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Effect of oxidized low-density lipoprotein concentration polarization on human smooth muscle cells' proliferation, cycle, apoptosis and oxidized low-density.

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Presentation on theme: "Effect of oxidized low-density lipoprotein concentration polarization on human smooth muscle cells' proliferation, cycle, apoptosis and oxidized low-density."— Presentation transcript:

1 Effect of oxidized low-density lipoprotein concentration polarization on human smooth muscle cells' proliferation, cycle, apoptosis and oxidized low-density lipoprotein uptake by Zufeng Ding, Shijie Liu, Bo Yang, Yubo Fan, and Xiaoyan Deng Interface Volume 9(71):1233-1240 June 7, 2012 ©2012 by The Royal Society

2 Schematic of the experimental perfusion system. Zufeng Ding et al. J. R. Soc. Interface 2012;9:1233-1240 ©2012 by The Royal Society

3 (a) Water-filtration rate for the permeable group (diamonds) with concentration of DiI-ox-LDL varied from 10 to 200 µg ml–1. Zufeng Ding et al. J. R. Soc. Interface 2012;9:1233-1240 ©2012 by The Royal Society

4 Effect of different concentrations of ox-LDL on human SMCs proliferation assessed by MTT assay. Zufeng Ding et al. J. R. Soc. Interface 2012;9:1233-1240 ©2012 by The Royal Society

5 DiI-ox-LDL uptake by SMCs cultured on the permeable (filled bars) and non-permeable (open bars) membranes treated with varied ox-LDL suspensions for 24 h. Zufeng Ding et al. J. R. Soc. Interface 2012;9:1233-1240 ©2012 by The Royal Society

6 Effect of different concentrations of ox-LDL on SMCs' cell cycle phase analysed by flow cytometry. Zufeng Ding et al. J. R. Soc. Interface 2012;9:1233-1240 ©2012 by The Royal Society

7 Effect of different concentrations of ox-LDL on SMCs' apoptosis rate. Zufeng Ding et al. J. R. Soc. Interface 2012;9:1233-1240 ©2012 by The Royal Society


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