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HIV and AIDS. Immune System Overview HIV lives in these cells.

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Presentation on theme: "HIV and AIDS. Immune System Overview HIV lives in these cells."— Presentation transcript:

1 HIV and AIDS

2 Immune System Overview HIV lives in these cells

3 Review how viruses replicate and are transmitted

4 HIV life cycle

5 Typical progress of HIV infection

6 Importance of HIV as case study 1. Diversity of viruses and viral types:

7 Importance of HIV as case study 2. Metabolism and genetics:

8 provirus stage lives inside cell, integrated with cell’s genome virion is particle that moves from cell to cell. In case of HIV, lives in blood and other body fluids: –blood: 1000-100,000 virions per ml –Semen: 10-50 virions per ml –Saliva, vaginal secretions—lower concentrations Importance of HIV as case study 3. Environment of viruses:

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10 Epidemiology of spread of AIDS Importance of HIV as case study 3. Environment of viruses: In U.S., new cases down throughout 1990’s, now on rise again—why?

11 Complicated because HIV infects cells of immune system HIV doesn’t kill, just lowers body defenses as T-cell levels drop Importance of HIV as case study 4. Immune Response:

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13 Challenges Treat patients to prevent cell-to-cell infection by virions within body Stop spread of virions from person to person (role of sex education, condoms, status of women) Develop a vaccine—why so difficult (by end of this unit understand is goal!)


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