1. Medical Device Resources on Dialog & DataStar
Bonnie Snow
Director, Pharmaceutical Markets
Vendor Update
SLA Pharmaceutical & Health Technology Division
Toronto, June 2005

2. Answering medical device inquiries requires access to…
Biomedical bibliographic databases
Engineering literature
Regulatory resources
A highly focused collection of full-text industry newsletters
Subject specialty company & product directories
Market research sources (reports, statistics)
Intellectual property databases

3. Dialindex/OneSearch Category MEDDEV
File 2:INSPEC
File 5:Biosis Previews(R)
File 6:NTIS
File 8:Ei Compendex(R)
File 34:SciSearch(R) Cited Ref Sci
File 35:Dissertation Abs Online
File 65:Inside Conferences
File 73:EMBASE
File 74:Int.Pharm.Abs
File 92:IHS Intl.Stds.& Specs. 1999/Nov
File 94:JICST-EPlus
File 144:Pascal
File 155:MEDLINE(R)
File 158:DIOGENES(R)
File 172:EMBASE Alert 2005
File 182:FDA News Mar
File 188:Health Devices Sourcebook 2004
File 198:Health Devices Alerts(R)
File 399:CA SEARCH(R)
File 434:SciSearch(R) Cited Ref Sci
File 441:ESPICOM Pharm&Med DEVICE NEWS 2005
File 444:New England Journal of Med

4. Some Distinctions Among Major Biomedical Bibliographic Sources…
MEDLINE
Best coverage of dental literature among major biomedical bibliographic databases
Pertinent subheadings to identify references to Instrumentation (IS) and Methods (MT)
EMBASE
Generally considered to provide better coverage of selected subject specialty areas, including:
Biomedical engineering & instrumentation, medical devices
Ophthalmology
Plastic surgery
Pharmaceutics (PR) singled out as a LINK term, as are routes of drug administration – Important in isolating references to new drug delivery systems that include a device component
Quicker to adopt new vocabulary for use in controlled indexing, e.g., drug eluting stent added as controlled (thesaurus) term in June 2003
When primary source cites device brand name(s) and/or specific manufacturers, EMBASE includes names in online records (provides access to product-oriented literature, even when names have been omitted in the author’s original title and abstract)

5. Some Distinctions Among Major Biomedical Bibliographic Sources…
BIOSIS Previews
Broader subject coverage: all life sciences, including biophysics & bioengineering
Pertinent Major Concept indexing: “Biomedical Engineering”; “Equipment, Apparatus, Devices and Instrumentation”
Emphasis on research, rather than routine clinical practice or established procedures, making it a good source for searching medical technologies under development & preclinical literature
Provides access to additional resources not found in other “Big 4” files
Books, theses, reports, U.S. patents, proceedings of scientific symposia, conference papers & poster presentations at scientific meetings
SciSearch
Multi-disciplinary in scope, with coverage of 5,200 journals, provides access to a cross-section of literature that includes not only biomedical journals, but also engineering, mathematics, biophysics, and pharmaceutical technology resources
Cover-to-cover indexing not found elsewhere
Extremely timely; very short lag time
Natural language indexing reflects terminology changes, new concept vocabulary
Cited reference search capabilities

6. Complementary Resources
International Pharmaceutical Abstracts
Can contribute unique references to specialty journals in the pharmaceutics & pharmaceutical technology subject areas – helpful when focusing on new drug delivery technologies that involve a device component
CA Search
Another source for pharmaceutics-oriented literature. Also indexes conference proceedings & provides a selective gateway to the patent literature
JICST
Coverage of literature published in Japan, encompassing all fields of science, technology, and medicine. Indexing of 6,000 journals + conference papers, technical reports
PASCAL
Often yields additional references to scientific & technical literature, including conference papers

7. Engineering Literature Indexes
In the engineering literature, topical emphasis shifts to durability testing, mathematical analysis, materials science (preparation, characterization, manufacturing)
Database coverage of technical conference proceedings is a bonus
EI Compendex
Take advantage of hierarchical Classification Code indexing: Bioengineering codes under CC=46
CC= (BIOENGINEERING)
CC= (BIOMEDICAL ENGINEERING)
CC= (BIOLOGICAL MATERIALS)
CC= (BIOMECHANICS)
CC= (HUMAN ENGINEERING)
CC= (HUMAN REHABILITATION ENGINEERING)
CC= (MEDICINE)
CC= (HEALTH CARE)
CC= (BIOTECHNOLOGY)
CC= (GENETIC ENGINEERING)
CC= (BIOLOGY)
CC= (IMMUNOLOGY)
CC= (MEDICAL ENGINEERING & EQUIPMENT)
CC= (BIOMEDICAL EQUIPMENT, GENERAL)
CC= (HOSPITALS, EQUIPMENT & SUPPLIES)
CC= (DENTAL EQUIPMENT & SUPPLIES)
CC= (PROSTHETICS)
CC= (BIOMATERIALS)

8. Engineering Literature Indexes
INSPEC
Device related class codes under: CC=A87, CC=B75, e.g.:
CC=A8770 Biomedical engineering
CC=A8770E Patient diagnostic methods & instrumentation
CC=A8770F Electrodiagnostics
CC=A8770J Prosthetics & other practical applications
CC=A8780 Biophysical instrumentation & techniques
CC=A8780B Biosensors
CC=B7500 Medical physics & biomedical engineering
CC=B7510 Biomedical measurement & imaging
CC=B7510B Radiation & radioactivity applications in biomedicine
CC=B7510D Bioelectric signals
CC=B7520C Radiation therapy
CC=B7520E Prosthetics & orthotics
CC=B7530 Health Physics
CC=B7530B Radiation protection & dosimetry
CC=B7540 Hospital Engineering
plus…
CC=C1290L Systems theory applications in biology & medicine
CC=C Biological & medical control systems
CC=C3385C Prosthetic & orthotic control systems
CC=C Medical administration
CC=C Biology and medical computing
CC=D Health care applications

9. Engineering Literature Indexes
MEDITEC: Biomedical Engineering
BMED on DataStar, present, updated weekly
Compiled by FIZ Technik, the MEDITEC database contains citations, with abstracts, to the international literature on biomedical engineering. Information is compiled from journals, conference papers, books, technical reports, and dissertations. The primary language of the database is German, but many search terms and abstracts are also in English.
Topics covered include:
Biomedical measurements (recording, plotting, processing, and evaluation of physiological parameters)
Medical imaging (e.g., computed tomography, magnetic resonance imaging)
Data processing in medicine
Biomaterials and materials for medical instrumentation
Medical instruments for diagnostic and therapeutic applications
Prostheses and rehabilitation engineering
Clinical laboratory technology
Optometry and ophthalmological instruments
Dental technology
Clinical engineering, hospital management

10. Answering medical device inquiries requires access to…
Biomedical bibliographic databases
Engineering literature
Regulatory resources
A highly focused collection of full-text industry newsletters
Subject specialty company & product directories
Market research sources (reports, statistics)
Intellectual property databases

11. Regulatory Information Sources
DIOGENES FDA Regulatory Updates – File 158, DIOG (FOI Services)
Premarket Application (PMA) approvals & 510K notifications ( )
Access to DIOGENES on Dialog facilitates downloading of retrospective data for post-processing and analysis, e.g., easy export of XML data in EXCEL spreadsheet format via DialogLink 5
Product recalls ( )
More retrospective coverage than offered on FDA Web site ( )
FDA.GOV search capabilities for product recalls are extremely limited. The current search interface identifies only the co-occurrence of terms within entire issues of the FDA Enforcement Report, making it difficult to isolate pertinent data from individual recalls & resulting in many “false drops”
Enhanced accessibility to recall data through DIOGENES on Dialog
Easy to single out Class I, II, or III recalls for given companies in specified time periods
Dialog users of DIOGENES can also produce RANKed analyses of enforcement actions for comparisons/trend monitoring
Medical Device Reports (MDRs = adverse experience/incident reports), 1985 –
DIALOG RANK capabilities enable statistical analysis of MDRs, e.g., examination of a specified company’s product line by ranked incidence of adverse experience reports; review the “track record” of an entire device category & compare incidence of AEs associated with given companies

12. Regulatory Information Sources
Health Devices Alerts – File 198 (ECRI), updated weekly
Database compiles reports of problems with specified devices, plus references to published evaluations and technology assessments
MDRs ( )
Action Items – Most are related to recalls that ECRI has investigated or verified (1982 -)
Provide details not readily accessible elsewhere online, such as specific follow-up recommendations issued by manufacturers to avoid or remedy further problems with named devices
ECRI also often identifies errors or omissions in original FDA notices (e.g., incorrect serial #s of affected models)
Abstracts of articles from the published literature,
Brand & mfg name access to pertinent bibliography in primary medical literature, augmenting accessibility to same articles cited in EMBASE & MEDLINE
ECRI abstracts of source documents typically provide more detailed data than that included in the original author abstract reproduced in other bibliographic databases

13. Regulatory Information Sources
Regulatory Affairs Journal
PHRJ on DataStar, January 2003 – present
Forthcoming on Dialog
Worldwide regulatory intelligence, news, and informed commentary
Produced by T&F Informa UK Ltd (formerly PJB Publications), these full-text journals report on pertinent legislation, approval application requirements & guidelines, pharmacovigilance initiatives, and harmonisation, trade, and environmental issues with potential impact on drug regulation & marketing worldwide
RAJ Pharma, updated monthly, covers both human & veterinary drug regulatory developments
RAJ Devices, updated bimonthly, focuses on medical device & in vitro diagnostics

14. Extracts from RAJ Devices TOC – March/April 2005 issue

15. Examples of searchable data elements in the Regulatory Affairs Journal online
Country or region names
e.g., “UK” or “European Union”
Article type
e.g., “Worldwide update” “Reference-Guidelines” “Reference-Standards” “Organisational Charts”
Product sectors
Subject categories
Article title & full text, including…
Cited references
Useful when searching for discussion related to specific regulations, directives, or guidelines issued by government authorities
Keywords - Controlled descriptors identifying specific topics discussed in articles
Examples: “Environment” or “Counterfeit Medicines”

18. Regulatory Affairs Journal enhanced with Images on DataStarWeb platform
Example from RAJ - Devices

19. Regulatory Information Sources
EURALex
(formerly ERA News, EPLC Update) , , updated monthly
Complete text in PHIND (File , PHIN/PHIC)
Reports on European legal and regulatory affairs likely to affect the human and animal drug and device markets, including changes in the structure and organization of national healthcare systems, individual governments’ policies regarding pricing and reimbursement, control of clinical trials, intellectual property protection, advertising, competition and company law, etc.
Includes expert commentary & analysis of implications
Each issue typical covers..
New directives, regulations, and guidelines
Court cases & rulings
Developments at national, as well as European, level
Meetings

20. Regulatory Information Resources
CELEX - European Union Law (CLXE)
1951 – present, updated weekly
CELEX provides the full text and/or references for all European Community legislation and is the only interactive online database covering all EC law.
Coverage includes treaties and other agreements, preparatory legislative documents, parliamentary questions, and individual nation’s implementation measures.
CELEX can help answer such questions as:
Has the EC passed legislation on a particular topic?
Has this been amended?
Has the European Court of Justice ruled on it?
Has there been a question in the European Parliament on it?

21. Answering medical device inquiries requires access to…
Biomedical bibliographic databases
Engineering literature
Regulatory resources
A highly focused collection of full-text industry newsletters
Subject specialty company & product directories
Market research sources (reports, statistics)
Intellectual property databases

22. Among full-text subject specialty sources in PHIND…
Pharmaceutical & Healthcare Industry News Database (File , PHIN/PHIC) includes:
Clinica – World Medical Device & Diagnostics News
Legendary for its scope and timeliness, Clinica reports on a broad spectrum of scientific, political, regulatory, and financial news of vital interest to device industry personnel. Coverage includes informed commentary, critical evaluation of current events, and trend analysis.
Instrumenta
Current awareness source focusing on the analytical instrument and laboratory equipment industries
Target
Focuses on worldwide drug delivery technology & business developments, including products/platforms incorporating medical devices
Each of these titles is offered for TOC Alerts (automated current awareness & document delivery service -- see additional information in handout)

23. ALERT Capabilities on Dialog
Customized current awareness service for ongoing monitoring of new developments
User specifies keywords, other factors to be searched in each update to a database
New material matching user-defined parameters forwarded daily, weekly, biweekly, or monthly
Option for Multi-file Alert with duplicate detection
TOC (Table of Contents) Interactive Alerts
Full table-of-contents scans delivered to -box
User checks off titles for which full text needed
Full documents delivered within minutes by return
Copyright compliance incorporated into service

24. Dialog Interactive TOC Alerts
Current Dialog users can set up TOC Alerts by logging on to DialogWeb ( with their standard user # and password
Go to the opening screen in Command Mode.
Note: You need not be familiar with Dialog commands to set up an Interactive Alert
Click on Alerts in the Quick Functions box.

25. From the subsequent “Alerts” screen, click on Add Subscriptions

26. Use the pull-down Publications menu to select a newsletter title
After selecting a newsletter title, type in an address for the recipient (you, your client)
Tip: Prior to initiating the service, you may wish to arrange for creation of a special mailbox within your organization’s system, from which daily alerts will be disseminated internally to a designated distribution list. Each individual recipient will be able to order full-text documents directly, and Dialog will automatically aggregate multiple copy orders to calculate ERA discounts, when applicable.

27. Users simply check off items in their replies to order full-text articles (delivered within 2 hrs) at standard database output rates.
Note that this is a non-invasive “push” (current awareness) service. No response is necessary, if no items in a Table of Contents are of interest. Built-in “grace period”: each Interactive Alert ends with a “reply by” date (usually two weeks hence) for automated document delivery.

28. Other full-text newsletters of potential interest to device searchers…
ESPICOM Pharmaceutical & Medical Device News (File 441, MDNE) includes:
Cardiovascular Device Business
Drug Delivery Insight
Medical Imaging Business
FDA News (File 182) includes:
Devices & Diagnostics Letter (weekly)
FDANews Device Daily Bulletin
The GMP Letter (monthly)
Gale Group Newsletter Database (File 636) includes:
Biomedical Materials
Biotech Equipment Update
Hospital Materials Management
Medical Textiles

29. Answering medical device inquiries requires access to…
Biomedical bibliographic databases
Engineering literature
Regulatory resources
A highly focused collection of full-text industry newsletters
Subject specialty company & product directories
Market research sources (reports, statistics)
Intellectual property databases

30. Subject Specialty Company Directories
Health Devices Sourcebook (File 188), updated annually
Provides current address and marketing information for more than 6,000 North American (U.S. & Canadian) manufacturers, distributors, and service companies associated with any of more than 4,500 classes of products. Listings include sources for diagnostic and therapeutic devices and materials, including laboratory equipment and reagents, systems and instruments used to monitor and test equipment, and selected hospital furniture or supplies.
Manufacturer records typically include
name, address, telephone number, fax #, website URL, address
year started
parent company (when applicable)
# employees, # sales people
total annual sales
fiscal year (month-month range used)
names & titles of executive staff
plus product categories or classes produced and their brand names
Also identify whether publicly or privately owned, minority-owned, woman-owned, eligible for GSA and/VA contracts
Service company entries show category of service (e.g., maintenance, repairs, leases), geographical areas covered, and contact information.

31. Subject Specialty Company Directories
ESPICOM Pharmaceutical & Medical Company Profiles (File 510, MDCO)
Detailed reports on more than 200 ethical pharmaceutical, generics, and medical device companies worldwide
New profiles published annually, updated monthly as new information becomes available

32. Example of Major Section Headings in ESPICOM’s 2004 profile for Abbott
? RANK S1 SE;CONT;ALL
DIALOG RANK Results
RANK: S1/ Field: SE= File(s): 510
(Rank fields found in 108 records--8 unique terms) Page 1 of 1
RANK No. Items Term
PRODUCT PORTFOLIO
AGREEMENTS
RESEARCH AND DEVELOPMENT
RECENT HISTORY/CORPORATE STRATEGY
STRUCTURE AND ACTIVITIES
FINANCIAL INDICATORS
GEOGRAPHICAL BREAKDOWN
PROFILE OVERVIEW
---end of results---

33. Example of Major Section Headings in ESPICOM’s 2005 profile for Zimmer
RANK: S4/ Field: SE= File(s): 510
(Rank fields found in 61 records -- 8 unique terms) Page 1 of 1
RANK No. Items Term
PRODUCTS
CORPORATE HISTORY
FINANCIAL REVIEW
RESEARCH AND DEVELOPMENT
CORPORATE STRUCTURE
INTERNATIONAL ACTIVITIES
OVERVIEW
STRATEGIC FOCUS
---end of results---
Financial Review includes separate records tabulating revenue by geographic segment, by operating division, and by product category, as well as overall “financial indicators” data

34. Extract from a sample record…
DIALOG(R)File 510:ESPICOM Pharm & Med Co. Profile
(c) 2005 ESPICOM Bus. Int. All rts. reserv.
Main Title: Zimmer 2005 Medical Device Company
Pub. Date: FEBRUARY 2005
Source: Medical Device Companies Analysis
FISCAL 2004 (Part 4)
Sales of orthopaedic surgical products rose by 9% in 2004 based on
combined results for Zimmer and Centerpulse in 2003.
Table 3, Revenue by Product Category, (US$ million)*
% Change
2003/2004
Reconstructive , ,
Trauma
Spine
Orthopaedic Surgical Products
Total Revenue , ,

35. Answering medical device inquiries requires access to…
Biomedical bibliographic databases
Engineering literature
Regulatory resources
A highly focused collection of full-text industry newsletters
Subject specialty company & product directories
Market research sources (reports, statistics)
Intellectual property databases

36. Subject Specialty Product Directories
Drug Pipeline databases
DO cover products under development in formulations that use drug delivery technologies combining devices + drugs or biologics
Examples:
Drug-eluting stents
Surgical implants
Metered-dose inhalers

37. Pharmaprojects (File 128,928,PHAR)
Only pipeline file to enhance the EPhMRA therapeutic classification scheme with an entire category designed to improve indexing of formulations
Only file to have hierarchical indexing for routes of administration, as well
“Novelty” rating will help identify products involving new formulations
Sample application…
Drug-eluting stents are indexed with the TC code F9A (Formulation, Implant)
This code can also be used to locate products in other therapeutic areas under investigation for delivery via implantation

38. E5 1349 NR=1 (ALL PRECLINICAL) E6 1657 NR=2 (ESTABLISHED STRATEGY)
? S TC=F9A
S TC=F9A
? E NR=
Ref Items Index-term
E NA=99MTC-ECD
E NA=99MTC-5T4 MAB
E *NR=
E NR=0 (NOT AVAILABLE)
E NR=1 (ALL PRECLINICAL)
E NR=2 (ESTABLISHED STRATEGY)
E NR=3 (NEW FORMULATION)
E NR=4 (LOW NOVELTY)
E NR=5 (2ND, 3RD OR 4TH COMPOUND)
E NR=6 (LEADING COMPOUND)
? S E7
S NR='3' (NEW FORMULATION)
? S S1 AND S2
S S1 AND S2
F9A represents FORMULATION, IMPLANT
EXPAND for Novelty Rating options
 ? S S3 AND TC=K
S S3 AND TC=K
Focusing on anticancer products (K category)

39. IMS R&D Focus (File 445, 955, IPUR)
Indexing of drug-eluting stents
“Stent” may appear in the product Name ( /NA) or in the pharmacological action ( /AC) field
However, for stents still in early stage of development, keyword could appear in record text (/TX)
Recommendation: search “stent” without qualification to a specific field
Drug Name: drug delivery system, vascular stent sirolimus; sirolimus vascular stent
DRUG INFORMATION:
Pharmacological Action: antiproliferative agent; stent
Therapeutic Class Code: C1D (Coronary Therapy); V7A (All Other Non-Therapeutic Products)
Clinical Indications: restenosis

40. IMS R&D Focus Broader approaches to searching drug delivery
As was illustrated in the previous record extracts, “Drug Delivery System” may be identified in the product Name field ( /NA)
The phrase may also appear in the Substance Origin field
Recommendation: search the phrase without qualification to a specific field
Additional records can be located by searching…
“Delivery System” in the Indications field
“Drug Design Technology” in the /IN field
The keyword “Technology” in Status ( /ST) indexing

41. IMS R&D Focus Broader approaches to searching drug delivery
? DS
Set Items Description
S DRUG()DELIVERY()SYSTEM/PROFILE
S (DELIVERY()SYSTEM OR DRUG()DESIGN()TECHNOLOGY)/IN
S TECHNOLOGY/ST
S S2 OR S3
Locates additional records not identified with previous strategy.
/AVAIL limits results to products available for licensing.
? S S4 NOT S1
S S4 NOT S1
? S S5/AVAIL
S S5/AVAIL
Because many of these records lack specific Therapeutic (TC) or Indications indexing, search keywords for potential applications as “free text” (without field qualification).
? S S6 AND VACCINE?
S S6 AND VACCINE?
See sample record in handout

42. Extract from sample record
DIALOG(R)File 445:IMS R&D Focus
(c) 2004 IMS Health & Affiliates. All rts. reserv.
Drug Name: Powder Mediated Epidermal Delivery
Brand Name: PMED
R&D Focus - September 27, 2004 ( )
COMPANY INFORMATION:
Originator: PowderMed; (UK); NA; NA; NA
Licensing Countries: Worldwide
Licensing Contact: Brenda Reynolds, Chief Operating Officer,
PowderMed Ltd, 4 Robert Robinson Avenue, The
Oxford Science Park, Oxford, OX4 4GA, UK; Tel:
; Fax ;
DRUG INFORMATION:
Pharmacological Action: biotechnology
Therapeutic Class Code: V7A (All Other Non-Therapeutic Products)
Clinical Indications: delivery system
Drug Status: New Drug
Molecular Code:
Extract from sample record

43. IMS R&D Focus – sample record continued…
LATEST INFORMATION:
27 September 2004: At the European Partnering & Investment Conference, 16 September 2004, London, UK, R&D focus discussed PowderMed's proprietary Powder Mediated Epidermal Delivery (PMED) technology with Clive Dix, CEO of PowderMed, and Brenda Reynolds, COO. The PMED technology has utility in the development of therapeutic DNA vaccines, and PowderMed is seeking partners interested in collaborations using the PMED technology. The technology uses the PowderJect device to propel DNA precipitated onto microscopic gold particles into the epidermis. Microscopic gold particles, 1-3 mcM in diameter, have an appropriate density and size for direct DNA delivery into immunological active antigen presenting cells (APC). Once inside the APC, the DNA elutes off the gold and produces the encoded protein; the presentation of this protein by the APC to the lymphocytes results in the generation of T-cell-mediated immune responses. The technology can be used to develop vaccines that generate T-cell mediated responses to a broad range of viral and cancer antigens….

44. Adis R&D Insight (File 107,907,ADRD)
Adis does not provide systematic, controlled indexing for easy identification of products incorporating new drug delivery technologies
However, “textword” searches using terms illustrated here will help locate pertinent records. Results could be combined with Indication keywords or Therapeutic Categories
? S DRUG()DELIVERY(3N)(SYSTEM OR TECHNOLOGY OR PLATFORM OR PROPRIETARY OR FORMULATION?)/TX
S DRUG()DELIVERY(3N)(SYSTEM OR TECHNOLOGY OR PLATFORM OR PROPRIETARY OR FORMULATION?)/TX
Extracts from sample records in handout

45. ...an injection formulation of the nonsteroidal anti-inflammatory drug meloxicam (see separate profile) using its proprietary parenteral drug delivery Biochronomer(TM) system . The formulation is in preclinical development for the treatment of inflammation following arthroscopic surgery, as...
...see separate profile: Teriparatide injection) for this indication. The technology: Macroflux(TM) is a transdermal drug delivery technology, which utilises a titanium microprojection array to create superficial pathways through the skin barrier enabling...
...is developing a proprietary formulation of anaesthetic propofol (Propofol IDD-D(TM)) using its Insoluble Drug Delivery (TM) (IDD) technology . The IDD technology is complimentary to SkyePharma's proprietary nanoparticle technology that is developed to...
Extracts from sample records – Adis R&D Insight

46. Answering medical device inquiries requires access to…
Biomedical bibliographic databases
Engineering literature
Regulatory resources
A highly focused collection of full-text industry newsletters
Subject specialty company & product directories
Market research sources (reports, statistics)
Intellectual property databases

47. Resources for Market Research include…
MARKETFULL collection of full-text syndicated market research reports
INVESTEXT (File 745,545, INVE) for access to complete investment analyst reports
Statistical sources such as…
Incidence & Prevalence (File 465, IAPV)
TableBase (File 93,BTBL)
Country profile data from ESPICOM…

48. ESPICOM Country Healthcare Reports (File 511, MDST)
Provides overviews of
Healthcare administration and provision
Manufacturing & trade regulations
Registration procedures (drug & device approval process)
Price controls
Avenues of distribution
Reports include extensive statistical data
Geographic scope: 74 nations

49. ?S CN=BRAZIL
S CN='BRAZIL'
?REPORT S1/TITLES
DIALOG(R) ONLINE TABLE OF CONTENTS
LIST OF REPORT TITLES
ITEM NUMBER, MAIN TITLE
1 Brazil 2005 Generic Markets Analysis
March /19 records
2 Brazil 2005 World Medical Market Analysis
January /49 records
3 BRAZIL 2005 World Pharmaceutical Market Analysis
January /63 records
4 Brazil 2004 World Medical Market Analysis
April /40 records
Enter one item number, P for next page, or EXIT to leave TITLES: ?2
Enter (S)ection Headings only, (C)omplete table of contents,
M to return to Main Menu Listing or EXIT to leave TITLES: ?C
Note that Generic [Drug] Market Assessments have recently been added to this database

50. Extracts from Table of Contents
MEDICAL DEVICE MARKET
2 MEDICAL DEVICE MARKET--Current Size--TABLE 1, TABLE I. SUMMARY OF THE
MEDICAL DEVICE MARKET IN BRAZIL IN Projections--TABLE 2, TABLE
II. MARKET PROJECTIONS, (US$ MILLIONS)--TABLE 3, TABLE III.
3 Outlook--TABLE 4, TABLE III. SWOT ANALYSIS OF THE BRAZILIAN MEDICAL
DEVICES MARKET--Market Structure (Part 1)--Medical Device
Imports--TABLE 5, TABLE IV. IMPORTS OF MEDICAL EQUIPMENT & SUPPLIES,
(US$000S)
4 Market Structure (Part 2)--TABLE 6, TABLE V. IMPORTS OF MEDICAL
EQUIPMENT & SUPPLIES, (% CHANGE OVER PREVIOUS YEAR)--Market
Structure (Part 3)--Domestic Production--ABIMO / SINAEMO--TABLE 7,
DOMESTIC PRODUCERS INC
Market developments--Cuts in Import Tariffs
6 KEY NATIONAL DATA PROJECTIONS--TABLE 8, TABLE VI. KEY DATA
INTERNATIONAL MARKET COMPARISONS
7 INTERNATIONAL MARKET COMPARISONS--INTERNATIONAL MARKET COMPARISONS
(Part 1)--TABLE 9, TABLE VII. THE WORLD'S TOP 50 MEDICAL DEVICE
MARKETS, (US$ MILLIONS)--TABLE 10, TABLE VIII. THE WORLD'S
TOP 50 MEDICAL DEVICE M

51. REGULATORY ENVIRONMENT
32 REGULATORY ENVIRONMENT--TABLE 41, ANVISA REGISTRATION FEES (R$);
SF=TABLE
33 Import Requirements--Purchasing Procedures
34 Technical Standards
MEDICAL DEVICE IMPORTS
40 MEDICAL DEVICE IMPORTS--MEDICAL DEVICE IMPORTS (Part 1)--TABLE 42,
IMPORTS OF MEDICAL EQUIPMENT & SUPPLIES, (US$000S)
MEDICAL DEVICE IMPORTS (Part 2)--TABLE 43, LEADING SUPPLIERS OF
MEDICAL EQUIPMENT & SUPPLIES, 2002 (US$000S)--MEDICAL DEVICE IMPORTS (Part 3)--TABLE 44, LEADING SUPPLIERS BY CATEGORY, 2002 (US$000S)
DOMESTIC PRODUCTION
42 DOMESTIC PRODUCTION--Trade Associations--ABIMO / SINAEMO--Domestic
Producers (Part 1)--Baumer--Dabi Atlante Ind. Med. Odonto. Ltda-
Dixtal Biomed Ind. Com. Ltda--EDLO
43 Domestic Producers (Part 2)--Fanem--GMReis--Gnatus--JP Ind#stria
Farmac#utica SA--Domestic Producers (Part 3)--Mediphacos
Ltda.--Multinational Activity--Scantek Medical--Siemens--St Jude
Medical
44 Exports (Part 1)--TABLE 45, EXPORTS OF MEDICAL EQUIPMENT & SUPPLIES,
(US$000S)--Exports (Part 2)--TABLE 46, LEADING
DESTINATIONS, 2002 (US$000S)
45 Exports (Part 3)--TABLE 47, BALANCE OF TRADE IN MEDICAL EQUIPMENT &
SUPPLIES, (US$000S)

52. Answering medical device inquiries requires access to…
Biomedical bibliographic databases
Engineering literature
Regulatory resources
A highly focused collection of full-text industry newsletters
Subject specialty company & product directories
Market research sources (reports, statistics)
Intellectual property databases

53. Medical Device Resources on Dialog & DataStar
See also: “Beyond Science Fiction: Medical Technology in the 21th Century” – presentation by Cindy Meisner & Beth White (Ethicon Endo-Surgery)