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ERYTHROPOEISIS HemocytoblastProerythroblast Erythroblast BasophilicPolychroma- tophilic Erythroblast Orthochroma- tophilic Erythroblast Nuclear Extrusion Reticulocyte RBC Pluripotential Stem Cell 1. dispersed chromatin 2. nucleoli 3. cytoplasmic 1. clumped chromatin 2. no nucleoli 3. maximum 1. condensed chromatin 2. grey-green cytoplasm (hemoglobin synthesis) 1. condensed eccentric nucleus 2. pink cytoplasm 1. anucleate 2. spherical 3. slight basophilia (free ribosomes)
Erythropoeisis- Several Stages
MYELOPOEISIS (granulopoeisis) Hemocytoblast (multipotential) Myeloblast (multipotential) Promyelocyte (multipotential) 1. loss of cytoplasmic basophilia 2. dispersed chromatin EosinophilopoeisisNeutrophilopoeisisBasophilopoeisis
EOSINOPHILOPOEISIS Eosinophilic Myelocyte Eosinophilic Metamyelocyte Eosinophil (band cell) Specific and Metachromatic Granules
Eosinophilopoeisis- Several Stages
NEUTROPHILOPOEISIS NEUTROPHILIC MYELOCYTE NEUTROPHILIC METAMYELOCYTENEUTROPHIL
MYELOPOEISIS (Several Stages) Neutrophilic and Eosinophilic Band Cells Nutrophilic Band and Eosinophilic Metamyelocyte
BASOPHILOPOEISIS Basophilic Myelocyte Basophilic Metamyelocyte Basophil
THROMBOPOEISIS Hemocytoblast Endomytosis (w/o karyokinesis (w/o cytokinesis) Reserve Megakaryocyte (megakaryoblast)Platelet-Forming Megakaryocyte Platelet-Shedding (fusion of plasma membrane) Platelets Residual Megakaryocyte
BONE MARROW Decalcified Bone and Marrow Cavity Marrow Fat Cells Bone
Marrow Megakaryocyte Adipocyte Diapedesis Hemopoetic Compartment Endothelial Discontinuity Endothelial Cells Blood Sinusoid Reticular Fibers
Bone Marrow Bone Marrow in Decalcified Bone Bone Marrow Smear
B. Eosinophil Peripheral Blood Erythrocytes = RBCs NO NUCLEUS Contain hemoglobin.
1 Four Basic tissue types. 2 3 BLOOD -Blood is sometimes considered to be a fluid connective tissue because of the mesenchymal origin of its cells and.
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Course title: Hematology (1) Course code: MLHE-201 Supervisor: Prof. Dr Magda Sultan Date : 31 / 10/2013 Outcome : The student will understand : -The process.
Granulopoiesis Myeloblast Promyelocyte Myelocyte.
Cytomorphology of Normal Blood Cell Zhaoxindong
Hematopoiesis: Red Blood Cells Digital Laboratory It’s best to view this in Slide Show mode, especially for the quizzes. This module will take approximately.
Erythrocytes (RBC) Blood. Blood Smear with Erythrocytes – Red Blood Cells (RBCs)
Leukocytes Are mobile units of the body’s protective system Granulocytes a.Neutrophils b.Eosinophils c.Basophils Agranulocytes a.Monocytes b.Lymphocytes.
Hematopathology. This is the appearance of normal bone marrow at medium magnification. Note the presence of megakaryocytes, erythroid islands, and granulocytic.
ERYTHROPOIESIS. In adults, liver and spleen produce RBCs if bone marrow is destroyed or fibrosed. Bone marrow is equal to liver in size and weight. Involved.
Blood and Bone Marrow Learning Objectives 1.Be able to recognize all of the formed elements found in peripheral blood by light and electron microscopy.
Leukocytes Mobile units of body’s defence mechanism Granulocytes a.Neutrophils b.Eosinophils c.Basophils Agranulocytes a.Monocytes b.Lymphocytes.
Blood and haemopoiesis Lecture Blood Volume – approximately 5,5 L Hematocrit – volume of the erythrocyte mass: women 35 – 45%, men 40 – 50% Buffy.
Blood cells go through several stages of development; progression from one stage to the next is not rapid, so frequently the cell being studied may be.
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White blood cells Platelets Red blood cells Artery.
REVISION. يمكن الاستفادة من هذا العرض التقديمي في مراجعة ما يتعلق ب WBCs maturation & Leukemia هذا الجزء لا يشمل RBCs يمكن المراجعة ذاتيا عن طريق الضغط.
Chapter 17: Blood. William Harvey Discovered the nature of blood and circulation with the heart.
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