 What is cancer? How do cancer cells differ from other cells?  Do you know of any types of cancer? If so…name them.

signals  Cells divide only when they receive the proper signals from growth factors that circulate in the bloodstream or from a cell they directly contact.  For example, if a person loses blood, a growth factor called erythropoietin which is produced in the kidneys circulates in the bloodstream and tells the bone marrow to manufacture more blood cells.

 When a cell receives the message to divide, it goes through the cell cycle which includes several phases for the division to be completed. Checkpoints along each step of the process make sure that everything goes the way it should. cancerous.  Many processes are involved in cell reproduction and all these processes have to take place correctly for a cell to divide properly. If anything goes wrong during this complicated process, a cell may become cancerous.

 Uncontrolled Cell Growth  A disorder in which body cells lose the ability to control cell growth.

regulate uncontrollably.  Cancer cells do not respond to the signals that regulate the growth of most cells. As a result, the cells divide uncontrollably.  Cancer cells-grow  Cancer cells---Cells that grow out of control  Ignore  Ignore signals to stop dividing, to specialize, or to die and be shed  Have defects in normal cellular functions spread (mutate)  Growing in an uncontrollable manner and unable to recognize its own natural boundary, the cancer cells may spread to areas of the body where they do not belong. In a cancer cell, several genes change (mutate) and the cell becomes defective.

 Cancer cells divide uncontrollably to form a mass of cells called a tumor.

 Cancers are caused by defects in genes that regulate cell growth and division.  Some sources of gene defects are smoking tobacco, radiation exposure, defective genes, and viral infection. 

 To transmit microorganisms or cancerous cells from an original site to one or more sites elsewhere in the body

A damaged or defective p53 gene is common in cancer cells. It causes cells to lose the information needed to respond to growth signals.

 Treatment will vary depending on many different factors associated with both the type of cancer & the patient.  Some localized tumors can be removed by surgery.  Many tumors can be treated with targeted radiation.  Chemotherapy is the use of compounds that kill or slow the growth of cancer cells.

do not metastasize  Tumors that do not grow in an unlimited, aggressive manner, do not invade surrounding tissue, and does not metastasize noncancerous. does not spread  A benign tumor is noncancerous. It does not spread to surrounding healthy tissue.

 Not self-limited in its growth and is capable of invading into adjacent tissues cancerous invades destroyshealthy  A malignant tumor is cancerous. It invades and destroys surrounding healthy tissue and can spread to other parts of the body.  May be capable of spreading to distant tissues

METASTASIS  To transmit cancerous cells from an original site to one or more sites elsewhere in the body

bone cancer  Most common type of bone cancer  Affects 2x as many guys as girls  Tends to show up in people who are taller than average

 One of the most common childhood cancers  Occurs when large numbers of abnormal white blood cells called leukemic blasts fill the bone marrow & sometimes the blood stream

protect  Because these abnormal blood cells are defective, they don't help protect the body against infection the way normal white blood cells do. interfere red blood cells platelets  And because they grow uncontrollably, they take over the bone marrow and interfere with the body's production of other important types of cells in the bloodstream, like red blood cells (which carry oxygen) and platelets (which help blood to clot).

 No one knows the exact cause surgery radiation  If it is possible to remove a tumor, surgery is usually performed, followed by radiation. Some patients receive chemotherapy as well.  Survival depends on type, location & treatment

lymphatic system lymph nodes, thymus, spleen, adenoids, tonsils, bone marrow.)  Cancer that develops in the lymphatic system (the lymph nodes, thymus, spleen, adenoids, tonsils, and bone marrow.)  Most teens with lymphoma have either: Hodgkin’s disease or Non-Hodgkin’s lymphoma

 Occurs in adolescent and young  adults  Shows up in lymph nodes in neck, armpits etc.  Lymph nodes are usually enlarged but not painful

 Similar to leukemia because both might involve malignant lymphocytes (white blood cells ) and symptoms are similar

 Most common  Most common cancer in humans  Appears as a shiny translucent or pearly nodule  Most appear on skin with a history of exposure to the sun

squamous cells  Begins in the squamous cells  Tends to develop in fair-skinned middle-aged & elderly people who have had long term sun exposure

 Begins in cells within the epidermis that give skin its color lethal  Most lethal form of skin cancer

menwomen  Cancer that starts in the cells of the breast in men & women

 A disease of uncontrolled cell growth in tissues of the lung  Most common symptoms are: shortness of breath, coughing, and weight loss common men second women  the most common cause of cancer-related death in men and the second most common in women, is responsible for 1.3 million deaths worldwide annually.

male metastasize  A disease in which cancer develops in the prostate, a glad in the male reproductive system. These cells may spread (metastasize) from the prostate to other parts of the body, especially the bones and lymph nodes. men50  Most frequently in men over 50

 Many men who develop this cancer never have symptoms, undergo no therapy, and eventually die of other causes

large intestine  Cancer of the large intestine (colon), the lower part of your digestive system