2.  Other than skin cancer, breast cancer is the most common type of cancer among women in this country.  Each year, more than 211,000 American women learn they have this disease.

3.  According to the American Cancer Institute…  New cases: 182,460 (female); 1,990 (male)  Deaths: 40,480 (female); 450 (male)

4.  Cancer begins in the cells  Cells are the building blocks for tissue that makes organs  Normally, cells grow and divide to form new cells as the body needs them  Sometimes this process goes wrong and new cells form when the body does not need them and old cells do not die when they should.

5.  The extra cells can form a mass of tissue called a growth or tumor  Tumors can be either benign or malignant

6.  Cancer that forms in tissues of the breast.  Usually the ducts or the tubes that carry milk to the nipple (ductal carcinoma)  Also can form in the lobules or glands that make milk  It occurs in both men and women, although male breast cancer is rare.

9.  Not cancer: Benign tumors are rarely life- threatening.  Generally, benign tumors can be removed. They usually do not grow back.  Cells from benign tumors do not invade the tissues around them.  Cells from benign tumors do not spread to other parts of the body.

10.  Cancer: Malignant tumors are generally more serious than benign tumors. They may be life-threatening.  Malignant tumors often can be removed. But sometimes they grow back.  Cells from malignant tumors can invade and damage nearby tissues and organs.  Cells from malignant tumors can spread or metastasize to other parts of the body.

13.  Cancer cells spread by breaking away from the original or primary tumor and entering the bloodstream or lymphatic system.  The cells invade other organs and form new tumors that damage these organs  The spread of cancer is called…..  Metastasis

14.  No one knows the exact causes of breast cancer.  Doctors often cannot explain why one woman develops breast cancer and another does not.  They do know that bumping, bruising, or touching the breast does not cause cancer.  And breast cancer is not contagious. You cannot "catch" it from another person.

15.  Age… The chance of getting breast cancer goes up as a woman gets older. Most cases of breast cancer occur in women over 60. This disease is not common before menopause.  Personal History of Breast cancer  Family history (risk higher if family member got breast cancer before age 40)  Breast changes – some women have abnormal cells in the breast that increases their risk. These cells can be detected by microscope

16.  Gene changes – the BRCA1 and BRCA2 genes can be abnormal and result in increased risk  Reproductive history – the older a woman is when she has her first child, increases her chances of breast cancer  Menstrual history – women who had their first period before age 12 are at increased risk as are women who went through menopause after age 55.  Women who never had children

17.  Women who take estrogen or hormone therapy after menopause  Race : more often in white women than Latina, Asian, African American  Women who had radiation therapy to the chest before age 30  Women who are overweight after menopause may have increased risk  Women who are physically inactive may have increased risk  Studies suggest that the more alcohol a woman drinks, the greater the risk of breast cancer

18.  There is NO CURE for Breast Cancer…  Or for any cancer.  The ONLY thing that we can do is to follow recommended screening guidelines for the early detection of breast cancer.

19.  Screening helps doctors to find and treat cancer early. Treatment is more likely to work well when cancer is found early  There are three types of screening recommended:  1. Mammogram  2. Clinical Breast Exam  3. Self Breast Exam

20.  The recommendation of the American Cancer Society is:  Women at the age of 40 and older should have mammograms every 1 year.  A mammogram is a picture of the breast made with x-rays.  Women who are younger than 40 and have risk factors for breast cancer should ask their health care provider whether to have mammograms and how often to have them.

22.  Mammograms can often show a breast lump before it can be felt. They also can show a cluster of tiny specks of calcium that could be precancerous.  If an abnormal area appears on the mammogram the doctor may order an MRI to get a better view of the abnormality  Or the doctor may order a biopsy. A biopsy is the ONLY way to tell for sure if cancer is present.

24.  Mammograms are the best tool doctors have to find breast cancer early. However, mammograms are not perfect:  A mammogram may miss some cancers. (The result is called a "false negative.")  A mammogram may show things that turn out not to be cancer. (The result is called a "false positive.")  Some fast-growing tumors may grow large or spread to other parts of the body before a mammogram detects them.

25.  Clinical breast exams are recommended once a year beginning at age 18 to 20.  During a clinical breast exam, your health care provider checks your breasts. You may be asked to raise your arms over your head, let them hang by your sides, or press your hands against your hips.  Your health care provider looks for differences in size or shape between your breasts. The skin of your breasts is checked for a rash, dimpling, or other abnormal signs. Your nipples may be squeezed to check for fluid.

26.  Self Breast Exams are recommended MONTHLY beginning at age 18 to 20.  You may perform monthly breast self-exams to check for any changes in your breasts. It is important to remember that changes can occur because of aging, your menstrual cycle, pregnancy, menopause, birth control pills.  Studies have shown that self breast exams alone greatly reduce the number of deaths from breast cancer.

28.  Over prostate, cervical and breast cancer  Make sure you know all the screening methods and when to begin screening and how frequently  Know difference between benign & malignant  Risk Factors for all three  Signs and symptoms  How is cancer diagnosed?  Know about staging of cancer. We will learn today.  Gardasil  BPH

29.  Common symptoms of breast cancer include:  A change in how the breast or nipple feels › A lump or thickening in or near the breast or in the underarm area › Nipple tenderness  A change in how the breast or nipple looks › A change in the size or shape of the breast › A nipple turned inward into the breast › The skin of the breast, areola, or nipple may be scaly, red, or swollen. It may have ridges or pitting so that it looks like the skin of an orange.  Nipple discharge (fluid)

31.  Fine Needle Aspiration – the doctor uses a thin needle to remove fluid from the breast lump  Core Biopsy – the doctor uses a thick needle to remove breast tissue  Surgical Biopsy – the surgeon will remove a sample of tissue. Excisional biopsy is when the surgeon removes the entire lump or abnormal area.

32.  To plan your treatment, your doctor needs to know the extent or stage of the disease.  The stage is based on the size of the tumor and whether the cancer has spread.  Staging may involve x-rays and lab tests. These tests can show whether the cancer has spread and, if so, to what parts of your body.  When breast cancer spreads, cancer cells are often found in lymph nodes under the arm.

33.  Stage 0 is ductal or lobular carcinoma in situ  The cancer has not spread beyond the ducts or  This is EARLY breast cancer.

34.  Stage I is an early stage of invasive breast cancer.  The tumor is less than 2 centimeters (three-quarters of an inch) across. Cancer cells have not spread outside the breast. This picture shows cancer cells spreading outside the duct. The cancer cells are invading nearby tissue inside the breast.

35.  Stage II is when the tumor is 2 cm or smaller and has spread to the axillary lymph nodes or  The cancer is 2-5 cm but has not spread to the lymph nodes

36.  Stage III is locally advanced cancer. It is divided into Stage IIIA, IIIB, and IIIC.  The tumor is more than 5 cm  The tumor has spread to axillary lymph nodes

37.  Stage IV is distant metastatic cancer. The cancer has spread to other parts of the body.

38.  Surgery  Radiation  Chemotherapy  Hormone therapy  Biological therapy  Often women use more than one type of treatment

39.  Because cancer treatments often damage healthy cells and tissues, side effects are common and depend on the type and extent of treatment.

40.  Surgery is the most common treatment for breast cancer.  Breast Sparing Surgery, also called lumpectomy, segmental mastectomy or partial mastectomy

42.  Mastectomy – operation to remove the breast and often the lymph nodes under the arm

44.  The surgeon removes the whole breast and most or all of the lymph nodes under the arm.

46.  Radiation therapy uses high-energy rays to kill cancer cells. Many women receive radiation therapy after breast-sparing surgery.  The radiation destroys breast cancer cells that may remain in the area.  Some women have radiation therapy before surgery to destroy cancer cells and shrink the tumor

48.  Chemotherapy uses anticancer drugs to kill cancer cells.  Chemotherapy for breast cancer is usually a combination of drugs.  The drugs may be given as a pill or by injection into a vein – IV.  The drugs enter the bloodstream and travel throughout the body.

49.  The drugs affect cancer cells and other cells that divide rapidly:  Blood cells: These cells fight infection, help your blood to clot, and carry oxygen to all parts of the body. When drugs affect your blood cells, you are more likely to get infections, bruise or bleed easily, and feel very weak and tired.  Cells in hair roots: Chemotherapy can cause hair loss. Your hair will grow back, but it may be somewhat different in color and texture.  Cells that line the digestive tract: chemotherapy can cause poor appetite, nausea, vomiting, diarrhea and mouth and lip sores.

50.  Some breast tumors need hormones to grow. Hormone therapy keeps cancer cells from getting or using the natural hormones they need. These hormones are estrogen and progesterone.

51.  Biological therapy helps the immune system fight cancer.  The immune system is the body’s natural defense against disease.

52.  Breast Reconstruction  Some women who plan to have a mastectomy decide to have breast reconstruction. Other women prefer to wear a breast form or prothesis. Others do nothing.  There are many ways to reconstruct the breast. Some women choose to have implants made of saline or silicone.

57.  American Cancer Society  Medline Plus  www.nlm.nih.gov/.../presentations/10003 1_3.htm www.nlm.nih.gov/.../presentations/10003 1_3.htm  www.a-zbreastcancer.com/breast- cancer-picture... www.a-zbreastcancer.com/breast- cancer-picture...  http://www.ribbonofpink.com/copy/ima ges/breastAnatomy.jpg