1. Comparing Microbes Microbes and Infectious Disease The who, what, when, and how of microbes and infectious disease.

2. Microbiology Explores microscopic organisms that include: Viruses Bacteria protozoa Parasites Fungi Algae

3. Is It Alive Microbes include a wide variety of organisms. Scientists use a set of criteria to constitute what is a living organism. – Composed of cells – Perform certain chemical process such as growth and digestion – Reproduce – Make their own nutrients or ingest nutrients from environment – Respond to a stimuli such as light and touch

4. Types of Microbes ( 3 types, these are also called Pathogens) Viruses – Have to have a host to survive/reproduce Bacteria – Do not need a host to survive/reproduce, most can survive without oxygen Parasites – Feed off of a host, usually harms the host. Does not need the host to reproduce Mosquito – Parasite (can carry malaria)

5. Viruses Microscopic organisms that get inside a healthy cell and often destroy the cell. Many viruses cause diseases such as the common cold, flu, acquired immune deficiency syndrome (AIDS). A virus CANNOT live or function on its own, it requires a host – a living thing the virus/parasite lives on or in. Antibiotics DO NOT kill viruses - Rest and fluids recommended. Vaccine or anti – viral drug is used. Avian Flu Virus

6. Viruses continued Most widespread illnesses among humans. Range from mild fevers to some forms of cancer Several other severe and fatal diseases. Transmission can be by: human contact, through water or a bite. http://phschool.com/atschool/phsciexp/active_art/virus/index.html

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8. Bacteria (Also known as a Prokaryotes) Unicellular Can live in variety of places, with oxygen, without oxygen, extreme hot or cold. Living (do not need a host to survive) Have three basic shapes

9. Bacteria (con’t) Many diseases caused by bacteria are contagious/infectious Bacterial diseases can be treated with an antibiotic. Some bacterial diseases are Strep throat, sinus infections, tuberculosis Streptococcus

10. What happens if we over use antibiotics? What is created from the overuse of antibiotics?

11. Parasites A parasite is an organism that gets its food from another living organism (a host) Lives either on or in the host. Parasites can come in the form of a protists, fungi or tiny invertebrates. Parasites cause diseases such as malaria, athlete’s foot, elephantiasis, etc. Natural selection favors adaptations that allow the parasite to efficiently exploit its host.

12. Protist & Fungi (Are Parasites) Protists such as and amoeba can cause African Sleeping Sickness Fungi – Eczema, Athlete’s Foot

13. Fungi Eukaryotic Most are multicellular heterotrophs. Adapt to its environment Attack the tissues of living plants and animals and cause disease. Major concern for humans: not only food sources becoming a competitor for nutrients from the food. Mold spores – airborne and have allergic reaction

14. Mutagens Are substances that causes a person’s cells to mutate, or change form Examples of mutagens: X-rays, cigarette smoke, even sunlight Sunlight causes skin cells to change/mutate which may cause skin cancer.

15. http://notobacco.files.wordpress.com/2009/10/mouth_cancer2.jpg Mouth Cancer caused by the use of tobacco products

16. www.drsidle.com/procedures/skin_cancer.html Skin Cancer possibly caused by exposure to sunlight

17. How Infectious Disease Spreads Vectors – transmit a pathogen from a host to a new organism. Ex: mosquito bites animal infected with malaria and then bites a person Carrier – An organism that passes diseases to others even though they may not feel sick. A human with HIV can transmit HIV virus to another human being even if they do not show any symptoms. http://www.nsf.gov/news/special_reports/ecoinf/ecoinf.htm

18. Infectious Diseases Diseases that can be passed from one living thing to another. May also be caused by animal parasites, which may be in intestines, blood or tissues. Transmitted by coughing, sneezing, direct or indirect contact. Examples: Flu, cold, measles, mumps, chicken pox, STD’s Avian Flu (H5N1) – Person contacts an infected bird. Not passed person to person. http://www.youtube.com/watch?v=iS3PO5mj-a8

19. Non-Infectious Disease Usually develop due to a mutation in the DNA or from lifestyle choices. Examples (DNA): Cancer, MS(multiple sclerosis), MD (muscular dystrophy), Cystic Fibrosis Examples of lifestyle choices: Smoking, drinking, taking drugs. These can lead to cancer, liver disease, and immune disorders.