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The CombiFlash® Rf 150 Preparative Performance at a fraction of the cost Teledyne Isco Confidential.

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Presentation on theme: "The CombiFlash® Rf 150 Preparative Performance at a fraction of the cost Teledyne Isco Confidential."— Presentation transcript:

1 The CombiFlash® Rf 150 Preparative Performance at a fraction of the cost Teledyne Isco Confidential

2 CombiFlash Rf 150 Features ■ Flow rate up to 100 mL/min ■ Pressures up to 150 psi (10.3 bar) ■ Binary Gradient ■ Two solvent selectivity ■ Uses standard Rf racks ■ Ceramic piston with no check valves for maintenance free operation ■ Low pressure mixing ■ Gradient accuracy typically 2% of full scale ■ Variable UV or UV-Vis detection options ■ Uses PeakTrak® control software ■ November Software release will add Spectral capabilities to Rf 150 Teledyne Isco Confidential

3 Optimized for Reversed Phase Purifications ■ Reversed phase purifications often operate at pressures between 75 psi and 100 psi ■ Designed to run at maximum flow rate up to 150 psi ■ Available with either a variable UV or UV-Vis detector ■ Driven by PeakTrak® Teledyne Isco Confidential

4 Market Focus for Rf 150 ■ Aimed at Academic Market ■ Heavy discounting is needed to win business ■ May not use RediSep® Rf columns ■ Infrequent usage accounts ■ Financially underfunded accounts Teledyne Isco Confidential

5 Rf 150 Product Promotions ■ Direct Mail Piece to Academic accounts ■ ACS Members who are Post Doctorial Fellows (5,000) ■ blast to University names from R&D List ■ blast to University names in Tisco List Teledyne Isco Confidential

6 Direct Mailer Teledyne Isco Confidential 6

7 Rf 200 versus Rf 150 Rf 200 ■RFID rack identification ■RFID rack detection ■RFID column detection ■Supports column plan ■External detector port ■Solvent level sensing ■Injection valve ■Air purge ■Four solvents to select from ■Higher pressure and flow rate limits Rf 150 ■No rack identification ■No rack detection ■No external detector ■DOES NOT SUPPORT COLUMN PLAN ■No air purge ■Two solvents to choose from ■Lower pressure and flow rate ■No level sensing ■No injection valve Teledyne Isco Confidential

8 Competition Biotage Isolera Prime CombiFlash Rf 150 Isolera Prime Pumping System Ceramic no-check valve pump Constant Volume Electric Pump Flow Range mL/min mL/min Pressure Limit 150 psi (10.3 bar) 145 psi (10 bar) Detection Variable UV nm standard Variable UV-Vis nm option Fxed UV 254nm standard Variable UV nm option Number of Solvents Two, binary gradient Programmable Gradients Linear, step, isocratic Gradient Accuracy Typically <2% Not Stated Sample Injection Direct User Interface 10.5" touchscreen 10.4" touchscreen Software PeakTrak Proprietary Fraction Collector Internal Dimensions 24" H x 14.1" W x 17" D 23.5" H x 14" W x 19.6" D Column Sizes 4 to 330 Gram Not Stated Weight 66 lbs. Certifications CE CE, cTUVus Biotage US List Price of $17,500 Teledyne Isco Confidential

9 Competition - Agela Cheetah Agela US List Price Unknown – Sold through VWR CombiFlash Rf 150Agela Cheetah MP 100 Pumping System Valveless ceramic metering pump Flow Range mL/min mL/min Pressure Limit 150 psi (10.3 bar)100 psi Detection Variable UV nm standard Variable UV-Vis nm option Variable UV nm standard Variable UV-Vis nm option Number of SolventsTwo, binary gradient Two, binary gradient standard Quaternary gradient option Programmable Gradients Linear, step, isocratic Gradient Accuracy Typically <2% Not Stated Sample Injection Direct Direct Injection valve option User Interface 10.5" touchscreen 12.1" touchscreen Software PeakTrak Proprietary Fraction Collector Internal Dimensions 24" H x 14.1" W x 17" D Not Stated Column Sizes 4 to 330 Gram Not Stated Weight Not Stated Certifications CE Not Stated Teledyne Isco Confidential

10 Competition – Lisure Science CombiFlash Rf 150Lisure Science EZ Purifer Pumping SystemValveless ceramic metering pump Flow Range mL/min mL/min Pressure Limit150 psi (10.3 bar)100 psi (7 bar) Detection Variable UV nm standard Variable UV-Vis nm option Variable UV-Vis nm Number of SolventsTwo, binary gradient Programmable GradientsLinear, step, isocratic Gradient AccuracyTypically <2%+/-3% linear gradient Sample InjectionDirect User Interface10.5" touchscreenPC SoftwarePeakTrakWindows Fraction CollectorInternal Dimensions24" H x 14.1" W x 17" DNot Stated Column Sizes4 to 330 GramNot Stated Weight Not Stated CertificationsCE Not Stated Lisure does not sell outside of India and China Teledyne Isco Confidential

11 Competition - Yamazen CombiFlash Rf 150Yamazen AI-580S Pumping SystemValveless ceramic metering pumpNot Stated Flow Range mL/min mL/min Pressure Limit150 psi (10.3 bar)145 psi Detection Variable UV nm standard Variable UV-Vis nm option Fixed UV 254 nm standard Variable UV nm Variable UV-Vis nm option Number of SolventsTwo, binary gradient Programmable GradientsLinear, step, isocratic Gradient AccuracyTypically <2%Not Stated Sample InjectionDirectNot Stated User Interface10.5" touchscreenTouch screen PC SoftwarePeakTrakWindows Fraction CollectorInternal Dimensions24" H x 14.1" W x 17" D30.7" H x 19.7" W x 17.7" D Column Sizes4 to 330 GramNot Stated Weight Not Stated CertificationsCEJIS, CE Yamazen US List Price $21,200 Teledyne Isco Confidential

12 Pricing UV$24, UV-Vis$25,004 Teledyne Isco Confidential

13 Key Markets Teledyne Isco Confidential 13


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