1. STDs Herpes genitalis & Syphilis
Dominik Kralj
Mentor: A. Žmegač Horvat

2. Herpes genitalis - ethiology
HSV-2 virus, herpesviridae family
neurotropic, neuroinvasive DNA virus

3. Primary infection acquired through sexual contact
presents itself with clusters of genital sores consisting of inflamed papules and vesicles

4. Accompanying symptoms:
pain
itching
burning
discharge
fever
headache
myalgia
lymphadenitis
malaise
dysuria
cervicitis
proctitis
reccuring infections often manifest
themselves less severely

5. Latency

6. Treatment
5 x 200mg for 5 days

7. Syphilis caused by spirochetal bacterium Treponema pallidum
known throughout history under different names (French disease, great pox, lues, Cupid’s disease)
today less prevalent but still poses a problem, especially in underdeveloped countries
has three stages

8. Primary syphilis usually through direct sexual contact
appearance of a chancre at the point of exposure after three weeks
a painless, firm skin ulceration which heals on its own after 4 to 6 weeks
sometimes accompanied by lymphadenopathy

9. Secondary syphilis
1 to 6 months after primary infection

10. Tertiary syphilis
appears following a 1atency period which lasts 1 to 10 years
characterized by formation of gummas (inflammatory granulomas)
other severe manifestations include cardiovascular syphilis, neurosyphilis, neuropathic joint disease

11. Diagnostics
Treponemal
-TPHA
-FTA-ABS
Nontreponemal
-VDRL
-RPR

12. Therapy
Penicilin G 2.4 million IU (intramuscular)

13. Thank you for your attention!