3. 1. The important Characteristics of Carbon Forms 4 covalent bonds Forms double and triple bonds Forms long chains and rings Can bind with many other elements Even electron distribution (nonpolar molecules)

4. Isomers – molecules that have the same formula but different structures.

5. 2. Macromolecules, Monomers and Polymers (Hint: think of the meaning of the prefixes)

6. What do these words mean?

8. Polygons Polygamy Polyester

9. 2. Macromolecules, Monomers and Polymers Polymer – Smaller organic molecules join into long chains. Monomer – the individual unit that builds up polymers Macromolecules – Very large molecules

10. 3. Dehydration synthesis and Hydrolysis These two terms refer to the processes that forms monomers and polymers. Dehydration synthesis – A reaction that removes molecules of water to form polymers from monomers (http://nhscience.lonestar.edu/biol/dehydrat/dehydrat.html or http://www.youtube.com/watch?v=UyDnnD3fMaU )http://nhscience.lonestar.edu/biol/dehydrat/dehydrat.html http://www.youtube.com/watch?v=UyDnnD3fMaU Hydrolysis – The reaction that adds water to polymers to separate them to their individual monomers.

11. 4. What are the big four?

12. Three out of the 4 types of biochemical macromolecules can be found on food nutrition labels…

13. Look at the label to the left. 3 of the 4 macromolecules can be found in foods. 1____________________ 2____________________ 3____________________ (0 grams in this product) (13 grams in this product) (9 grams in this product)

15. 4. What are the big four? Fats (we call them lipids) Carbohydrates Proteins Nucleic acids (DNA and RNA)

16. When studying these biochemical molecules, we are interested in finding out….. what they do for living things. what they generally look like. what their monomers are. and how they may help the body gain energy to sustain life. SO, LETS GET STARTED!

17. 5. Carbohydrates Molecules that form from atoms in 1C:2H:1O ratio Monomers: Monosaccharides (simple sugars) Monosaccharides are usually sweet, white powdery substances (such as fructose, glucose) that form rings of carbon atoms.

18. Monosaccharides in general serve as direct, quick sources of energy for living organisms during cellular respiration, they are building blocks of many polymers Important monosaccharides: Glucose Fructose

19. Disaccharides – two monosaccharide molecules combine by dehydration synthesis to form disaccharides

20. Important disaccharides: Lactose – found in milk sugar Succrose – table sugar

21. Polysaccharides – many (tens to hundreds) units of monosaccharides combine by dehydration synthesis Polysaccharides also separate to monosaccharides by hydrolysis while taking in water.

22. Important polysaccharides: Starch – made up of many glucose units, it is an important storage polysaccharide that is found in plant roots and other tissues. It stores monosaccharides that can be broken down later to release useful energy during cellular respiration – ONLY IN PLANTS Glycogen – also made up of many glucose units, it is an important storage polysaccharide in the liver and animal muscles. It can also be broken down to monomers to release energy during cellular respiration. ONLY IN ANIMALS Cellulose – also made up of many glucose units. However, in this case the molecule is not easily broken down to its monomers. It is important for providing a rigid structure in plant cell walls.

23. Chitin – made up of some nitrogen containing monosaccharides. It is an important polysaccharide that provide the solid structure of arthropods and fungi. http://biomodel.uah.es/en/model3/index.htm

24. 6. Lipids a diverse group of molecules that are nonpolar and generally do not dissolve in water They mostly contain carbon, hydrogen, very few oxygen atoms, but some also have phosphorous. There are three distinct groups of lipids: Simple lipids Phospholipids Sterols

25. 6A. Simple Lipids Very large molecules that form from 2 different kinds of monomers by dehydration synthesis: 3 Fatty acids – are long chains of carbon with oxygen at the end (can be saturated and unsaturated) 1 Glycerol – smaller 3-carbon compound.

26. Simple lipids are important as storage materials in all living things. They can store twice as many calories as polysaccharides can. Oils (mostly from plants) contain more unsaturated fatty acids, while fats (animals) contain more saturated fatty acids. Simple lipids also dissolve vitamins http://biomodel.uah.es/en/model3/index.htm

27. 6B. Phospholipids Phospholipids – phosphate containing lipids. Their monomers: 1 glycerol + 2 fatty acids (saturated or unsaturated) + phosphate. These monomers combine by dehydration synthesis Phospholipids have both polar and nonpolar sections. As a result, they are able to dissolve in both type of solvents as well. They are important for living things because they form the borders of all cells (cell membranes) and also participate in forming many cell organelles.

29. 6C. STEROLS Sterols are a highly nonpolar (hydrophobic) group of molecules. They are formed from four rings of carbon atoms. One ring is made up of five carbons, the other three rings are made up of 6 carbons.

30. What are steroids used for? But some steroids are necessary in certain concentrations.

31. Cholesterol – important component of the cell membrane, but can be harmful if overdosed in diet. Too much cholesterol can lead to atherosclerosis and other circulatory problems. Sex hormones – responsible for normal development, sexual function, muscle and body hair formation Vitamin D – important vitamin for normal bone formation, immune functions http://biomodel.uah.es/en/model3/index.htm

32. 7.Proteins

33. Monomers: Amino acids – they are small molecules but complex themselves. Components of amino acids: Carboxyl group – COOH Amino group – NH 2 Side chain (labelled R)

34. The R group can be 20 different kinds of side chains. Because of these side chains we have 20 different types of amino acids in our body. The R group determines the characteristics of the amino acid Some amino acids are essential (our body cannot make these, so we need to take these in with our food) while others are nonessential (we can make these)

36. 7B. Combining Amino Acids Two amino acids can combine at their amino and carboxyl ends by dehydration synthesis. They form a peptide bond together. The product of this reaction is a dipeptide (2 amino acids), polypeptide (many amino acids) http://www.johnkyrk.com/aminoacid.html

37. 7C. Protein Structure Once the proper number of amino acids combine by peptide bond, we get a polypeptide chain – this is the primary structure of a protein (the number and types of amino acids combined to form a protein)

38. Secondary structure – The long polypeptide chain folds up by using H-bonds. Alpha helix – If the H-bonds form within the polypeptide chain, a spiral staircase shape is formed. Beta pleaded sheet – If the H-bonds form between longer stretches of polypeptide chains a long fan shape is formed.