES: WHAT ARE THEY? No single, clear definition. EPA identifies biorational pesticides as having “fundamentally different modes of action” and “lower risks of adverse effects” than conventional (i.e. neurotoxin) pesticides.

16. Types of Biorational Pesticides Insect Growth Regulators (IGR)Insect Growth Regulators (IGR) Juvenile Hormone AnalogsJuvenile Hormone Analogs PrecocenesPrecocenes Chitin Synthesis InhibitorsChitin Synthesis Inhibitors –Low toxicity for birds, mammals, reptiles but effects non-target arthropods and insects. –Only immature pests are killed. IGR can also effect arthropod eggs and embryogenesis.

17. Diflubenzuron (Dimilin ® 2L) PROS: Safety (bees, people, etc.) Residual (strips) Reliable results Temperature range CONS: Timing!!! (IGR = nymphs) Less familiar (since ‘97) High cost/unit Harm to aquatic invertebrates – R.U.P. Benzoyl-Urea; IGR (chitin synthesis inhibitor) $230

18. Insects are killed when they grow to a next developmental stage Normal molt Unsuccessful molt after Dimilin application

19. I II III IV V recommended TIMING is critical when applying Dimilin not recommended ineffective

20. Pyriproxyfen (Knack®) sub-lethal effects Treated Untreated Treated Untreated

21. Other Types of Biorational Pesticides BotanicalsBotanicals Natural toxicants like nicotineNatural toxicants like nicotine Neem (azadirachtin is less toxic but still useful in greenhouses, UV light breaks it down)Neem (azadirachtin is less toxic but still useful in greenhouses, UV light breaks it down)

22. Bacterial Fermentation ProductsBacterial Fermentation ProductsSpinosad (has certified organic formulations) Avermectin Other Types of Biorational Pesticides

23. SPINOSAD Spinosad– a toxin mixture produced from fermentation of a soil bacterium, Saccharopolyspora spinosa Disrupts binding of acetylcholine receptors Brand names: Ferti-lome Borer, Bagworm, Leafminer & Tent Caterpillar Spray®; Intruder®; Success® Rapid contact and ingestion activity

24. MicrobialsMicrobials Bacteria (Bt varieties mostly)Bacteria (Bt varieties mostly) Fungi (Metarhizium anisopliae and Beauveria bassiana)Fungi (Metarhizium anisopliae and Beauveria bassiana) VirusesViruses NematodesNematodes Genetically modified plants (produce Bt toxins)Genetically modified plants (produce Bt toxins) –High selectivity –Low toxicity for non-target animals –Sensitive to environmental conditions, many have failed commercially Other Types of Biorational Pesticides

25. Fungal pathogens

26. White Satin Moth in Wyoming

27. Damage Pupa

28. Biological control with Bt Pros: Safe for humans and non-target organisms selective repeated applications possible Cons: May be slow Needs UV protection One week persistence Limited shelf-life May cause resistance if applied frequently PRODUCT: Foray® 48B – flowable concentrate (Valent BioSciences) Dose rate: 16-43 oz./acre Can be mixed with chemical insecticides

29. Neonicotinoids - related to nicotine and acts on the acetylcholine receptorsNeonicotinoids - related to nicotine and acts on the acetylcholine receptors –Imidacloprid most used worldwide –Clothinidin –Thiamethoxam –Acetamiprid –Dinotefuran* armored scales Safari® Other Types of Biorational Pesticides

30. Systemics for control of insect pests of trees and shrubs

31. IMIDACLOPRID Trade names ConfidorMeritAdmireGauchoMarathonPremierPremiseProvadoGrub-exImicide Bayer Advanced Garden Tree and Shrub Insect Control

32. IMIDACLOPRID Is it safe for non-target organisms? Moderate to low mammalian toxicityModerate to low mammalian toxicity Toxic to game birdsToxic to game birds But: birds learn to avoid it; may be used as bird repellent seed treatment Moderately toxic to fishModerately toxic to fish Highly toxic to aquatic invertebratesHighly toxic to aquatic invertebrates Highly toxic to honey bees if used as a foliar spray; not a hazard if used as a seed treatmentHighly toxic to honey bees if used as a foliar spray; not a hazard if used as a seed treatment

33. IMIDACLOPRID Very effective against pests with piercing-sucking mouthparts (aphids, soft scales, etc.) Easy to use: mix with water and pour at tree base Dose rate: 1 oz/inch of tree circumference or 3 oz/ft of shrub height Timing: apply in the fall for a year-long control 32 oz. - $18-$32

34. IMIDACLOPRID Problems May be phytotoxic – do not overdose!May be phytotoxic – do not overdose! May NOT work against armored scale insects or mitesMay NOT work against armored scale insects or mites Another neonicotinoid product - Safari® - works!Another neonicotinoid product - Safari® - works! Documented cases of resistance (Colorado potato beetle, whiteflies in greenhouses)Documented cases of resistance (Colorado potato beetle, whiteflies in greenhouses) Mobile in soil – potential water contaminantMobile in soil – potential water contaminant Extreme care is needed to protect honey beesExtreme care is needed to protect honey bees

35. Other new products?

36. FIPRONIL Combat® (cockroach and ant control) Regent® (agricultural pests) Frontline® (pet pests) Blocks GABA chloride channel in the insect CNS Both contact and stomach action, long residual Very effective at extremely low dose rates; insect trophic transfer; very low mammalian toxicity

37. Keeping up with changes* Crop Data Management Systems, Inc.Crop Data Management Systems, Inc. (they cover turf and ornamental products also) www.cdms.net GreenbookGreenbook www.greenbook.net *Also make sure your state approves of the federal label use (FIPRA). Some state labels are more strict than the federal

38. Quiz This guy is a Wyoming certified commercial pesticide applicator a. Trueb. False

39. Questions? Contact Alex Latchininsky or Scott Schell Phone 766-2298 or 766-2508 Email: latchini@uwyo.edu or sschell@uwyo.edu latchini@uwyo.edusschell@uwyo.edulatchini@uwyo.edusschell@uwyo.edu