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Pediatric OTCs Carolyn Whiskin, BScPhm. Disclosure Honoraria have been received from the following companies in preparing, reviewing and giving presentations:

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Presentation on theme: "Pediatric OTCs Carolyn Whiskin, BScPhm. Disclosure Honoraria have been received from the following companies in preparing, reviewing and giving presentations:"— Presentation transcript:

1 Pediatric OTCs Carolyn Whiskin, BScPhm

2 Disclosure Honoraria have been received from the following companies in preparing, reviewing and giving presentations: PfizerAbbottMerckGlaxoSmithKline

3 Objectives To understand the Canadian Paediatric Society Guidelines regarding cough, cold and feverTo understand the Canadian Paediatric Society Guidelines regarding cough, cold and fever To understand treatment options and supportive measures for these conditionsTo understand treatment options and supportive measures for these conditions To be able to integrate homeopathic and traditional medication in pediatricsTo be able to integrate homeopathic and traditional medication in pediatrics

4 The Common Cold Young children have lowered immunity to the more than 100 different cold virusesYoung children have lowered immunity to the more than 100 different cold viruses Not uncommon to get as many as 8–10 colds/yr before age 2Not uncommon to get as many as 8–10 colds/yr before age 2 Fewer colds with age as exposure increases and immunity developsFewer colds with age as exposure increases and immunity develops Typical symptoms: runny/stuffed-up nose, sneezing, coughing,headache, mild sore throat, loss of appetite, fatigue, mild feverTypical symptoms: runny/stuffed-up nose, sneezing, coughing,headache, mild sore throat, loss of appetite, fatigue, mild fever

5 When To Refer Babies younger than 3 months having trouble breathing having trouble breathing not eating, or if they are vomiting not eating, or if they are vomiting have a fever (rectal temperature of 38.5°C or higher) have a fever (rectal temperature of 38.5°C or higher)

6 When to Refer Children of all ages Breathing rapidly or seem to be working hard to breathe Breathing rapidly or seem to be working hard to breathe Blue lips Blue lips Coughing causing choking or vomiting Coughing causing choking or vomiting Waking with one or both eyes stuck shut with dried yellow pus Waking with one or both eyes stuck shut with dried yellow pus

7 When to Refer Much more sleepy than usual, doesn’t want to feed or play, or is very fussy and cannot be comforted Much more sleepy than usual, doesn’t want to feed or play, or is very fussy and cannot be comforted Thick or coloured (yellow, green) discharge from the nose for more than 10 to 14 days. Thick or coloured (yellow, green) discharge from the nose for more than 10 to 14 days. Any sign of a middle ear infection (ear pain, drainage from the ear) Any sign of a middle ear infection (ear pain, drainage from the ear)

8 Spreading a Cold Viruses live in the nose, mouth, eyes and skin and can stay on surfaces for many hours Germs can spread whenever we touch one of these things and then touch our nose, mouth or eyes before washing our hands

9 Hand Washing Hand washing 15 to 20 seconds with warm water and soap for the time it takes to sing “Happy Birthday” twice 15 to 20 seconds with warm water and soap for the time it takes to sing “Happy Birthday” twice Avoid kissing, touching or holding hands Avoid kissing, touching or holding hands Elbow cover cough – droplets spread several feet Elbow cover cough – droplets spread several feet

10 Pertussis Prevention Also known as whooping coughAlso known as whooping cough 25 infant deaths in the USA in 2010 – majority spread from adults25 infant deaths in the USA in 2010 – majority spread from adults Adults age 19–65 require a Tdap boosterAdults age 19–65 require a Tdap booster Adults over 65 require a booster if they will be in close contact with an infantAdults over 65 require a booster if they will be in close contact with an infant Pregnant woman not already vaccinated should receive a booster in the late 2 nd semester or 3 rd trimesterPregnant woman not already vaccinated should receive a booster in the late 2 nd semester or 3 rd trimester

11 Cough and Cold Health Canada Guidelines Health Canada Guidelines As of the fall of 2009 all products containing traditional antihistamines, antitussives, expectorants and decongestants are to be labelled “Not for use under age 6”As of the fall of 2009 all products containing traditional antihistamines, antitussives, expectorants and decongestants are to be labelled “Not for use under age 6” Why the restriction?Why the restriction? Lack of evidence for these products in this age groupLack of evidence for these products in this age group Reports of misuse, overdose and adverse effects which include the following: increased heart rate, convulsions, decreased level of consciousness, abnormal heart rhythms and hallucinationsReports of misuse, overdose and adverse effects which include the following: increased heart rate, convulsions, decreased level of consciousness, abnormal heart rhythms and hallucinations

12 Why Restrictions? Body weight : children aged 2-6 can weigh the same as children under age 2 in whom these medications have not been indicated Body weight : children aged 2-6 can weigh the same as children under age 2 in whom these medications have not been indicated Increased exposure due to higher incidence of coughs and colds in this age group Increased exposure due to higher incidence of coughs and colds in this age group Children less likely to communicate adverse effects from these medications to caregiversChildren less likely to communicate adverse effects from these medications to caregivers

13 Standard Treatment Measures Health Canada feels that most colds resolve in 6-10 days and that there is no “cure” for the common cold Pharmacists can feel comfortable suggesting the following: Clear nasal passages and ensure that the child gets enough restClear nasal passages and ensure that the child gets enough rest Ensure the child gets plenty of clear fluids (e.g., diluted non- sweetened fruit juice, or clear soups)—this prevents dehydration, reduces congestion and keeps the throat moistEnsure the child gets plenty of clear fluids (e.g., diluted non- sweetened fruit juice, or clear soups)—this prevents dehydration, reduces congestion and keeps the throat moist Provide a comfortable environment with enough humidityProvide a comfortable environment with enough humidity

14 Which Humidifier To Use? Safety -Cool mist preferred to avoid burns Safety -Cool mist preferred to avoid burns Effectiveness Warm-mist and cool-mist humidifiers are equally effective. When water vapor reaches the lower airways, the temperature is the same. Aim away from bed and sheets. Effectiveness Warm-mist and cool-mist humidifiers are equally effective. When water vapor reaches the lower airways, the temperature is the same. Aim away from bed and sheets. Cost Cool-mist humidifiers are less expensive than are warm-mist Cost Cool-mist humidifiers are less expensive than are warm-mist Cleaning clean to prevent the growth of bacteria and molds. Wiping down the humidifier daily with a 10 percent bleach solution — 9 parts water to 1 part bleach — is one way to safely keep it clean Cleaning clean to prevent the growth of bacteria and molds. Wiping down the humidifier daily with a 10 percent bleach solution — 9 parts water to 1 part bleach — is one way to safely keep it clean Humidifiers add moisture to the air, which helps ease coughing and congestion due to a cold

15 Clearing Nasal Passages Suction with rubber bulb Suction with rubber bulb Squeeze the bulb syringe to expel air Squeeze the bulb syringe to expel air Insert the tip of the bulb about 1/4 to 1/2 inch (0.64 to 1.27 centimeters) into baby's nostril, pointing toward the back and side of the nose Insert the tip of the bulb about 1/4 to 1/2 inch (0.64 to 1.27 centimeters) into baby's nostril, pointing toward the back and side of the nose Release the bulb, holding it in place while it suctions the mucus Release the bulb, holding it in place while it suctions the mucus Remove the syringe and empty the contents onto a tissue by squeezing the bulb rapidly while holding the tip down. Remove the syringe and empty the contents onto a tissue by squeezing the bulb rapidly while holding the tip down. Clean the bulb syringe with soap and water Clean the bulb syringe with soap and water =lifestyle-and-home-remedies

16 Nasal Aspiration First may use saline solution to dilute secretionsFirst may use saline solution to dilute secretions Wash device with warm waterWash device with warm water Insert filterInsert filter Insert bulb into nostril while placing mouthpiece in caregiver’s mouth for inhalationInsert bulb into nostril while placing mouthpiece in caregiver’s mouth for inhalation Remove filter and clean deviceRemove filter and clean device

17 Saline Solutions  Benefits of rinsing: flushes out thickened mucus and irritants, may help ease swelling in the lining of nasal passages  Irrigation solution preparation: dissolve 1/8 teaspoon of table salt into 8 ounces of warm water  Commercially available products use sodium chloride 0.9%; sea salt based products use a deiozinizing process to bring to isotonic while leaving natural minerals

18 Homeopathy: View of the CPS Canadian Paediatric Society reviewed PubMed, CAM on PubMed, the Cochrane Library and Health Canada’s websites.Canadian Paediatric Society reviewed PubMed, CAM on PubMed, the Cochrane Library and Health Canada’s websites. No trials analyzing the effects of over-the-counter pediatric homeopathic preparations were found.No trials analyzing the effects of over-the-counter pediatric homeopathic preparations were found. There are only a few good studies showing possible benefits of homeopathy when prescribed by trained practitioners for a selected number of specific conditions in children.There are only a few good studies showing possible benefits of homeopathy when prescribed by trained practitioners for a selected number of specific conditions in children. Therefore, more rigorous studies showing efficacy need to be completed before it can be recommended as a credible complementary or alternative therapy for the pediatric population.Therefore, more rigorous studies showing efficacy need to be completed before it can be recommended as a credible complementary or alternative therapy for the pediatric population.

19 Homeopathy: View of the College of Family Physicians of Canada “It is important to keep in mind that, when used appropriately, natural health products can be a key part of a person’s health management.”“It is important to keep in mind that, when used appropriately, natural health products can be a key part of a person’s health management.” “Consumers can identify a Health Canada authorized natural health product by the eight-digit Natural Product Number (NPN) or Drug Identification Number for Homeopathic Medicine (DIN-4HM) on the label. These products are also required to have clear labeling on appropriate use, including dosing, risk information and whether they can be used safely in children.”“Consumers can identify a Health Canada authorized natural health product by the eight-digit Natural Product Number (NPN) or Drug Identification Number for Homeopathic Medicine (DIN-4HM) on the label. These products are also required to have clear labeling on appropriate use, including dosing, risk information and whether they can be used safely in children.” and cold medications frequently asked questions

20 More Comments 1997, by K. Linde et al. (Munich University) published meta-analysis of 135 clinical trials which compared homeopathic drugs with a placebo concluded that1997, by K. Linde et al. (Munich University) published meta-analysis of 135 clinical trials which compared homeopathic drugs with a placebo concluded that "the results of this meta-analysis are not compatible with the hypothesis that the clinical effects of homeopathy are completely due to placebo." 1997, by K. Linde et al. (Munich University

21 Natural Health Product Options Coryzalia Approved from one month – 6 years of ageApproved from one month – 6 years of age Indications: nasal congestion, runny nose and sneezingIndications: nasal congestion, runny nose and sneezing Dose: unit dose liquid vial t.i.d. for 5 daysDose: unit dose liquid vial t.i.d. for 5 days

22 Euphorbium Open, multicenter, prospective, active-controlled cohort study in patients with inflammatory processes and diseases of the upper respiratory tract.The primary outcome was to demonstrate non-inferiority of the homeopathic complex remedy to xylometazoline.Open, multicenter, prospective, active-controlled cohort study in patients with inflammatory processes and diseases of the upper respiratory tract.The primary outcome was to demonstrate non-inferiority of the homeopathic complex remedy to xylometazoline. Results: comparable efficacy and tolerability profile of Euphorbium compositum nasal drops SN and xylometazoline in patients with inflammatory processes and diseases of the upper respiratory tract (rhinitis/sinusitis).Results: comparable efficacy and tolerability profile of Euphorbium compositum nasal drops SN and xylometazoline in patients with inflammatory processes and diseases of the upper respiratory tract (rhinitis/sinusitis).

23 Euphorbium In vitro study using virus plaque reduction assays examined the effect of Euphorbium compositum SN against pathogens causing various viral infections: influenza A virus, respiratory syncytial virus (RSV), human rhinovirus (HRV) and herpes simplex virus type 1 (HSV-1).In vitro study using virus plaque reduction assays examined the effect of Euphorbium compositum SN against pathogens causing various viral infections: influenza A virus, respiratory syncytial virus (RSV), human rhinovirus (HRV) and herpes simplex virus type 1 (HSV-1). Euphorbium showed antiviral activity of against RSV and HSV-1. In addition, an antiviral effect against influenza A virus and HRV.Euphorbium showed antiviral activity of against RSV and HSV-1. In addition, an antiviral effect against influenza A virus and HRV.

24 Euphorbium Dose Nasal Spray: Age 2 to 12 years,1 spray into each nostril 3 times a day Nasal Spray: Age 2 to 12 years,1 spray into each nostril 3 times a day Oral Drops: Age 2-6, 5 drops 3x/day Age 6-12, 7 drops 3x/day Oral Drops: Age 2-6, 5 drops 3x/day Age 6-12, 7 drops 3x/day Acute Dosage: May use drops every minutes up to 12x/d Acute Dosage: May use drops every minutes up to 12x/d

25 Natural Health Products Viburcol Indicated for infants and children for: teething, pain, colic, infections with or without fever, sleeplessness and restlessnessIndicated for infants and children for: teething, pain, colic, infections with or without fever, sleeplessness and restlessness Dose: Age 0-2, 5 drops 3 x/day Age 2-6, 8 drops Age 6-12, 10 drops Acute – every minutes Dose: Age 0-2, 5 drops 3 x/day Age 2-6, 8 drops Age 6-12, 10 drops Acute – every minutes Suppository: 1 b.i.d. – 0-12 yrs Acute use every 1-2 hours

26 Viburcol Nonrandomized observational study of 38 Belgian centers practising homeopathy and conventional medicine Children <12 years old comparable to acetaminophen for poor eating, cramps, distress, sleep, crying and temperature Children <12 years old comparable to acetaminophen for poor eating, cramps, distress, sleep, crying and temperature

27 Cough An RCT with 139 children (24 to 60 mo) suffering from cough due to upper respiratory tract infection reported that 2.5 mL of honey before sleep improved cough frequency and severity, as well as sleep quality in a mean of 59% of childrenAn RCT with 139 children (24 to 60 mo) suffering from cough due to upper respiratory tract infection reported that 2.5 mL of honey before sleep improved cough frequency and severity, as well as sleep quality in a mean of 59% of children Honey was significantly superior to no treatment or honey-flavoured DM cough frequency and severity, bothersome nature of the cough, and the child/parent sleep quality, as rated by the parents Honey was significantly superior to no treatment or honey-flavoured DM cough frequency and severity, bothersome nature of the cough, and the child/parent sleep quality, as rated by the parents

28 Honey in Infants Younger Than 1 Year Only food linked to infant botulism Only food linked to infant botulism Infant botulism is caused by bacteria called Clostridium botulinumInfant botulism is caused by bacteria called Clostridium botulinum If honey is contaminated:If honey is contaminated: spores toxins paralysis spores toxins paralysis Bacteria and toxins are odourless, colourless, tasteless and not destroyed by cookingBacteria and toxins are odourless, colourless, tasteless and not destroyed by cooking Health Canada is advising parents and caregivers not to feed honey to children younger than 1 year of age

29 Fever Normal temperature ranges MethodNormal temperature range Rectal36.6°C to 38°C (97.9°F to 100.4°F) Rectal36.6°C to 38°C (97.9°F to 100.4°F) Ear 35.8°C to 38°C (96.4°F to 100.4°F)Ear 35.8°C to 38°C (96.4°F to 100.4°F) Oral 35.5°C to 37.5°C (95.9°F to 99.5°F)Oral 35.5°C to 37.5°C (95.9°F to 99.5°F) Axillary34.7°C to 37.3°C (94.5°F to 99.1°F)Axillary34.7°C to 37.3°C (94.5°F to 99.1°F)

30 Measurement Methods Summary of recommended temperature measurement techniques Age Recommended technique Birth to 2 years 1. Rectal (definitive) 2. Axillary (screening low risk children)Birth to 2 years 1. Rectal (definitive) 2. Axillary (screening low risk children) 2 to 5 years1. Rectal (definitive) 2. Axillary, Tympanic (or Temporal Artery if in hospital) (screening)2 to 5 years1. Rectal (definitive) 2. Axillary, Tympanic (or Temporal Artery if in hospital) (screening) Older than 5 years1. Oral (definitive) 2. Axillary, Tympanic (or Temporal Artery if in hospital) (screening)Older than 5 years1. Oral (definitive) 2. Axillary, Tympanic (or Temporal Artery if in hospital) (screening) Canadian Task Force on Preventive Health - Strength of Recommendation B, II [39] Canadian Task Force on Preventive Health - Strength of Recommendation B, II [39]

31 Oral Measures temperature of lingual arteriesMeasures temperature of lingual arteries Influenced by food/drink and oral breathingInfluenced by food/drink and oral breathing Relies of mouth sealed and tongue depressed for 3-4 minutesRelies of mouth sealed and tongue depressed for 3-4 minutes Mercury thermometers are no longer recommendedMercury thermometers are no longer recommended

32 Rectal Gold standard measurementGold standard measurement Slower to change based on core temperature changesSlower to change based on core temperature changes Affected by insertion depth and stool presenceAffected by insertion depth and stool presence Rectal perforation rare occurance- caution in neonates (1 in 2 million measurements)Rectal perforation rare occurance- caution in neonates (1 in 2 million measurements) Cleaning needed to prevent spread of fecal contaminantsCleaning needed to prevent spread of fecal contaminants

33 Axillary Inaccurate estimate of core temperature in childrenInaccurate estimate of core temperature in children Exact placement over axillary artery requiredExact placement over axillary artery required Environmental influencesEnvironmental influences Suggested as a screening in neonates by the American Pediatric SocietySuggested as a screening in neonates by the American Pediatric Society

34 Tympanic Measures thermal radiation emitted from the tympanic membraneMeasures thermal radiation emitted from the tympanic membrane Crying, otitis media and wax do not affect readingsCrying, otitis media and wax do not affect readings Ideal location for core temp. determinationIdeal location for core temp. determination Instrument design, depth of insertion and shape of ear canal can all cause variationsInstrument design, depth of insertion and shape of ear canal can all cause variations Size of device may affect accuracy in children under 2 yearsSize of device may affect accuracy in children under 2 years

35 When to Treat Fever is a sign that the body is working to fight infection – should not be fearedFever is a sign that the body is working to fight infection – should not be feared Fever has a purpose and may resolve viral infections soonerFever has a purpose and may resolve viral infections sooner Treatment mainly to provide comfort and reduce parent anxietyTreatment mainly to provide comfort and reduce parent anxiety Do not wake a sleeping child to give them a fever reducerDo not wake a sleeping child to give them a fever reducer Hydration and watching behavioural change emphasizedHydration and watching behavioural change emphasized No evidence fever reduction reduces morbidity and mortality or decreases the recurrance of febrile seizuresNo evidence fever reduction reduces morbidity and mortality or decreases the recurrance of febrile seizures

36 When To Refer Child with fever is less than 6 months old Child with fever is less than 6 months old Fever for longer than than 72 hours Fever for longer than than 72 hours Child is excessively cranky, fussy or irritable Child is excessively cranky, fussy or irritable Child is excessively sleepy, lethargic or does not respond Child is excessively sleepy, lethargic or does not respond Child is persistently wheezing or coughing Child is persistently wheezing or coughing Fever accompanies rash or any other signs of illness that are concerning Fever accompanies rash or any other signs of illness that are concerning

37 Treatment Choices Acetaminophen Dose: mg/kg per dose q4-6hDose: mg/kg per dose q4-6h No proof that a loading dose of 30 mg/kg works betterNo proof that a loading dose of 30 mg/kg works better Onset of Action: minutesOnset of Action: minutes Risk of hepatotoxity with doses over 15mg/kg or at intervals less than 4 hoursRisk of hepatotoxity with doses over 15mg/kg or at intervals less than 4 hours Combination treatment may offer slight benefitCombination treatment may offer slight benefit

38 Treatment Choice Ibuprofen Dose: 10mg/kg/ dose every 6-8 hoursDose: 10mg/kg/ dose every 6-8 hours Does not worsen asthma symptomsDoes not worsen asthma symptoms Can cause gastritis, bleeding and ulcers- less common in acute illnessCan cause gastritis, bleeding and ulcers- less common in acute illness Nephrotoxicity – renal insufficiency can develop; concern in dehydration where prostaglandin synthesis needed for renal blood flow.- caution in cardiac and renal patientsNephrotoxicity – renal insufficiency can develop; concern in dehydration where prostaglandin synthesis needed for renal blood flow.- caution in cardiac and renal patients Not to be used in infants younger than 6 monthsNot to be used in infants younger than 6 months

39 American Academy of Pediatrics Variable Acetaminophen Ibuprofen Decline in temperature, °C 1–2 1–2Decline in temperature, °C 1–2 1–2 Time to onset, h <1 <1Time to onset, h <1 <1 Time to peak effect, h3–4 3–4Time to peak effect, h3–4 3–4 Duration of effect, h4–6 6–8Duration of effect, h4–6 6–8 Dose, mg/kg 10–15 every 4 h 10 every 6 hDose, mg/kg 10–15 every 4 h 10 every 6 h Maximum daily dose, mg/kg90 mg/kg 40 mg/kgMaximum daily dose, mg/kg90 mg/kg 40 mg/kg Maximum daily adult dose, g/d4 2.4Maximum daily adult dose, g/d4 2.4 Lower age limit, mo 3 6Lower age limit, mo 3 6

40 Combination Treatment Studies indicate combination therapy may be more effective in reducing feverStudies indicate combination therapy may be more effective in reducing fever May not improve discomfortMay not improve discomfort Caution safety of combination treatmentCaution safety of combination treatment Dosage confusion can lead to overdoseDosage confusion can lead to overdose Generally not recommendedGenerally not recommended

41 Fighting the Virus Oscillococcinum RCT showed benefit over placebo in complete resolution or clear improvement in 48 hours (48% vs 63%)RCT showed benefit over placebo in complete resolution or clear improvement in 48 hours (48% vs 63%) Give one unit dose tube of pellets every 6 hours for 3 doses at the onset of symptoms. Ages 2 y and up (separate from food/toothpaste)Give one unit dose tube of pellets every 6 hours for 3 doses at the onset of symptoms. Ages 2 y and up (separate from food/toothpaste) Papp R, Schuback G, Beck E, et al. Oscillococcinum in patients with influenza-like syndromes: a placebo-controlled, double-blind evaluation. Br Homeopath J 1998;87:69-76

42 Fighting the Virus Sambucol In an RCT – reduced flu symptoms to 3-4 days; influenza antibodies increased and TNF-alpha production increased (44.9 fold)In an RCT – reduced flu symptoms to 3-4 days; influenza antibodies increased and TNF-alpha production increased (44.9 fold) Study concluded that, in addition to its antiviral properties, Sambucol Elderberry Extract and its formulations activate the healthy immune systemStudy concluded that, in addition to its antiviral properties, Sambucol Elderberry Extract and its formulations activate the healthy immune system The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines

43 Sambucol Daily maintenance Children 1-6 years of age: take 1 teaspoon (5 mL) daily Children 7-12 years of age: take 2 teaspoons (10 mL) daily Intensive use Children 1-6 years of age: take 1-2 teaspoons (5-10 mL) twice daily Children 7-12 years of age: take 2-3 teaspoons (10-15 mL) twice daily Children 7-12 years of age: take 2-3 teaspoons (10-15 mL) twice daily

44 Fighting the Virus Engystol RCT and observational studies show comparable results to acetaminophen in reducing symptoms and phagocytic activity improvedRCT and observational studies show comparable results to acetaminophen in reducing symptoms and phagocytic activity improved Children (6 to 12 years) 1 tablet 2 times daily. In acute cases, 1 tablet every 1 to 2 hours, up to 8 times a day Children (6 to 12 years) 1 tablet 2 times daily. In acute cases, 1 tablet every 1 to 2 hours, up to 8 times a day Young children (2 to 6 years) ½ tablet 3 times daily. In acute cases, 1 tablet every 1 to 2 hours, up to 6 times a day Young children (2 to 6 years) ½ tablet 3 times daily. In acute cases, 1 tablet every 1 to 2 hours, up to 6 times a day Babies (0 to 2 years) ½ tablet 2 times daily. In acute cases, 1 tablet every 1 to 2 hours, up to 4 times a day Babies (0 to 2 years) ½ tablet 2 times daily. In acute cases, 1 tablet every 1 to 2 hours, up to 4 times a day Dissolve slowly in the mouth or in a teaspoon of water before administering to a young child or baby Dissolve slowly in the mouth or in a teaspoon of water before administering to a young child or baby

45 Other Options Echinacea 2006 Cochrane review identified 16 controlled trials on the effect of echinacea for cough—no sufficient data to suggest the effectiveness of echinacea in children. The use of echinacea for eight to 12 weeks as a prophylactic measure did not result in effective prevention of the common cold (Source: CPS)2006 Cochrane review identified 16 controlled trials on the effect of echinacea for cough—no sufficient data to suggest the effectiveness of echinacea in children. The use of echinacea for eight to 12 weeks as a prophylactic measure did not result in effective prevention of the common cold (Source: CPS)

46 Other Options Zinc Some studies showed benefits, especially if used within 24 h of the onset of common cold symptomsSome studies showed benefits, especially if used within 24 h of the onset of common cold symptoms Other studies showed no benefitOther studies showed no benefit At the present time, the use of zinc in children with cough and cold is not recommended (Source: CPS)At the present time, the use of zinc in children with cough and cold is not recommended (Source: CPS)

47 Vaccinations Use of anti-pyretics before vaccination may reduce the immune responseUse of anti-pyretics before vaccination may reduce the immune response Sugar water preferred to reduce discomfort before vaccination Sugar water preferred to reduce discomfort before vaccination To make sugar water, mix one packet of sugar (1 teaspoon) with 10 ml of water (2 teaspoons). Administer with a cup, spoon or syringe just before the needle and discard the unused portionTo make sugar water, mix one packet of sugar (1 teaspoon) with 10 ml of water (2 teaspoons). Administer with a cup, spoon or syringe just before the needle and discard the unused portion

48 Making a Difference Providing information to parents regarding the care of their sick child is a vital service pharmacists provide to the community Take the time to share your knowledge We all benefit!!


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