Obesity and type 2 diabetes The relationship between obesity and type 2 diabetes can be clearly seen in japanese Sumo wrestlers who are massively obese.

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Presentation transcript:

Obesity and type 2 diabetes The relationship between obesity and type 2 diabetes can be clearly seen in japanese Sumo wrestlers who are massively obese and must constantly over-eat to maintain their size. The incidence of Type 2 diabetes amongst wrestlers is 60% compared with just 5% of the general population

Complications include poor circulation which may lead to persistent ulceration and eventually require limbs to be amputated

Exercise reducing diabetes? Aerobic exercise prevents type 2 diabetes by reducing body weight and body fat Note that improved insulin sensitivity is lost around 7 days after the last exercise period That is one good reason to exercise every 3 days as recommended by health officials

Effect of exercise in prevention and treatment of NIDDM Ability of cells to uptake glucose from the blood (insulin sensitivity) is greater in physically fit individuals. A decrease in insulin sensitivity with age can be prevented by regular exercise

Exercise-induced reduction in insulin resistance Due to adaptations in skeletal muscle Increased capillary network and blood flow Increase in the sensitivity of existing insulin receptors Enhanced glucose transport due to an increase in number of insulin receptors on muscle cell membrane Increased enzyme activity associated with glucose storage