A mathematical model of tumour self-seeding reveals secondary metastatic deposits as drivers of primary tumour growth by Jacob G. Scott, David Basanta,

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Presentation transcript:

A mathematical model of tumour self-seeding reveals secondary metastatic deposits as drivers of primary tumour growth by Jacob G. Scott, David Basanta, Alexander R. A. Anderson, and Philip Gerlee Interface Volume 10(82): May 6, 2013 ©2013 by The Royal Society

A schematic of a patient with a tumour in the breast showing anatomic structures as nodes in a network with physiologic vascular connections as edges. Jacob G. Scott et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

A schematic of the model of primary seeding. Jacob G. Scott et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

A schematic representation of the different possible routes of self-seeding for (a) primary seeding and (b) secondary seeding. Jacob G. Scott et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

Simulating the dynamics of primary seeding. Jacob G. Scott et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society