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Alchemist TM II: Capacity, reproducibility and efficiency of an high-throughput crystallization screen preparation system. Craig Sterling Director of Business.

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Presentation on theme: "Alchemist TM II: Capacity, reproducibility and efficiency of an high-throughput crystallization screen preparation system. Craig Sterling Director of Business."— Presentation transcript:

1 Alchemist TM II: Capacity, reproducibility and efficiency of an high-throughput crystallization screen preparation system. Craig Sterling Director of Business Development Rigaku

2 CrystalTrak TM Information Flow & Management Automated Protein Crystallization Platform Alchemist TM II Screen Maker Minstrel HT & Gallery 700 Incubators Imaging and Incubation Phoenix RE Experimental Plate Setup Integration Module Including Robotic Arm, plate and block storage, mixing station, piercing station, and foil and tape sealing

3 CrystalMation TM Features  Alchemist TM II, Phoenix RE, Minstrel TM HT imaging system and Gallery TM 700 incubators operate independently or as part of the completely integrated CrystalMation system  Allows instruments to be added over time to meet budgets  Easy and seamless integration  CrystalTrak TM relational database application  Easy-to-use design is manageable by tech level personnel  Mixing, Piercing & Sealing accessories for CrystalMation TM system  Low cost operation of $10 per plate including maintenance costs and chemical costs

4 CrystalTrak TM  CrystalTrak seamlessly integrates the Rigaku Crystallization instruments, offering labs a complete end-to-end solution  Relational database tracks all of the necessary information used in crystallization trials such as chemicals, screens, protein samples, plate type information, images, and annotations  CrystalTrak simplifies and aids in the crystallization process by providing tools that enable users to greatly improve crystallization trial productivity with less user intervention.  One-click optimization tools  Intuitive screen design tools  CrystalTrak Web offers remote access to data

5 Custom Screen Maker – The Alchemist II  The best accuracy in the industry for handling stock solutions of all viscosities, dispensing volumes as low as 1µl using the Tapper TM technology  Produce liquid formulations without wasting chemicals during every cleaning, priming and wash cycle  74 Barcoded easy to swap reagents  No tedious setup, cleaning and maintenance  Dedicated syringe for each reagent  Easy screen design with CrystalTrak

6 NEW Seal-tight BirdFeeders TM  New threaded cap, Seal-tight design  Long-term storage of stock solutions on deck  Works with standard stock solution bottles  Barcode Tracking of birdfeeders and stock solutions  Autoclave-able design  Easy-pour design for replacement of stocks  Four different stock solution sizes  20ml in Birdfeeder with cap  Good for expensive stocks and additives  125ml Nalgene bottles  250ml Nalgene bottles  Three Syringe sizes (Eppendorf)  100ul  1ml  10ml

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10 Alchemist II

11 CrystalTrak TM Information Flow & Management Automated Protein Crystallization Platform Alchemist TM II Screen Maker Minstrel HT & Gallery 700 Incubators Imaging and Incubation Phoenix RE Experimental Plate Setup Integration Module Including Robotic Arm, plate and block storage, mixing station, piercing station, and foil and tape sealing


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