Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells 汇报人:常艳丽 专业:临床检验诊断学 导师:张青云.

Slides:



Advertisements
Similar presentations
2014 年 4 月研究生读书报告 王凯 硕士研究生 临床检验诊断学. Seminars In Cancer Biology A review of the current understanding and clinical utility of miRNAs in esophageal cancer.
Advertisements

Tumor Markers Lecture one By Dr. Reem Sallam. Objectives  To briefly introduce cancers, their incidence, some common terms, and staging system.  To.
EH 205 FALL 2009 Cancer review session Carlos O. Mendivil-Anaya, MD.
Tumor Markers Lecture one By Dr. Waheed Al-Harizi.
Figure 13.2 The Biology of Cancer (© Garland Science 2007) Hodgkins Lymphoma – A Cancer in Which 99% of the Tumor Cells Are Not Cancer Cells.
Gene therapy. Lecture Plan 1.Molecular Medicine and Gene Therapy: An Introduction 2.Vectors in Gene Therapy 1.Viral vector of gene therapy 2.Non viral.
Tumor Immunology: Definitions: -Tumor (neoplasm): unchecked cellular growth. -Two types: 1-Benign: controlled tumor. 2-Malignant: uncontrolled tumor. -Malignant.
第四篇 器械检查 第一章 心电图( Electrocardiogram ) 吕卓人 第一节 临床心电学的基本知识 第二节 心电图的测量和正常值 1 .了解心电图产生的原理 2 .熟悉常用导联、正常心电图各波的图 像、正常参考值 3 .熟悉有关心电图诊断的常用英语词汇.
Cancer Warriors Recap What does “angiogenesis” mean? New blood vessel growth How did Dr. Folkman think cancerous tumors could be stopped? Stop blood vessel.
Gene Expression Control of Gene Expression Activation of a gene that results in the formation of a _________. When transcription occurs a gene is “__________”
Control of Gene Expression
Cancer Warriors Recap What does ‘angiogenesis’ mean?
GeneGroupAnalysis BetaCS Alejandro Quiroz-Zárate John Quackenbush lab
Tumor Markers American cancer society British Journal of Cancer By B.Heidari.
Mutational analysis of 35 bladder cancer cell lines using RNA-seq.
再谈检验医学与医学检验 吕建新 温州医学院 如何定位 ?  检验医学是 “ 学科 ” 的概念  医学检验是 “ 专业 ” 的概念  国家学科专业目录(调整前)  研究生教育的学科专业目录(侧重学科)  医学(门类),共 12 个门类,  医学门类下设:基础医学、临床医学、预防医学、中医学、中.
肝胆胰腺肿瘤外科 HEPATO-PANCREATO-BILIARY SURGERY 读书汇报 科室:肝胆胰腺外二科 导师:郝纯毅教授 报告人:安启明.
Marie Curie-COFUND fellow
Cancer & Cancer clips how cancer grows and spreads how cancer grows and spreads.
Fibroblast Growth Factors (FGFs)
Cancer Cancer- a malignant tumor; the result of abnormal cell proliferation. Regulation of Cell Division –Tumor Supressor Genes Genes that inhibit cell.
Breast Cancer By Taylor Miller. Who should care? Why? Who? Every woman Why? The facts and statistics.
Bladder cancer! By Shamier Daniels. it is a disease in which abnormal cells multiply...
Fat and Breast Cancer Mei-Chun Chen, MD 1,2 ; Hsu Ma, PhD 1 Taipei Veterans General Hospital, Taiwan 1.Division of Plastic and Reconstructive Surgery,
Cancer The biological formation of cancer and treatments for the disease.
Karyotyping Cancer.
OPN -443C>T Genetic Polymorphism and Tumor OPN Expression are Associated with the Risk and Clinical Features of Papillary Thyroid Cancer in a Chinese Cohort.
Angiogenesis and hepatocellular carcinoma
Essential knowledge 3.B.2:
سرطان الثدي Breast Cancer
IL-22 Gets to the Stem of Colorectal Cancer
A B C Supplementary figure S7
Cancer makes new friends with old tricks
Unit 6 Notes: Cancer & Mutations
Mutations and Genetic Abnormalities
Serum Levels of Substance P Are Elevated in Patients With Sickle Cell Disease and Increase Further During Vaso-Occlusive Crisis by Lisa A. Michaels, Kwaku.
BIOLOGY 12 Cancer.
The BRCA1 suppressor hypothesis: An explanation for the tissue-specific tumor development in BRCA1 patients  Stephen J Elledge, Angelika Amon  Cancer.
PTEN Tumor Suppressor Extraordinaire
by Douglas D. Ross, Judith E. Karp, Tar T. Chen, and L. Austin Doyle
Hallmarks of Cancer Covered
Cancer.
Learning More from Microarrays: Insights from Modules and Networks
High-throughput analysis of informative CpG sites for the four studied tumor suppressor genes (A-D). High-throughput analysis of informative CpG sites.
Select: The Many Faces of Cancer
Angiogenesis and hepatocellular carcinoma
Serum levels of IL-21 are elevated in a subset of patients with IM
ID Proteins Regulate Diverse Aspects of Cancer Progression and Provide Novel Therapeutic Opportunities  Radhika Nair, Wee Siang Teo, Vivek Mittal, Alexander.
Table S1: Characteristics of the cancer patients
The Dual Role of Bone Morphogenetic Proteins in Cancer
Specific Tumor Suppressor Genes
Healthy volunteers (n=28) P value CRC patients         (n=30) ±9.3
Increased CCL5 expression, infiltration of Treg cells, and apoptosis of CD8+ T cells in human colorectal tissues. Increased CCL5 expression, infiltration.
CD49b+ cells from tumor-bearing mice are more prone to conversion into MDSCs compared with naive CD49b+ cells. CD49b+ cells from tumor-bearing mice are.
IL32 is highly expressed in mycosis fungoides lesional skin.
IL6 mRNA is not detected in metastatic prostate cancer cells.
Effect of naïve or SCM percentage and cytokines on expansion potential
EN1 expression in breast cancer and clinical outcome.
Mir-128 reduction in breast cancer tissues correlates chemotherapy resistance and poor patient survival. Mir-128 reduction in breast cancer tissues correlates.
Met is expressed in Her2-overexpressing cell lines and Her2 (+) breast tumors. Met is expressed in Her2-overexpressing cell lines and Her2 (+) breast tumors.
MYC–HOXB7–HER2 predicts clinical outcome in breast cancer patients treated with tamoxifen. MYC–HOXB7–HER2 predicts clinical outcome in breast cancer patients.
DAC treatment alters immune cell composition and enhances cytokine production in the peritoneal lavage. DAC treatment alters immune cell composition and.
CD24 expression. CD24 expression. A, By global gene expression, CD24 is found to be highly upregulated in SEF (80×) and in LGFMS (37×) as compared with.
Immune escape mechanisms in cancer.
Phenotypic and functional characteristics of PD-1hi B cells in HCC tissue. Phenotypic and functional characteristics of PD-1hi B cells in HCC tissue. A,
The role of RAI2 in breast cancer metastasis.
Signals and transcription factors involved in B-cell PD-1 induction.
Induction of PD-1 in B cells by TLR agonists and primary HCC-SN.
In vivo inhibition of IL-17 abrogates tumor-promoting effect of myeloid cells. In vivo inhibition of IL-17 abrogates tumor-promoting effect of myeloid.
MDSC population in patient peripheral blood.
Presentation transcript:

Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells 汇报人:常艳丽 专业:临床检验诊断学 导师:张青云

FACS analysis of CD11b+/Gr1+ cells in tumors.

Analysis of CD11b+/Gr1+ cells in healthy tissues.

Blood analyses of CD11b+/Gr1+ cells and serum analyses of cytokines.

Analysis of myeloid-derived suppressor cell levels in pericyte- rescued tumors.

FACS analysis of myeloid-derived suppressor cells from B16- IL6KD tumors and origin of IL-6 upregulation.

Biological outcomes of elevated myeloid-derived suppressor cell levels

Expression of myeloid-derived suppressor cell (MDSC)–related genes in a breast cancer patient cohort.

THANK YOU !