Presentation on theme: "Since 1903 the VSVRI has been established on an area of about 23 square hectares in the Red Mountain area of the Abbassia district, east Cairo. The."— Presentation transcript:
Since 1903 the VSVRI has been established on an area of about 23 square hectares in the Red Mountain area of the Abbassia district, east Cairo. The VSVRI is one of the oldest and prestigious institutes in the Middle East and Africa. At the beginning, the scope of its responsibility was limited to production of vaccine and antiserum, for protection of cattle against Rinderpest (cattle plague).
The laboratory’s mission has continued to grow. The next period witnessed considerable laboratory expansions and new building constructions in response to the demands.
Production of highly efficient vaccines, Sera and Diagnostic Reagent utilizing both reference and local isolates based on the international standards to guarantee protection of animals and poultry from different diseases. In addition, preparation of combined vaccines to save the effort, time, stress and money. Conducting researches for improvement and innovation of Veterinary Vaccines, Sera and Diagnostic Reagents.
Completion of high Contemned BSl3 Laboratories for production of FMD & Avian Influenza Vaccines. Certified the current production facilities according to GMP requirements for veterinary vaccine production. Improvement and innovation of Veterinary Vaccines, Sera and Diagnostic Reagent. Using the molecular biology for improvement the vaccine and diagnostic reagents. Expanding training on up to date technologies. Completion of high Containment BSL-3 Laboratories for production of FMD & Avian Influenza Vaccines. Certified the current production facilities according to GMP requirements for veterinary vaccine production. Improvement and innovation of Veterinary Vaccines, Sera and Diagnostic Reagent. Using the molecular biology for improvement the vaccine and diagnostic reagents. Expanding training on up to date technologies.
Aerobic Bacterial Vaccines Research Department. Anaerobic Bacterial Vaccines Research Department. Bacterial Sera and Antigens Research Department. Bacterial Diagnostic products Research Department. Parasitic Vaccines Research Department.
FMD Research Department. Rift Valley Fever Vaccine Department. Pox Vaccines Research Department. Rinderpest Vaccine Research Department. Rinderpest like diseases vaccine Research Department. Pet animal Vaccines Research Department. Equine Vaccines Research Department. Newcastle and other Viral Poultry Vaccines Department.
Senior Researchers Chief Researchers Researchers Research Assistants Assistant Researchers Consultants Total Research Team 218
US Naval American Medical Research Unit (NAMRU 3). Us Department of State Biosecurity Engagement Program Food and Ogriculture Organization (FAO). Offices of International Epizootic (OIE). World Health Organization ( WHO )
The First HPAI outbreak was announced on February The disease is now endemic. Vaccine started on March 2007 depending on importation of H 5 N 1 and H 5 N 2 inactivated Vaccines from different counters. The key to preventing human infections with AI is to control poultry outbreaks of AI. Developing of national laboratory for vaccine production to produce AI vaccine from local isolates is must.
Laboratory location. Wipe – clean surface. Heating, ventilation and air – conditioning (HVAC) System. Directional airflow and cascade negative pressure. Laboratory furniture and equipment. Laboratory rooms, size and orientation. Sample reception. Double door autoclave and decontamination Chamber for solid waste materials. Water supply and sewerage system. Electrical system.
Primary containment barriers is the barriers between agent and man. Gloves, gownt, masks Biosafety cabinet, Respiratory protection Vaccines & autoclaves
Walls Fences, Security Quarantine Tertiary containment barrier Secondary containment barrier is the barrier between agents and Environment to provide protection for individual outside the lab. Air tight rooms. Air handling. Air locks. Showers, laundry. Sewage treatment. Waste disposal. Sterilization. Equipment.
The potential threat of Avian flu and need for appropriate facilities to work with HPAI raise design issues of protection.
Compact area Blending & Filling & Capping Electric room Exit Washing W.C Kitchen Control Hall Inactivation Lab. Refrigerator Electricity room Ref. Dressing Room Electricity Room Dressing Room Ref. Pre Inoculation Incubator Compact area After Inoculation Incubator Doctors Office Closet Receiving egg Compact area Freez. Inoculation Lab. Harvestation Steril.
All personnel must met the institutional expectation in term of high containment practices
Training of all personnel entering a containment facility must be done and documented Training program specific to scientists needs and knowledge Training and evaluation should occur before personnel starts the job
- U.S National Academy of Sciences. - U.S Department of States Biosecurity Engagement Program. -Turkish Academy of Sciences